Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
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      132 060
      Disruption of the inositol phosphorylceramide synthase gene affects Trypanosoma cruzi differentiation and infection capacity
      N.S.A. DOS SANTOS, C.F. ESTEVEZ-CASTRO, J.P. MACEDO, D.F. CHAME, T. CASTRO-GOMES, M. SANTOS-CARDOSO, G.A. BURLE-CALDAS, C.N. COVINGTON, P.G. STEEL, T.K. SMITH, P.W. DENNY, Santuza M. R. TEIXEIRA* (*Department of Biochemistry and Immunology, Federal University of Minas Gerais, Belo Horizonte, Brazil;

      PLoS Neglected Tropical Diseases 17(09), e0011646 (2023). Samples were extracts rich in sphingolipids obtained from Trypanosoma cruzi epimastigotes, or from Leishmania major promastigotes (Trypanosomatidae), or from Chlorocebus sp. kidney Vero cells (Cercopithecidae), all cell lines incubated 2h before the extractions with ceramide N-hexanoyl-D-erythro-sphingosine coupled to fluorescent NBD-amine group (NBD = nitrobenzoxadiazolyle). Dried extracts were resuspended in chloroform – methanol (1:1) before application on TLC silica gel layers. Development with chloroform – methanol – potassium chloride 0.25 % aqueous solution 11:9:2. Visualization under automated laser scanner. Three sphingolipids were detected due to the NBD fluorescent group: sphingomyelin (hRF 42) was present in Vero cells only (negative control), whereas the targeted inositol-phosphorylceramide (IPC, hRF 70), was present in both L. major (positive control) and T. cruzi wild-type. It was absent in T. cruzi cell lines knock-out (KO) for the IPC-synthase (IPCS) gene, but present again in the add-back cell-lines (obtained with plasmide transfection of the IPCS gene into KO cells). An unknown lipid (hRF 78) was detected in all T. cruzi samples.

      Classification: 4e, 8b, 11c, 23e, 32d
      132 019
      An updated review on distribution, biosynthesis and pharmacological effects of artemisinin: A wonder drug
      N. NABI*, S. SINGH, P. SAFFEULLAH (*Department of Botany, University of Kashmir, Srinagar, Jammu and Kashmir, 190006, India,

      Phytochem. 214, 113798 (2023). Review of the distribution of artemisinin in underutilized crops of Artemisia genus, including TLC and HPTLC methods for the analysis of different plant species.

      Keywords: HPTLC review
      Classification: 8b
      132 059
      Botanical biopesticides have an influence on tomato quality through pest control and are cost-effective for farmers in developing countries
      W. AKHTER, F.M. SHAH*, MINGLU YANG**, S. FREED, M. RAZAQ*, A. GERALD MKINDI, H. AKRAM, A. ALI, K. MAHMOOD, M. HANIF (*Department of Entomology, Faculty of Agricultural Sciences and Technology, Bahauddin Zakariya University, Multan, Punjab, Pakistan; **College of Agriculture, Tarim University, Alar, Xinjiang, China; *;; **

      PLoS ONE 18(11), e0294775 (2023). Sample was an Azadirachta indica seed extract (Meliaceae). TLC on silica gel with different mobile phases: (1) diethyl ether – methanol 49:1; (2) diethyl ether – acetone 2:1; (3) isopropanol – n-hexane 11:9; (4) dichloromethane – methanol – acetic acid 95:5:1. After 30 min hot air drying,detection under UV light. The hRF values of azadirachtin A (a limonoid) were 75, 42, 44, 55, respectively. Mobile phase (1) was therefore chosen as solvent for purification of azadirachtin A and for its quantification by Fourier transform infrared spectroscopy (FTIR).

      Classification: 4e, 8b, 15a, 32e
      132 058
      In vitro antiproliferative and apoptotic effects of thiosemicarbazones based on (–)-camphene and R-(+)-limonene in human melanoma cells
      P. R. OTAVIANO SOARES, D. C. SOUZA PASSOS, F. MOREIRA da SILVA, A.P. B. da SILVA-GIARDINI, N. PEREIRA COELHO, C.M. ALVES de OLIVEIRA, L. KATO, C.C. da SILVA, Lidia GUILLO* (*Department of Biochemistry and Molecular Biology, Institute of Biological Sciences, Federal University of Goiás, Goiânia, Goiás, Brazil;

      PLoS ONE 18(11), e0295012 (2023). TLC on silica gel to monitor the synthesis of 15 new camphene-based thiosemicarbazones produced by the reaction of camphene thiosemicarbazide either with benzaldehydes, or with acetophenones, or with one of the following molecules: benzophenone, cinnamic aldehyde, ethyl pyruvate, furaldehyde, menthone, pyrrole carboxaldehyde or thiophene-carboxaldehyde. Development with n-hexane – ethyl acetate 3:7 in the case of benzaldehydes, except vanillin; or 7:3 for the vanillin derivative and all others, followed by visualization of products with resublimated iodine. The aldehyde used for compound 15 is in fact vanillin.

