Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
  • Browse and search by CBS classification: Select one of the 38 CBS classification categories where you want to search by a keyword
  • Keyword register: select an initial character and browse associated keywords
  • Search by CBS edition: Select a CBS edition and find all related publications

Registered users can create a tailor made PDF of selected articles throughout CCBS search – simply use the cart icon on the right hand of each abstract to create your individual selection of abstracts. The saved items can be printed to PDF using the print function of your web browser.

      123 001
      HPTLC coupled to ESI-Tandem MS for identifying phospholipids associated to membrane proteins in photosynthetic purple bacteria
      Maria LAPIEZA, Colette JUNGAS, Maria SAVIRON, Carmen JARNE, L. MEMBRADO, J. VELA, J. ORDUNA, Rosa GARRIGA, J. GALBAN, V. CEBOLLA* (*Instituto de Carboquímica, ICB-CSIC, C/Miguel Luesma, 4, 50018 Zaragoza, Spain,

      J. Liq. Chromatogr. Relat. Technol. 42, 1-8 (2019). HPTLC of phospholipids  (phosphatidylcholines, phosphatidylethanolamines, cardiolipins and phosphatidylglycerols) associated to membrane proteins in Rhodobacter (Rb.) blasticus, Rhodospirillum (R.) rubrum and Rhodobaca (Rbc.) bogoriensis on silica gel with a 7-step gradient based on methanol - water - ethyl acetate. HPTLC was coupled to electrospray mass spectrometry (ESI-MS) using an elution head-based interface for the identification of several phospholipid species.


      Classification: 11c
      123 003
      Antibacterial potential of the phenolics extracted from the Paulownia tomentosa L. leaves as studied with use of high-performance thin-layer chromatography combined with direct bioautography
      Agnes MORICZ*, P. OTT, Magdalena KNAS, Ewa DLUGOSZ, D. KRUZSELYI, Teresa KOWALSKA, M. SAJEWICZ (*Department of Pathophysiology, Plant Protection Institute, Centre for Agricultural Research, Hungarian Academy of Sciences, Herman O. Street 15, 1022 Budapest, Hungary,

      J. Liq. Chromatogr. Relat. Technol. 42, 249-257 (2019). HPTLC of methanolic extracts from the leaves of Paulownia tomentosa on silica gel with chloroform - ethyl acetate - methanol 20:3:2. HPTLC-direct bioautography by dipping into B. subtilis cell suspension, followed by incubation at 28 °C for 2 h. Then the bioautograms were dipped into an aqueous solution of the MTT vital dye (1 mg/mL (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide), followed by incubation at 28 °C for 30 min. Further analysis by using a HPLC-DAD-MS system allowed the identification of apigenin and p-coumaric acid as highly abundant antibacterial components.

      Classification: 9, 11a
      123 005
      Thin-layer chromatography in medicinal chemistry
      Sandra SEGAN, D. OPSENICA, Dusanka OPSENICA* (*Faculty of Chemistry, University of Belgrade, Studentski trg 12-16, P.O. Box 51, 11158 Belgrade, Serbia,

      J. Liq. Chromatogr. Relat. Technol. 42, 238-248 (2019). Review of recent applications of TLC in medicinal chemistry, including the determination of lipophilicity of biologically active compounds and its influence as activity descriptors of absorption, distribution, metabolism, elimination and toxicity. Practical applications of TLC as a fast screening technique in different stages of monitoring processes were also described, including systems recently used for stability studies of selected drugs.

      Classification: 1a, 32a
      123 013
      High performance thin layer chromatography hyphenated with electrospray mass spectrometry for evaluation of nucleobases in two traditional Chinese medicinal mushrooms: A metabolomic approach
      J. MISHRA, A. BHARDWAJ, M. PAL, R. RAJPUT, K. MISRA (*Defence Institute of Physiology and Allied Sciences, Delhi 110054, India,

      J. Liq. Chromatogr. Relat. Technol. 41, 15-16 (2019). HPTLC of thymine (1), uracil (2), adenine (3), cytosine (4), guanine (5) and guanosine (6) in Ganoderma lucidum and Cordyceps sinensis on silica gel with dichloromethane - methanol - formic acid 160:45:16. Quantitative determination by absorbance measurement at 254 nm. Identification of nucleobases in the samples was reconfirmed by hyphenated HPTLC-MS. The hRF values for (1) to (6) were 83, 73, 46, 32, 23 and 10, respectively. The intermediate precision was below 5 % (n=3). 

