Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
  • Browse and search by CBS classification: Select one of the 38 CBS classification categories where you want to search by a keyword
  • Keyword register: select an initial character and browse associated keywords
  • Search by CBS edition: Select a CBS edition and find all related publications

Registered users can create a tailor made PDF of selected articles throughout CCBS search – simply use the cart icon on the right hand of each abstract to create your individual selection of abstracts. The saved items can be printed to PDF using the print function of your web browser.

      126 020
      New hirsutinolide-type sesquiterpenoids from Vernonia cinerea inhibit nitric oxide production in LPS-stimulated RAW264.7 cells
      Li-Ming YANG KUO, Pei-Yi TSENG, Yu-Chi LIN, Chia-Ching LIAW, Li-Jie ZHANG, Keng-Chang TSAI, Zhi-Hu LIN, Hsiu-O HO*, Yao-Haur KUO (*School of Pharmacy, Taipei Medical University, Taipei, Taiwan; hsiuoho@tmu.edu.tw)

      Planta Med. 84(18), 1348-1354 (2018). A subfraction (obtained through liquid-liquid partition and column chromatography) of the ethanolic extract of whole Vernonia cinerea plants (Asteraceae, subf. Cichorioideae) was further fractioned by reverse-phase SPE (solid-phase extraction) followed by preparative TLC on silica gel layer (eluent not given). For verification, zones were detected by spraying with anisaldehyde solution with 10 % sulfuric acid, followed by heating at 100 °C. Further purification by reverse-phase HPLC allowed the isolation of 6 hirsutinolide-type sesquiterpenoids (all with a oxacyclonane forming an ether bridge), including vernolides A and B.

      Classification: 8b, 9, 15a, 32e
      126 019
      Anti-inflammatory four new 2-(2-phenylethyl)-4H-chromen-4-one derivatives from the resinous wood of Aquilaria sinensis and their inhibitory activities on neutrophil pro-inflammatory responses
      S. WANG (Wang Sin-Ling), H. LIAO (Liao Hsiang-Ruei), M. CHENG (Cheng Ming-Jen), C. SHU (Shu Chih-Wen), C. CHEN (Chen Chun-Lin), M. CHUNG (Chung Mei-Ing)*, J. CHEN (Chen Jih-Jung) (*School of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan; meinch@kmu.edu.tw)

      Planta Med. 84(18), 1340-1347 (2018). Preparative TLC on silica gel for the final purification of 15 phenylethyl-chromenone derivatives (including 3 with epoxide functions), 4 sesquiterpenoids (neopetasane, dehydrokaranone, dioxoselinene, ligudicin C) and a steroid (ergostatetraenone), all isolated through multi-step column chromatography from the ethyl-acetate fraction of a methanolic extract of Aquilaria sinensis resinous wood (Thymelaeaceae). For each compound, mobile phase, RF value and yield are given.

      Classification: 8b, 9, 15a, 32e
      126 030
      Rapid authentication of agarwood by using liquid extraction surface analysis mass spectrometry (LESA-MS)
      Y. XIE (Xie Yanqiao), L. LI (Li Linnan), Y. CHEN (Chen Yilin), Y. YANG (Yang Yangui), H. XU (Xu Hong), Z. WANG (Wang Zhengtao), L. YANG (Yang Li)* (*The MOE Key Laboratory of Standardization of Chinese Medicines and the SATCM Key Laboratory of New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine. Shanghai 201203, China, yl7@shutcm.edu.cn; xuhongtcm@shutcm.edu.cn)

      Phytochem. Anal. 31, 801-808 (2020). HPTLC of agarwood on silica gel with chloroform - methanol - distilled water 10:7:5. Detection by absorbance measurement at 254 nm. Agarotetrol was used as reference substance. Qualitative results were in agreement with the liquid extraction surface analysis mass spectrometry method.

      Classification: 8b
      126 041
      Validated simultaneous HPTLC analysis of scopoletin and gallic acid in the methanolic fraction of Jatropha glandulifera
      J. DWIVEDI, A. GUPTA, S. PALIWAL, A. RAWAT* (*Pharmacognosy and Ethnopharmacology Division, CSIRNational Botanical Research Institute, Lucknow, India, pharmacognosynbri@gmail.com)

      J. Planar Chromatogr. 33, 457-462 (2020). HPTLC of scopoletin (1) and gallic acid (2) in the aerial parts of Jatropha glandulifera on silica gel with toluene - ethyl acetate - glacial acetic acid 75:25:1. Quantitative determination by absorbance measurement at 254 nm. The hRF values for (1) and (2) were 69 and 40, respectively. Linearity was between 100 and 600 ng for (1) and (2). Intermediate precision was below 2 % (n=3). The LOD and LOQ were 70 and 200 ng for (1) and 40 and 100 ng for (2), respectively. Recovery was between 98.8 and 98.9 % for (1) and 97.4 and 98.1 % for (2).

