Chromatographia 67 (5-6), 487-490 (2008). Simultaneous determination of escitalopram oxalate and clonazepam in a combined tablet dosage form by HPTLC on silica gel aluminum plates with toluene - ethyl acetate - triethylamine 14:7:6. Quantification by densitometry at 258 nm.

Chromatographia 67 (7-8), 607-613 (2008). Quantitative estimation of the two major alkaloids strychnine and brucine in Strychnos nux vomica by TLC on silica gel with chloroform - ethyl acetate - diethyl amine 1:17:2. The hRf values for strychnine and brucine were 55 and 42 and selectivity regarding matrix was given. Recovery was between 93.1 and 99.8 % for strychnine and between 96.9 and 99.5 % for brucine. The limit of detection and quantification for strychnine was 2 and 8 ng, respectively, and for brucine 2 and 9 ng, respectively.

fruits. Indian Drugs 45(11), 908-910 (2008). HPTLC of embelin in ethanolic extract of dried fruits of Embelia ribes Burm. on silica gel with ethyl acetate - methanol 9:1. Quantitative determination by absorbance measurement at 365 nm. The total content in Embelia ribes fruit was 0.034 %. The proposed HPTLC method provides a good resolution of embelin from other constituents present in the ethanolic extract of dried fruits of Embelia ribes Burm.

60th Indian Pharmaceutical Congress PA-177, (2008). HPTLC of sibutramine hydrochloride on silica gel with benzene - methanol 9:1. Quantitative determination by absorbance measurement at 223 nm. The method was linear in the range of 2-22 µg/mL (UV-Visible) and 100-700 ng/spot (HPTLC). The recovery was 99.5-101.6 % for both methods. The proposed methods could be used for routine analysis of the drug in capsule dosage-form

Asian J. Chem. 19(2), 1487-1493 (2007). TLC of ambroxol HCl and cetirizine HCl on silica gel with methanol - ethyl acetate - toluene - ammonia 3:10:12:1. Quantitative determination by absorbance measurement at 231 nm. The hRf value of ambroxol HCl was 78 and of cetirizine HCl 40. The calibration curve response was observed between 4 and 10 µg for ambroxol HCl and 0.4 and 0.8 µg for cetirizine HCl via peak height and area. The percent drug estimated for ambroxol HCl and cetirizine HCl from marketed formulation was 99.9, 100.2 by height and 100.8, 99.1 by area respectively. Recovery of ambroxol HCl via peak height and via peak area was 102.7 and 100.0 % respectively, and for cetirizine HCl 99.3 and 98.1 %.

Indian Drugs 45 (7), 536 - 541 (2008). Chyawanprash contains many phytoconstituents, out of which gallic acid, catechin, epicatechin are considered to be responsible for the antioxidant activity and piperine is responsible for the bioavailability enhancing effect. HPTLC with toluene - ethyl acetate - formic acid - ethanol 60:40:3:4. Quantitative determination by absorbance measurement at 254 nm. The hRf values of epicatechin, catechin, gallic acid, and piperine were 13, 32, 44, and 82 respectively. Recovery was 99.0 % for epicatechin, 96.1 % for catechin, 102.5 % for gallic acid and 100.6 % for piperine in Chyawanprash. The results obtained were compared with similar formulations available in the market employing tests for identification and purity determination. The developed method may be considered as an additional tool for quality control of Chyawanprash.

Asian J. Chem. 19(4), 2955-2960 (2007). TLC of esomeprazole and domperidone on silica gel with chloroform - acetonitrile - ammonia 20:40:1. Quantitative determination by absorbance measurement at 222 nm. The hRf value was 76 for esomeprazole and 89 for domperidone. Linearity was between 600 and 1400 µg/mL for domperidone and 1200 and 2800 µg/mL for esomeprazole. Recovery (by standard addition method) was 99.6 %. The proposed method is precise, accurate and can be used for routine analysis of esomeprazole and domperidone in tablets.

J. Pharm. Res. (7)4, 229-232 (2008). HPTLC of lumefantrine and artemether on silica gel with toluene - ethyl acetate - formic acid 60:60:7. Quantitative determination by absorbance measurement of lumefantrine at 267 nm and of artemether at 561 nm. The hRf value for lumefantrine was 54 and of artemether 89. Linearity was in the range of 1200-6000 ng/spot for lumefantrine and 200-1000 ng/spot for artemether. The method was successfully applied to the analysis of commercial formulations.