Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
  • Browse and search by CBS classification: Select one of the 38 CBS classification categories where you want to search by a keyword
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      102 148
      SIMULTANEOUS ESTIMATION AND VALIDATION OF SIMVASTATIN AND EZETIMIBE BY HPTLC IN PURE AND PHARMACEUTICAl DOSAGE FORMS
      K. Shivshanker*, N. Sreekanth, N. Harikrishnan, C. Roosewelt, P. Pandiyan, G. Rao, V. Gunasekaran (*Dept. of Pharmaceutical Analysis, Vel’s College of Pharmacy, Old Pallavaram, Chennai 600117, India, kalavaivgs30@rediffmail.com)

      Asian J. Chem. 19(5), 3627-3632 (2007). TLC of simvastatin and ezetimibe on silica gel with ethyl acetate - chloroform 4:1. Quantitative determination by absorbance measurement at 220 nm. The hRf value of simvastatin was 76 and of ezetimibe 89. Linearity was between 600 and 1400 µg/mL for simvastatin and ezetimibe. The recovery (by standard addition method) was in the range of 99.7 and 99.6 % for both drugs. The proposed method is precise, accurate and can be used for routine analysis of simvastatin and ezetimibe in tablets.

      Classification: 32a
      103 044
      Capabilities and disadvantages of combined matrix-assisted laser-desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) and high-performance thin-layer chromatography (HPTLC)
      B. FUCHS, J. SCHILLER*, R. SÜSS, A. NIMPTSCH, M. SCHÜRENBERG, D. SUCKAU (*Universität Leipzig, Medizinische Fakultät, Institut für Medizinische Physik und Biophysik, Härtelstr. 16-18, 04107 Leipzig, Germany; juergen.schiller@medisin.uni-leipzig.de)

      J. Planar Chromatogr. 22, 35-42 (2009). HPTLC of phospholipids (lyso-phosphatidylcholine, sphingomyelin, phosphatidylcholin, lyso-phosphatidylethanolamine, phosphatidylinositol, phosphatidylethanolamine, phosphatidylserine, phosphatidic acid, and triacylglycerol) on silica gel with chloroform - ethanol - water - triethylamine 5:5:1:5. Detection by spraying with a solution of primulin (Direct Yellow 59). Evaluation under UV 366 nm. Detection by MALDI-TOF MS directly on the plates.

      Classification: 11c
      103 092
      Stability-indicating high-performance thin-layer chromatographic determination of levonorgestrel and ethinyloestradiol in bulk drug and in low-dosage oral contraceptives
      A.R. FAKHARI*, A.R. KHORRAMI, M. SHAMSIPUR (*Department of Chemistry, Shahid Beheshti University, Tehran, Iran)

      Anal. Chim. Acta, 572 (2), 237-242 (2006). Presentation of a stability-indicating method for simultaneous determination of the steroidal hormones levonorgestrel and ethinyloestradiol both in bulk drug and in low-dosage oral contraceptives by HPTLC on silica gel with hexane - chloroform - methanol 4:12:1. The hRf value of levonorgestrel was 65 and of ethinyloestradiol 43. The compounds were well separated from their degradation products. Quantitative determination by absorbance measurement at 225 nm. Linearity of levonorgestrel and ethinyloestradiol was 200–800 and 40–160 ng/spot, respectively.

      Classification: 32c
      103 125
      Stability indicating high-performance thin-layer chromatographic determination of gatifloxacin as bulk drug and from polymeric nanoparticles
      S.K. MOTWANI *, R.K. KHAR, F.J. AHMAD, S. CHOPRA, K. KOHLI, S. TALEGAONKAR, Z. IQBAL (*Department of Pharmaceutics, Faculty of Pharmacy, Jamia Hamdard, Hamdard Nagar, New Delhi 110062, India)

      Anal. Chim. Acta, 576 (2), 253-260 (2006). Description of a simple, sensitive, selective, precise and stability indicating method for determination of gatifloxacin both as a bulk drug and from polymeric nanoparticles by TLC on silica gel with n-propanol - methanol - 25 % ammonia 50:10:9. The hRf value of gatifloxacin was 60. Separation from degradation products (produced under acidic and basic conditions and upon wet and dry heat treatment) was good. Quantitative determination by absorbance measurement at 292 nm. Linearity was 400 - 1200 ng/spot, with a correlation coefficient of 0.9953. The limit of detection and quantitation was 3 and 8 ng/spot, respectively.

