Cumulative CAMAG Bibliography Service CCBS
Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.
The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:
- Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
- Browse and search by CBS classification: Select one of the 38 CBS classification categories where you want to search by a keyword
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J. Planar Chromatogr. 26, 386-394 (2013). Review of the role of TLC chambers in planar chromatography, and the merits of S-chambers in terms of reproducibility and higher peak resolution, allowing to implement 30 % faster separation and 20-30 % higher efficiency compared with unsaturated N-chamber.
J. Liq. Chromatogr. Relat. Technol. 37, 528-537 (2014). HPTLC of prednisolone acetate (1) and moxifloxacin hydrochloride (2) in pharmaceuticals on RP-18 with methanol - water 7:3 + 1 drop triethylamine. Quantitative determination by absorbance measurement at 274 nm. The hRf values for (1) and (2) were 50 and 72, respectively. Linearity was in the range of 600-3600 ng/zone for (1) and 300-1800 ng/zone for (2). LOD and LOQ were 57 and 173 ng/zone for (1) and 27 and 83 ng/zone for (2). Recoveries (by standard addition) were in the range of 100-102 % for (1) and (2). Intermediate intra- and inter-day precision was below 2 % (n=3).
J. of China Pharm. 22 (9), 14-16 (2013). Sanyu Xugu Tie plaster is a herbal TCM preparation for the treatment of traumatic injury, contusion, stasis of blood and innominate toxic swelling. For quality control, TLC on silica gel 1) for Radix Cynanchi paniculati and the standard 2'-hydroxy-4'-methoxyacetopheone, with cyclohexane – ethyl acetate 3:1, detection by spraying with 5 % ferric chloride in ethanol and heating until the zones are visible in daylight; 2) for Oleum eucalypti and the standard cineole, with cyclohexane – ethyl acetate 19:1, detection by spraying with 1 % vanillin in sulfuric acid – ethanol 1:4 and heating at 105 °C until the zones are visible in daylight; 3) for Herba sarcandrae and the standard isofraxidin, with toluene – ethyl acetate – formic acid 9:4:1, detection under UV 366 nm; 4) for Kusnezoff monkshood root and the standard acetylbenzoylaconine, with cyclohexane – ethyl acetate diethylamine 12:8:1, detection by spraying with 5 % potassium iodobismuthate in water – hydrochloric acid 200:1 and viewing in daylight.
Chinese J. of Herald of Med. 32 (2), 242-244 (2013). TLC is widely used for the analysis of active components in TCM preparations. The degree of accuracy of the detection results can be confirmed by uncertainty evaluation, by which the critical value of measurement results are judged. The uncertainty assessment for the measurement process and experimental data is part of the information which has to be submitted with drug inspection reports. In this paper the TLC determination of the oleanolic acid content of Kangbingdu Jiaonang capsules is used as an example to study the uncertainty in order to improve the accuracy and reliability of data analysis and the measuring results. TLC of the extracts and the standard oleanolic acid, on silica gel with chloroform – methanol 20:1, detection by spraying with 10 % sulfuric acid in ethanol and heating at 100 °C until the zones are visible in daylight. Quantification by densitometry at 520 nm. In summary the main factors affecting the uncertainty of the results are 1) the data calculated from the calculation curve, the uncertainty due to the least squares fitting curve, the purity of the standard sample used, weighing operation and the glassware taken; 2) the uncertainty of the sample application volume due to the application tools employed; 3) the uncertainty of the sample dilution factor due to the operation proficiency. A method for the calculation of the uncertainty corresponding to above factors in TLC determination of oleanolic acid in Kangbingdu Jiaonang capsules is presented, so that the accuracy and reliability of the results can be evaluated scientifically and an objective basis is provided to improve the executive procedure employed.
by thin-layer chromatography) (Chinese). J. of Hubei Univ. of Trad. Chinese Med. 15 (5), 38-40 (2013). Kadsura longipedunculata Finet et Gagnep. is the dried and ripe fruit of Schisandra sphenanthera Rehd. et Wils., a herbal TCM drug commonly used in TCM preparations for the treatment of cough, spermatorrhea, enuresis, diarrhea, night sweating, palpitation and insomnia. False and inferior species often appear on the market, e.g. inferior plant material was sold as high quality product after adding synthetic dyes which are harmful to human health. As this kind of adulteration is not easily identified by eye, a TLC method for rapid identification of three dyes was developed. TLC of the drug extracts and the standards carmine, erythrosine, and brilliant crocein, on silica gel with ethyl acetate – n-butanol – ethanol – ammonia – water 1:3:3:1:1, detection in daylight.
Chinese J. of Ethnomed. & Ethnopharm. 3, 41-43 (2012). Yufukang Jiaonang capsules are a herbal TCM preparation for the treatment of numbness of the tongue, language disadvantage, choke and cough when eating, aphasia, etc. For quality control, identification of the main component crude drug, the root of Salvia miltiorrhiza and the standard tanshinone llA by TLC on silica gel with toluene – ethyl acetate 19:1, detection in daylight.
HPTLC-UV densitometry
Food Addit. Contam. 31, 15-20 (2014). HPTLC of sibutramine in food supplements and soluble beverages on silica gel with toluene - methanol 9:1. Quantitative determination by absorbance measurement at 225 nm. The hRF value for sibutramine was 53. Linearity was in the range of 78-3020 ng/zone. The method was sensitive to detect 0.3 mg of sibutramine per capsule of food supplement and showed comparable results with those obtained with HPTLC-UV and HPLC-MS.
J. Planar Chromatogr. 27, 124-131 (2014). HPTLC of sparfloxacin (1) and flurbiprofen (2) on silica gel with chloroform - methanol - formic acid 7:1:1. Quantitative determination by absorbance measurement at 258 nm. The hRF values for (1) and (2) were 45 and 75. Linearity was in the range of 100-600 ng/zone for (1) and 40-800 ng/zone for (2). The intermediate/interday/intra-day precisions were below 2 % (n=6). The LOD and LOQ were 30 and 90 ng/zone for (1) and 13 and 40 ng/zone for (2), respectively. Recovery (by standard addition) was in the range of 99.3-99.9 % for (1) and 101.1-101.3 % for (2).