Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
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Registered users can create a tailor made PDF of selected articles throughout CCBS search – simply use the cart icon on the right hand of each abstract to create your individual selection of abstracts. The saved items can be printed to PDF using the print function of your web browser.

      124 055
      Direct bioautography hyphenated to direct analysis in real time mass spectrometry: Chromatographic separation, bioassay and mass spectra, all in the same sample run
      T.T. HÄBE, M. JAMSHIDI-AIDJI, J. MACHO, Gertrud E. MORLOCK* (*Chair of Food Science, Institute of Nutritional Science, Interdisciplinary Research Center (IFZ), Justus Liebig Univ. Giessen, Heinrich-Buff-Ring 26-32, 35392, Giessen, Germany,

      J. of Chromatogr. A 1568, 188-196 (2018). Mass spectra by DART-MS were recorded directly in situ the bioautogram, immediately after direct bioautography (DB). This allowed to detect bioactive analytes within the bioautogram and discriminate microorganism cells and polar bioassay medium ingredients which could otherwise stress the MS system. DB-DART-MS was used for bioactive compounds in cosmetics using the Bacillus subtilis and Aliivibrio fischeri bioassays for detection of Gram-positive and Gram-negative antimicrobials. Planar yeast estrogen screen was used for detection of estrogen-effective compounds. HPTLC-DART-MS of parabens in hand creams either on silica gel with petroleum ether - glacial acetic acid 20:3 or on RP-18W with methanol - water 1:1. Detection under UV 254 and 366 nm. Bioassay by immersing the neutralized chromatograms into the bacterial suspensions.

      Keywords: densitometry HPTLC
      Classification: 4e, 5b
      100 003
      High-performance thin-layer chromatography for the analysis of medicinal plants
      E. REICH*, Anne SCHIBLI (*CAMAG Laboratory, Sonnenmattstr. 11, 4132 Muttenz, Switzerland;

      Thieme Medical Publishers Inc., New York (2006). This book presents the theoretical and technical information needed to perform reliable and reproducible high-performance thin-layer chromatography (HPTLC) to establish the identity, purity, quality, and stability of raw materials, extracts, and finished botanical products. The text provides a complete overview of the techniques and common applications of HPTLC in herbal analysis. Chapters covered are theoretical concepts (stationary phase, mobile phase, TLC results, densitometry), practical aspects of modern TLC (sample preparation, selecting the stationary phase, sample application, chromatogram development, derivatization, documentation, reporting and record keeping, TLC software, standardization), typical applications in herbal analysis, method development, and validation of qualitative and quantitative HPTLC methods.

      Classification: 1a
      100 036
      Quantitative TLC Analysis of Sterol (24beta-Ethylcholesta-5,22 E,25-triene-3beta-ol) in Agnimantha (Clerodendrum phlomidis Linn)
      K. SHANKER, S.C. SINGH, S. PANT, P. SRIVASTAVA, A.K. YADAV, R. PANDEY, R.K. VERMA, M.M. GUPTA* (*Analytical Chemistry Division, Central Institute of Medicinal and Aromatic Plants, Lucknow, 226015, India)

      Chromatographia 67 (3-4), 268-274 (2008). HPTLC of 24beta-ethylcholesta-5,22E,25-triene-3beta-ol (ECTO) in the aerial part of Clerodendrum phlomidis (used as a chemical marker for the standardization of C. phlomidis plant extracts) on silica gel with chloroform - methanol 197:3. Detection by spraying with anisaldehyde reagent. Quantitative determination by densitometry in absorption mode at 650 nm. Linearity was between 150 and 400 ng/band with good correlation (r2 = 0.996).

