Research J. Pharm. and Tech. 3(3), 825-827 (2010). TLC on silica gel (plates pre-washed with methanol) with chloroform - methanol 4:1. The hRf value of aceclofenac was 38 and of diacerein 66. Densitometric evaluation at 256 nm. The linearity range was 10-50 µg/band for aceclofenac and 5-25 µg/band for diacerein. The recovery was in the range of 99.3-101.8 % for both compounds. The method was suitable for routine quality control of combined dosage forms without any interference from the excipients.

J. Chromatogr. Sci. 48(10), 825-829 (2010). TLC of ibuprofen and its impurities in pharmaceutical preparations on silica gel with toluene - ethyl acetate - glacial acetic acid 17:13:1. Quantification by densitometry. The limit of detection and quantification ranges from 0.13-0.27 µg/zone. The recovery is 96.8-99.0 % for the individual constituents. The method is suitable for routine quality-control analysis of pharmaceuticals containing ibuprofen.

Indian Drugs 47(5), 42-45 (2010). HPTLC of lamivudine and zidovudine on silica gel with acetone - toluene - methanol 2:1:2. The hRf of lamivudine was 34 and of zidovudine 74. Densitometric quantification at 267 nm for zidovudine and 272 nm for lamivudine. The method was linear in the range of 10-210 ng/band for lamivudine and 30-420 ng/band for zidovudine. The recovery was between 99.5-100.4 % for the compounds. The method is suitable for estimation of compounds in combined formulations.

International Journal of ChemTech Research 1(2), 139-141 (2009). TLC on silica gel with toluene - methanol 3:4. The hRf value was 41. Densitometric evaluation at 235 nm. The method was linear in the range of 100-500 ng/band. The average recovery was 98.9 %. The proposed method was suitable for estimation of quetiapine in bulk drug and dosage form.

Asian Journal of Chemistry 22(6), 4209-4213 (2010). HPTLC of beta-blockers on silica gel with toluene - ethyl acetate - acetone - 25 % ammonia 10:20:20:1. The method was applied to biological samples (urine and blood). The drugs were extracted from biological samples by liquid-liquid extraction. Detection at 254 nm. The corresponding separated spots were scraped from the plate, extracted with methanol and analyzed by mass spectrometry. Finally the identity was confirmed by comparing the spectra with a data library. The proposed HPTLC method coupled with MS is very sensitive and highly suitable for biological samples.

Anal. Chim. Acta 690 (2), 148-161 (2011). Chromatographic fingerprinting has been generally accepted as analytical method for the quality control of herbal medicines. This review describes the evolution of the regulations and guidelines on the quality control of herbal medicines, and reviews the established analytical techniques in TLC, HPLC, UHPLC, hydrophilic interaction chromatography, and GC. Emphasis is put on the most recent developments, such as miniaturized techniques, new stationary phases, analysis at high temperatures and multi-dimensional chromatography. The new chemometric data handling techniques are discussed.

62nd Indian Pharmaceutical Congress Abstract No. F-246 (2010). TLC of atorvastatin calcium, ezetimibe and fenofibrate on silica gel with toluene – methanol – chloroform 6:3:4. Quantitative determination by absorbance measurement at 280 nm. The method was found to be linear in the range of 100-600 ng/band for atorvastatin calcium and ezetimibe and 50-300 ng/band for fenofibrate.

62nd Indian Pharmaceutical Congress Abstract No. F-253 (2010). TLC of ambroxol hydrochloride and doxophylline on silica gel with n-butanol – toluene – ethyl acetate – 25 % ammonia 50:30:20:1. The hRf values were 36 and 45 for doxophylline and ambroxol, respectively. Quantitative determination by absorbance measurement at 258 nm. The method was linear in the range of 300-1100 ng/band for ambroxol and 100-1100 ng/band for doxophylline.