Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
  • Browse and search by CBS classification: Select one of the 38 CBS classification categories where you want to search by a keyword
  • Keyword register: select an initial character and browse associated keywords
  • Search by CBS edition: Select a CBS edition and find all related publications

Registered users can create a tailor made PDF of selected articles throughout CCBS search – simply use the cart icon on the right hand of each abstract to create your individual selection of abstracts. You can export your saved items to PDF by clicking the download icon.

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      115 054
      Direct thin-layer chromatographic enantioseparation of three aromatic DL-amino acids using vancomycin as the chiral selector
      M. ZI* (Zi Min), X. LIAN (Lian Xiao), X. CHEN (Chen Xue-Xian), L. YUAN (Yuan Li-Ming) (*Department of Chemistry, Yunnan Normal University, Kumming 650 500, P.R. China, apzmdah@126.com)

      J. Planar Chromatogr. 28, 248-250 (2015). TLC of phenylalanine, tyrosine and tryptophan on silica gel prepared by adding different concentrations of vancomycin with n-butanol - methanol - water - acetic acid 25:8:6:2. The best separations of the three racemic amino acids were achieved with more than 1.86 g of vancomycin in 25 g of silica gel. Vancomycin proved to be sufficiently stable and showed good enantioselectivity.

      Classification: 18a, 38
      116 006
      Thin-layer chromatography in the analysis of biologically active ionic and ionizable compounds
      Anna PETRUCZYNIK*, L. CIESLA (*Department of Inorganic Chemistry, Medical
      University of Lublin, Lublin, Poland, anna.petruczynik@onet.pl)

      J. Planar Chromatogr. 28, 413-425 (2015). Review of the use of thin-layer chromatography for the analysis of ionizable substances. Regarding acidic and basic compounds, the review describes the use of polar adsorbents and polar bonded stationary phases as well as reversed-phase separations._x000D_

      Classification: 1b
      116 039
      Lipidomic profiling of mastoid bone and tissue from patients with chronic otomastoiditis
      F. FAZLOLLAHI*, K. KONGMANAS, N. TANPHAICHITR, J. SUH, K. FAULL, Q. GOPEN (*Department of Psychiatry and Biobehavioral Sciences, UCLA, 760 Westwood Plaza,
      CHS 68-146, Los Angeles, CA 90095, United States, farbodfazlollahi@gmail.com)

      Int. Arch. Otorhinolaryngol. 19, 141-150 (2015). HPTLC of phosphatidylcholines (1), cholesterol (2), and triacylglycerols (3) in mastoid tissue on silica gel with chloroform - methanol - water 65:25:4. Detection by spraying with orcinol (0.02 % in 50% sulfuric acid), followed by heating at 120 ºC for 3 min. To estimate the blood contamination in the extracts, the plate was further stained with Coomassie Brilliant Blue G-250 (0.03 % in 30 % methanol/100 mM NaCl) and destained with methanol (30 % in 100 mM NaCl). The contribution of blood to the lipid profiles of the tissue was insignificant. The hRF value for (1) was in the range of 0-24, and for (2) and (3) in the range of 70-100.

      Classification: 11c
      116 066
      Transfer of minilab TLC screening methods to quantitative HPTLC-densitometry for pyrazinamide, ethambutol, isoniazid, and rifampicin in a combination tablet
      J. STROCK, M. NGUYEN, J. SHERMA* (*Department of Chemistry, Lafayette College, Easton, Pennsylvania 18042, USA, shermaj@lafayette.edu)

      J. Liq. Chromatogr. Relat. Technol. 38, 1126-1130 (2015). HPTLC of pyrazinamide (1), ethambutol (2), isoniazid (3),_x000D_ and rifampicin (4) on silica gel with methanol - toluene - ammonia 24:20:1 for (2) and ethyl acetate - acetone - methanol - acetic acid 5:2:2:1 for (1), (2) and (4). Quantitative determination by absorbance measurement at 254 nm. The method is designed to apply sample and standard weights and use mobile phases and detection methods similar to the Minilab methods.

