Fully automated sample analysis and evaluation system for routine quality control

Fully automated sample analysis and evaluation system using HPTLC plates (20 x 10 cm). The HPTLC PRO SYSTEM (patented technology) is best suited for routine quality control of analytes extracted from complex matrices, providing reproducible and reliable results.

Designed for high-throughput analysis, the HPTLC PRO SYSTEM revolutionizes the HPTLC handling process while maintaining the method’s flexibility. With individual modules for each HPTLC step, the system processes up to five HPTLC glass plates without manual intervention – thanks to time-controlled operation even overnight.

Once the HPTLC glass plates are placed in the Module PLATE STORAGE and the vials are loaded into the Module APPLICATION, the user starts the fully automated HPTLC process by a single mouse-click in the visionCATS software. The HPTLC PRO SYSTEM uses a built-in conveyor to transport plates from one module to the other, throughout the entire HPTLC process. After analysis, the plates are transported back into the Module PLATE STORAGE.

With maximized standardization and full automation, the cGMP compliant HPTLC PRO SYSTEM is capable of delivering reproducible and reliable results, while low solvent consumption keeps operating costs low.


The samples are applied as bands onto the HPTLC glass plate (20 x 10 cm) with the HPTLC PRO Module APPLICATION. Up to 75 samples can be applied autonomously. Precision of the applied volume, exact positioning and sharpness of applied zones determine the quality of the final result.


The HPTLC PRO Module DEVELOPMENT, using HPTLC glass plates (20 x 10 cm), operates completely autonomously. The activity of the stationary phase can be adjusted, and the gas phase can be actively circulated during development (conditioning, regeneration), allowing a better separation of the analytes.


Substances without chromophores or fluorophores can be visualized by automated spraying of specific reagents onto the HPTLC glass plates (20 x 10 cm) with the HPTLC PRO Module DERIVATIZATION, controlled by the HPTLC Software visionCATS. The module features an integrated plate heating unit.


Hyperspectral data, acquired with the HPTLC PRO Module DETECTION, are used to characterize and quantify all analytes. They are obtained by using polychromatic light or specific LEDs for excitation together with an imaging spectrometer. The HPTLC Software visionCATS is used for data evaluation.


HPTLC-MS coupling allows for verification of the chemical structure of analytes by Mass Spectrometry or offline collection for further analysis. Any position on the plate can be selected via the HPTLC Software visionCATS to be automatically eluted with the HPTLC PRO Module MS-INTERFACE.


Hosting two portable stackers for five clean and five processed HPTLC glass plates (20 x 10 cm) each, the HPTLC PRO Module PLATE STORAGE enables the autonomous operation of the HPTLC PRO SYSTEM by providing the system with clean plates and storing the processed plates during or after analysis.


CAMAG’s HPTLC Software visionCATS organizes the workflow of the HPTLC PRO analysis, controls the HPTLC PRO Modules, and manages all data evaluation.