      Classification: 13c
      100 066
      Stability Indicating HPTLC method for the Determination of Granisetron Hydrochloride in Bulk & Pharmaceutical dosage form
      J.N. ABRAHAM*, S.L.PRABHU, S.G. VASANTHARAJU, C. DINESH KUMAR, A. SHIRWAIKAR (*Manipal College of Pharmaceutical Science, Karnataka, India)

      59th Indian Pharmaceutical Congress F-95, 414, (2007). HPTLC of granisetron hydrochloride on silica gel aluminium plates with chloroform - methanol 4:1, with 0.1 mL of ammonia. The hRf value of granisetron hydrochloride was 42. Densitometry in absorbance mode at 301 nm. Linearity was between 400 and 1600 ng/zone. The limit of detection and quantification was 80 ng and 160 ng/zone, respectively. The drug was subjected to acid and alkali hydrolysis, oxidative and thermal degradation. The degration products were well separated from the main compound.

      Classification: 32a
      100 086
      HPTLC method for Simultaneous Determination of Escitalopram Oxalate & Clonazepam in Combined Tablet Dosage Form
      V.D. DHAVALE*, P.N. RANJANE, S.V. GANDHI, K.G. BOTHARA (*A.I.S.S.M.S. College of Pharmacy, Pune, Maharashtra, India)

      59th Indian Pharmaceutical Congress F-94, 413, (2007). HPTLC of escitalopram oxalate and clonazepam in combined tablet dosage form on silica gel aluminium plate with toluene - ethyl acetate - triethylamine 7:3.5%:3. Quantitative determination by densitometric scanning at 258 nm. The calibration curve was linear over a range of 250 and 2500 ng/zone for escitalopram oxalate, and 50 and 500 ng/zone for clonazepam.

      Classification: 32a
      100 104
      Separation of statin-type antihyperlipidemic drugs by reversed-phase TLC
      L. KOMSTA*, R. SKIBINSKI, A. IWANCZYK, H. HOPKALA (*Department of Medicinal Chemistry, Skubiszewski Medical University, Jaczewskiego 4, 20-090 Lublin, Poland;

      J. Planar Chromatogr. 20, 235-237 (2007). TLC of atorvastatin, cerivastatin, fluvastatin, lovastatin, and simvastatin on RP-18 in horizontal chamber with sandwich configuration with methanol - buffer eluents of different composition. The best selectivity - separation of all the compounds - was achieved with methanol - phosphate buffer pH 7.60 4:1. Detection and densitometry at 254 nm.

      Classification: 32a
      100 122
      Nyctanthes arbor-tristis as a substitute for saffron colour
      P.B. Panjabrao, N.G. Patil, O.N. Amrite, N.G. Pardesi, C.H. andGadgoli* (*Saraswathi Vidya Bhavan,s College of Pharmacy, Dombivli, India)

      Indian Drugs 44(8), 640 (2007). TLC, HPTLC and UV spectrophotometric methods have been developed and evaluated to compare the colour properties of saffron and Nyctanthes arbor-tristis which shows an orange red colour. HPTLC and TLC of methanolic extracts of saffron and calyx of Nyctanthes arbor-tristis on silica gel with ethyl acetate - isopropanol - water 13:5:2. Both extracts showed a major zone with hRf 23 corresponding to crocin, the major colour constituent of saffron. The presence of crocin was confirmed by UV spectra. TLC, HPTLC and UV data confirm the coloring similarity of Nyctanthes arbor-tristis.

      Classification: 32e
      100 140
      Estimation of Phytoflavonid Auercetin from Methanolic extract of Tylophora indica by HPTLC techinque
      V.B.A. RAJ*, S.P. DHANABAL, M.J. NANJAN, B. SURESH (*J.S.S. College of Pharmacy, Ooty, Tamil Nadu, India)

      59th Indian Pharmaceutical Congress C-176, 267, (2007). HPTLC of tylophorine, kaempferol, alpha-amyrin, and quercetin in an alcoholic extract from Tylophora indica on silica gel with ethyl acetate - formic acid - glacial acetic acid - water 100:11:11:26. Densitometry at 366 nm. The method was found suitable for the estimation of quercetin in plant drugs and their formulations.

      Classification: 32c