      Classification: 21a
      123 015
      Advances in the thin layer chromatographic analysis of counterfeit pharmaceutical products: 2008–2019
      J. SHERMA, F. RABEL* (*ChromHELP, 136 Progress Ave., Woodbury, NJ 08096, USA,

      J. Liq. Chromatogr. Relat. Technol. 42, 367-379 (2019). Review of the application of TLC and HPTLC for the analysis of counterfeit pharmaceutical products published from 2008 to 2019, including methods reported in the Global Pharma Health Fund (GPHF) Minilab Manual and the U.S. Food and Drug Administration (FDA) Compendium. Applications of TLC-Raman spectrometry and TLC-mass spectrometry for the analysis of herbal medicines were also described. A special section covering the use of model process for the transfer of minilab manual and FDA compendium TLC screening methods to quantitative HPTLC-densitometry methods was also included.

      Classification: 1
      123 016
      Factor optimization study to develop and validate a reversed-phase Thin-Layer Chromatography method for the determination of trimetazidine dihydrochloride and its reported impurities in pharmaceuticals
      Suzan MAHMOUD SOLIMAN (National Organization for Drug Control and Research (NODCAR), El-Lagousa 51 Wezaret El-Ziraa St, Giza, Egypt,

      J. Planar Chromatogr. 32, 273-283 (2019). HPTLC of trimetazidine dihydrochloride (1) and its potential impurities, namely, piperazinecarboxaldehyde (2), trimethoxybenzyl alcohol (3), and trimethoxybenzaldehyde (4) on RP-18 with acetonitrile - methanol - 0.1 % aqueous ortho-phosphoric acid (pH 6.2) 9:9:2. Quantitative determination by absorbance measurement at 254 nm. The hRF values for (1) to (4) were 21, 35, 50 and 85, respectively. Linearity was between 0.05-10 µg/zone for (1), 0.05-1.1 µg/zone for (2), 0.05-1.2 µg/zone for (3) and 0.04-1.0 µg/zone for (4). The intermediate precision was below 2 % (n=9). The LOD and LOQ were 20 and 50 ng/zone for (1) to (3) and 15 and 40 ng/zone for (4), respectively. Recovery rate was 99.6 % for (1), 100.5 % for (2), 100.1 % for (3) and 99.4 % for (4).

      Classification: 32a
      123 019
      Development of an analytical method for identification of the genotoxic impurity of quetiapine fumarate by High-Performance Thin-Layer Chromatography
      P. MINIYAR*, A. THOMAS, R. KULKARNI, S. KADAM, P. CHOUHAN, S. CHITLANGE (* Sinhgad Technical Education Society’s Sinhgad Institute of Pharmacy, Narhe, Pune – 411041, India

      J. Planar Chromatogr. 32, 317-321 (2019). HPTLC of 2-chloroaniline (1) at trace levels
      in quetiapine fumarate (2) on silica gel with toluene and methanol 7:4. Quantitative determination by absorbance measurement at 235 nm. The hRF value of (1) was 85. Linearity was between 2.5-12.5 ng/zone for (1) and 400-2400 ng/zone for (2). The intermediate precision was below 2 % (n=3). The LOD and LOQ of (1) were 0.02 and 0.05 ng/zone for (1) [Editor´s note: This seems to be erroneous.] and 1.27 and 3.87 ng/zone for (2), respectively. Recovery rate ranged between 98 and 100 % for (1) and (2).

      Classification: 32a
      123 017
      A developed High-Performance Thin-Layer Chromatographic method for the determination of orlistat in pharmaceutical preparations
      S. FATHY, A. IBRAHIM, E. ELTAMANY, J. BADR* (*Department of Pharmacognosy, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt,

      J. Planar Chromatogr. 32, 329-334 (2019). HPTLC of orlistat on silica gel with chloroform - methanol 49:1. Detection by spraying with anisaldehyde - sulfuric acid, followed by heating at 120 °C for 5 min. Quantitative determination by absorbance measurement at 600 nm. The hRF value of orlistat was 75. Linearity was between 600 and 4000 ng/zone. The intermediate precision was below 2 % (n=6). The LOD and LOQ for orlistat were 140 and 466 ng/zone, respectively. Recovery rate was between 97.7 and 104.5 %.

      Classification: 32a