      Classification: 28a
      116 085
      (Thin-layer chromatographic fingerprint analysis of the organic acids, chromone and triterpenoid saponins in Rhizoma Cimicifugae) (Chinese)
      H. XIAO (Xiao Honghua)*, L. SUN (Sun Lei), H. JIN (Jin Hongyu), SH. MA (Ma Shuangcheng) (*Chaoyang District Inst. for Drug Contr., Beijing 100050, China)

      Chinese J. Pharm. Anal. (3), 547-553 (2014). Rhizoma Cimicifugae is a medicinal herb and one of the main ingredients of TCM preparations for the treatment of measles, sore mouth and throat, rashes, chronic diarrhea etc. For quality control, TLC of the extracts of the drug sample on silica gel with the lower phase of chloroform – methanol – water below 10 °C, detection under UV 366 nm revealed 9 pale blue zones. Detection by spraying with a freshly prepared solution of vanillin – sulfuric acid – acetic acid 1:10:1000 followed by heating at 105 ˚C until the zones are visible under UV 366 nm, this detection mode revealed 16 zones of different color. The resulting images were converted to digital profiles to carry out similarity and two-dimensional clustering analysis. The main components were identified using QTofMS with cimifugin, prim-O-glucosylcimifugin, 27-deoxyactein, and ferulic acid as references. Based on the fingerprints the genuine drugs were easily differentiated from adulterant drugs.

      Classification: 32e
      117 035
      Preparative scale MS-guided isolation of bioactive compounds using high-resolution flash chromatography
      A. AZZOLLINI, Q. FAVRE-GODAL, J. ZHANG, L. MARCOURT, S.N. EBRAHIMI, S. WANG, P. FAN, H. LOU, D. GUILLARME, E. FERREIRA QUEIROZ, J. WOLFENDER* (*Geneva-Lausanne School of Pharmacy, University of Geneva/University of Lausanne, Geneva, Switzerland; jean-luc.wolfender@unige.ch)

      Planta Medica 82, 11/12, 1051-1057 (2016). The crude ethanol extract of the aerial parts of the liverwort Chiloscyphus polyanthos, its fractions and seven pungent sesquiterpene lactones isolated therefrom were analyzed against Candida albicans strains (hypersensitive mutant DSY2621, wild-type parent CAF2-1). 20 mL of C. albicans suspension were spread and solidified on the plate charged with samples (20 µg/spot), blank (methanol) or reference (miconazole); without any development, the plate was incubated overnight at 37 °C, sprayed with methyl thiazolyl tetrazolium chloride (MTT 0.25 %) and incubated for 6 h at 37 °C to obtain a purple background. Diplophyllolide A was active on both strains, four other lactones only on DSY2621 (l-diplophyllin, dihydrodiplophyllin, ent-3-oxodiplophyllin, 3β-hydroxyeudesma-4,11-dien-12,8α-olide)._x000D_

      Classification: 4e, 29e, 32e
      117 079
      Comparison of the limits of detection and quantification of estradiol hemihydrate determined by thin-layer chromatography using different chromatographic conditions
      M. DOLOWY, A. PAJAK* (*Department of Analytical Chemistry, School of Pharmacy with the Division of Laboratory Medicine in Sosnowiec, Medical University of Silesia in Katowice, Poland, apyka@sum.edu.pl)

      J. Liq. Chromatogr. Relat. Technol. 39, 264-270 (2016). HPTLC of estradiol hemihydrate on silica gel (1) or RP-18 (2) with dichloromethane – ethyl acetate 4:1 for (1) and methanol – water 9:1 for (2). Quantitative determination by absorbance measurement at 200 nm. The LOD was 239 ng/zone using (1) and 93 ng/zone using (2).

      Classification: 13b
      117 112
      Stability-indicating chromatographic methods for the determination of sertindole
      N.A. EL-RAGEHY, N.Y. HASSAN, M. ABDELKAWY, M.A. TANTAWY* (*Anal. Chem. Dep., Fac. of Pharm., Cairo Univ., Kasr el Aini Street, 11562, Cairo, Egypt, matantawy@hotmail.com)

      J. Chromatogr. Sci. 52 (6) 559-565 (2014). TLC of sertindole subjected to stress stability studies, including acid, alkali, oxidative, photolytic and thermal degradation, on silica gel with methanol – ethyl acetate – 33 % ammonia 10:90:1, detection under UV 254 nm (the hRf was 71 for sertindole and 16 for its oxidative degradation product), identification by IR and GC/MS, quantification by densitometry at 227 nm with a linearity range of the calibration curve from 2 to 14 µg/band. The intermediate precisions and repeatabilities were < 2%. The method is suitable for quality control laboratories as stability-indicating method and for routine analysis without any preliminary separation step.

      Classification: 32c
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