      Classification: 4e, 7, 8b, 15a, 17c, 23e, 24
      132 005
      Development of a high‑performance thin‑layer chromatography method for the quantification of mangiferin in different extracts of Mangifera indica L. and its antioxidant activity
      S. ADIN, I. GUPTA, M. AQIL*, M. MUJEEB, A. NAJMI (*Phytomedicine Laboratory, Department of Pharmacognosy & Phytochemistry, School of Pharmaceutical Education & Research, Jamia Hamdard, New Delhi 110062, India,

      J. Planar Chromatogr. 36, 157-167 (2023). HPTLC of mangiferin in Mangifera indica on silica gel with acetone - chloroform - formic acid - water 4:20:1:2. Quantitative determination by absorbance measurement at 350 nm. The hRF values for mangiferin was 54. Linearity was in the range of 0.2-1.0 μg/zone. Intermediate precisions were below 1 % (n=3). LOD and LOQ were 64 and 210 ng/zone, respectively. Average recovery was 100 %.

      Classification: 8b
      132 003
      Development and validation of an assay for the quantification of glycosides using high‑performance thin‑layer chromatography (HPTLC)
      S. SULTANA, K. FOSTER, M. HOSSAIN, L. LIM, C. LOCHER* (*Division of Pharmacy, School of Allied Health, University of Western Australia, Crawley 6009, Australia,

      J. Planar Chromatogr. 36, 179-190 (2023). HPTLC of genistin (1), ononin (2), rutin (3) and luteolin-6-C-glucoside (4) in rutin commercial products on silica gel with ethyl acetate - methanol - glacial acetic acid - formic acid 11:1:1:1. Detection by derivatization with natural products polyethylene glycol reagent. Quantitative determination by absorbance measurement at 254 nm. The hRF values for (1) to (4) were 50, 46, 21 and 29, respectively. Linearity was in the range of 60-300 ng/zone for (1) to (4). Intermediate precisions were below 3 % (n=3). LOD and LOQ were 8 and 24 ng/zone for (1), (2) and (4), and 11 and 32 ng/zone for (3). Recovery was between 98.2 and 102.0 % for (1), 100.5 and 100.8 % for (2), 99.8 and 101.6 % for (3) and 99.7 and 100.3 % for (4).

      Classification: 8b, 10
      131 020
      Iridoid-glycoside isolation and purification from Premna fulva leaves
      F. HE (He Feifan), X. YAN (Yan Xiaojie), N. ZHAO (Zhao Ningtao), X. JIANG (Jiang Xiaohua), Y. WEI (Wei Yulu), F. LU (Lu Fenglai), H. LI (Li Heping), D. LI (Li Dianpeng)*, Y. CHEN (Chen Yueyuan) (*Guangxi Key Laboratory of Plant Functional Phytochemicals and Sustainable Utilization, Guangxi Institute of Botany, Guangxi Zhuang Autonomous Region, P. R. China,

      J. Sep. Sci. 46, 2300059 (2023). HPTLC of iridoid and iridoid glycoside in Premna fulva on silica gel with ethyl acetate - n-butanol - water 3:1:4. Detection by spraying with 10 % sulfuric acid - ethanol chromogenic agent, followed by heating. The system showed a hRF values from 30 and 70. The method was applied for candidate solvent-system prediction with a generally useful estimate of the solvent systems (GUESS). Further analysis by high-speed counter-current chromatography.

      Classification: 8b
      131 009
      Detection of coumarin derivatives of Viola odorata cultivated in Iraq
      Zainab A. ALI*, I. SALEH, W.M.K. ALANI (*College of Pharmacy, Mustansiriah University, Baghdad, Iraq;

      J Pharm Bioallied Sci 15(Suppl.2), S948-S951 (2023). Sample was the ethyl acetate fraction of an ethanolic extract of Viola odorata aerial parts (Violaceae). Standards were coumarinic compounds: esculetin (1) and umbelliferone (2). TLC and HPTLC on silica gel with toluene – ethyl acetate – formic acid 5:4:1. Visualization under UV 254 nm and 366 nm; densitometric scanning at 366 nm. Both (1) and (2) were found in the extract (hRF values 30 and 53, respectively, in TLC). Alternative mobile phases were also tested (TLC only): toluene – ethyl acetate 1:1 (hRF values 47 and 68) and chloroform – methanol 97:3 (hRF values 20 and 41).

      Classification: 8b, 32e