      Classification: 32c
      103 165
      (Study of the quality standard for Fangji Guanjie pills) (Chinese)
      S. ZHANG (Zhang Songan)*, Y. CAI (Cai Yaling), J. YUAN (Yuan Jinlan), X. WU (Wu Xiaohui), CH. FENG (Feng Chao), L. ZHOU (Zhou Lumin), Y. YAO (Yao Youqi), D. ZHOU (Zhou Daonian) (*Pharm. Coll., Tongji Med. Inst., MidChina Univ. Technol., Wuhan, Hubei 430030, China)

      J. Chinese Trad. Patent Med. 30 (10), 1478-1482 (2008). TLC of Fangji Guanjie pill extracts on silica gel with 1) petroleum ether (60-90 ºC) - ethyl acetate 10:1; 2) ethyl acetate - formic acid - glacial acetic acid - water 15:1:1:2; 3) petroleum ether (60-90 ºC) - ethyl acetate 17:3; 4) chloroform - methanol - water 40:10:1; 5) diethyl ether - chloroform - methanol 4:2:1. Detection 1) under UV 254 nm; 2) by spraying with 10 % sulfuric acid in ethanol; 3) by spraying with dinitrophenylhydrazine in ethanol and heating at 105 ºC; 4) by spraying with 5 % potassium iodobismuthate solution. Identification by comparison with the standards fangchinoline and tetrandrine.

      Classification: 32e
      104 035
      (Rapid identification of glucocorticoid in Chinese traditional medicinal formulations by thin-layer chromatography) (Chinese)
      R. XIA (Xia Rui)*, SH. DONG (Dong Shuying), B. CHE (Che Baoquan) (*Beijing Municip. Inst. Drug Cont., Beijing 100035, China)

      Chinese J. Pharm. Anal. 28 (3), 470-471 (2008). TLC of glucocorticoid in TCM formulations extracted with chloroform – methanol 9:1 on silica gel with dichloromethane – diethyl ether – methanol – water 385:60:15:2. Detection by spraying with a solution of tetrazolium blue chloride. Successful separation and identification of five glucocorticoids.

      Classification: 13
      104 070
      A novel and rapid HPTLC method for the analysis of rosuvastatin calcium
      V. BALI*, M. ALI, J. ALI (*Jamia Hamdard, Faculty of Pharmacy, New Delhi, India)

      60th Indian Pharmaceutical Congress PA-219 (2008). HPTLC of rosuvastatin calcium on silica gel with toluene - ethyl acetate - formic acid 9:7:1. Quantitative determination by absorbance measurement at 254 nm. The hRf value was 32. The method was linear in the range of 100-100 ng/spot, recovery was 99.7 %.

      Classification: 32a
      104 094
      A validated method for quantification of glycyrrhizin in Glycyrrhiza glabra extract by HPTLC
      A GANTAIT*, N. NEMA, A. SAHU, S. PANDIT, S. BHADRA, P. MUKHERJEE (*School of Natural Product Studies, Jadavpur University, Kolkata 700032, India)

      Abstract No. 9162, IHCB (2009). HPTLC of glycyrrhizin in methanolic (70 %) extracts of Glycyrrhiza glabra on silica gel with chloroform - methanol - water 130:72:15. Quantitative determination by absorbance measurement at 254 nm and at 420 nm after spraying with anisaldehyde reagent. The method was linear in the range of 0.8-3.8 µg/spot. The limit of detection and quantification was 0.16 and 0.52 µg/spot, respectively. Glycyrrhizin was used as bioactive marker for quality control.

      Classification: 32e
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