      Classification: 7, 8b
      125 013
      Comprehensive HPTLC fingerprinting for quality control of an herbal drug – the case of Angelica gigas root
      Débora Arruda FROMMENWILER*, J. KIM, C. YOOK, T. T. T. TRAN, S. CAÑIGUERAL, E. REICH (*CAMAG Laboratory, Muttenz, Switzerland; debora.frommenwiler@camag.com)

      Planta Medica 84(6/7), 465-474 (2018). The new concept “Comprehensive HPTLC Fingerprinting” was applied to define specifications for the identification and purity assessment of Angelica gigas roots, and for the quantification of its markers: the coumarins decursin and decursinol angelate. Methanolic root extracts of A. gigas (10 reference materials, 24 commercial samples), of 26 other Apiaceae species (including 10 Angelica, 9 Ligusticum, 2 Notopterygium, 4 Peucedanum, and Levisticum officinale) and of mixtures, were developed with toluene - ethyl acetate - acetic acid 90:10:1 on HPTLC silica gel (at 33% relative humidity, chamber pre-saturated for 20 min with filter paper and developing solvent) and dried for 5 min. Detection under white and UV lights before and after derivatization by dipping into 10% sulfuric acid in methanol and then heating 3 min at 100°C. Quantitative evaluation by densitometry in fluorescence mode at UV 313 nm, and luminance was also calculated from the image pixels. The study showed the presence in A. gigas of nodakenin, decursinol, 7-demethylsuberosin, imperatorin, osthole, and isoimperatorin at hRF 0, 4, 15, 33, 38 and 44 respectively. Z-ligustilide (hRF 59) was absent from A. gigas, allowing 1) to distinguish it from several other Apiaceae species; 2) to identify in mixtures with A. gigas two common adulterants (A. acutiloba, A. sinensis) even at 1% in the root powder. Minimal content of A. gigas fingerprint markers (decursin + decursinol acetate, co-eluting at hRF 27) was assessed as 3% (w/w) based on the quantified peaks from A. gigas reference materials.

      Classification: 2f, 8b, 32e
      124 045
      Bioactivity-guided investigation of the anti-inflammatory activity of Hippophae rhamnoides fruits
      D. RÉDEI, N. KÚSZ, N. JEDLINSZKI, G. BLAZSÓ, I. ZUPKÓ, Judit HOHMANN* (*Department of Pharmacognosy, University of Szeged, Szeged, Hungary; hohmann@pharm.u-szeged.hu)

      Planta Medica 84(1), 26-33 (2018). For the monitoring of the multi-step fractionation through VLC (vacuum liquid chromatography) of the chloroform-soluble parts of a methanol – water 7:3 percolate of Hippophae rhamnoides (Eleagnaceae) fruit peels, TLC on silica gel and RP-18, detection by spraying with sulfuric acid and heating. Preparative TLC on silica gel with cyclohexane – dichloromethane – methanol 5:15:1 to isolate, from VLC subfractions, three lignans (nectandrin B, fragransin A2, saucernetindiol) that are diastereoisomers of each other.

      Classification: 7, 8b, 32e
      124 062
      Rapid isolation of a dipeptidyl peptidase IV inhibitor from Fritillaria cirrhosa by thin-layer chromatography–bioautography and mass spectrometry-directed autopurification system
      L. GU, T. TIAN, L. XIA, G. CHOU*, Z. WANG (*Key Laboratory of Standardization of Chinese Medicines, Ministry of Education, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, China, chouguixinzyb@126.com)

      J. Planar Chromatogr. 32, 447-451 (2019). HPTLC of Fritillaria cirrhosa on silica gel with ethyl acetate - methanol - ammonia solution - water 180:20:10:1. Bioautography by dipping into a 0.15 mg/mL solution of substrate Gly-Pro-p-nitroanilide hydrochloride in 50 % of ethanol, followed by ethanol removal in the hood and dipping into a 10 U/L DPP IV enzyme solution in TrisHCl buffer (pH 8.2, 70 mM), followed by incubation at 37°C for 40 min. Detection by dipping into a solution of 0.5 % sodium nitrite in 1.2 M hydrochloric acid, followed by drying slightly for 5 min and dipping into 0.05 % N-(1-naphthyl)ethylenediamine dihydrochloride solution. Further analysis by mass spectrometry using a TLC interface. The hRF value for the dipeptidyl peptidase IV inhibitor was 58.

      Classification: 4e, 8b
      124 010
      Evaluation of polyherbal ayurvedic formulation ‘Peedantak Vati’ for antiinflammatory and analgesic properties
      A. BALKRISHNA, R. RANJAN*, S.S. SAKAT, V.K. SHARMA, R. SHUKLA, K. JOSHI, R. DEVKAR, N. SHARMA, S. SAKLANI, P. PATHAK, P. KUMARI, V. AGARWAL (*Drug Discovery and Development Division, Patanjali Research Institute, Haridwar, India, ravikant.ranjan@prft.co.in)

      J. Ethnopharmacol. 235, 361-374 (2019). HPTLC of colchicine (1) and withaferin A (2) in the polyherbal ayurvedic formulation Peedantak Vati (PV) on silica gel with chloroform - 
      methanol - water - formic acid 140:13:2:4. Quantitative determination by absorbance measurement at 218 nm. The hRF values for (1) and (2) were 22 and 28, respectively. LOD and LOQ were 40 and 120 ng/zone for (1) and 120 and 240 ng/zone for (2), respectively.  

      Classification: 8b, 17c