Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
  • Browse and search by CBS classification: Select one of the 38 CBS classification categories where you want to search by a keyword
  • Keyword register: select an initial character and browse associated keywords
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Registered users can create a tailor made PDF of selected articles throughout CCBS search – simply use the cart icon on the right hand of each abstract to create your individual selection of abstracts. You can export your saved items to PDF by clicking the download icon.

      127 035
      Stability assessment of tamsulosin and tadalafil co-formulated in capsules by two validated chromatographic methods
      M. REZK, E. MOETY, M. WADIE*, M. TANTAWY (*Analytical Chemistry Department, Faculty of Pharmacy, Cairo University, KasrEl-Aini Street, ET-11562, Cairo, Egypt, mina.wa.yousif@pharma.cu.edu.eg)

      J. Sep. Sci. 44, 530-538 (2021). HPTLC of tamsulosin (1) and tadalafil (2) in presence of their degradation products (2) and (3) on silica gel with ethyl acetate - toluene - methanol - ammonia 20:10:20:3. Quantitative determination by absorbance measurement at 280 nm. The hRF values for (1) to (4) were 55, 68, 14 and 24, respectively. Linearity was between 0.5 and 25 µg/zone for (1) and (2). Intermediate precision was below 2 % (n=3). Average recovery was 99.7 % for (1) and 100.3 % for (2).

      Classification: 23e, 32a
      127 065
      Development and validation of thin‑layer chromatography and high‑performance thin‑layer chromatography methods for the simultaneous determination of linagliptin and empagliflozin in their co‑formulated dosage form
      M. RIZK, A. ATTIA, H. MOHAMED*, M. ELSHAHED (*Department of Analytical Chemistry, Faculty of Pharmacy, Helwan University, Cairo, Egypt, heba.elzayady@gmail.com)

      J. Planar Chromatogr. 33, 647-661 (2020). HPTLC of empaglifozin (1) and linagliptin (2) on silica gel with chloroform - methanol - ammonia (25 %) 100:10:1. Quantitative determination by absorbance measurement at 225 nm. The hRF values for (1) and (2) were 31 and 71, respectively. Linearity was between 100 and 5000 ng/zone for (1) and 50 and 2500 ng/zone for (2), respectively. Intermediate precision was below 2 % (n=3). The LOD and LOQ were 32 and 97 ng/zone for (1) and 14 and 42 ng/zone for (2), respectively. Average recovery was 100.1 % for (1) and 99.9 % for (2). Comparison with a similar TLC method showed no significant statistical differences.

      Classification: 9, 23e
      127 041
      Simultaneous estimation of azilsartan medoxomil and chlorthalidone by chromatography method using design of experiment and quality risk management based quality by design approach
      P. PRAJAPATI*, S. PATEL, A. MISHRA (*Department of Quality Assurance, Maliba Pharmacy College, Uka Tarsadia University, Tarsadi, Mahuva, Surat, Gujarat 394350, India, pintu.prajapati@utu.ac.in)

      J. Planar Chromatogr. 33, 631-646 (2020). HPTLC of azilsartan medoxomil (1) and chlorthalidone (2) on silica gel with toluene - methanol - ethyl acetate - formic acid 35:10:5:1. Quantitative determination by absorbance measurement at 241 nm. The hRF values for (1) and (2) were 55 and 36. Linearity was between 800 and 4000 ng/zone for (1) and 250 and 1250 ng/zone for (2), respectively. Intermediate precision was below 2 % (n=3). The LOD and LOQ were 15 and 44 ng/zone for (1) and 10 and 32 ng/zone for (2). Recovery was between 100.8 and 101.7 % for (1) and 99.4 and 101.0 % for (2).

      Classification: 23e, 32a
      126 011
      Quality risk assessment and DoE-based analytical quality by design approach to stability-indicating assay method for acidic degradation kinetic study of apremilast
      P. PRAJAPATI*, H. PATEL, S. SHAH (*Maliba Pharmacy College, Maliba Campus, Uka Tarsadia University, Bardoli, Gujarat 394350, India, pintu.prajapati@utu.ac.in)

      J. Planar Chromatogr. 33, 231-244 (2020). HPTLC of apremilast on silica gel with toluene - methanol - ethyl acetate 7:2:1. Quantitative determination by absorbance measurement at 241 nm. The hRF value for apremilast was 63. Linearity was between 200 and 1000 ng/zone. Inter-day and intra-day precision were below 1 % (n=3). The LOD and LOQ were 4 and 13 ng, respectively. Recovery rate was between 99.7 and 100.0 %. Apremilast was subjected to acidic, alkaline, oxidative, dry heat, neutral, and photolytic degradation conditions. The method was implemented using a quality risk management and quality by design approach for regulatory requirements.

      Classification: 23e
      100 049
      Comparative study of the retention of s-triazines on octadecylsilica, cyano, and amino HPTLC plates by use of a QSPR model
      Tatjana DJAKOVIC-SEKULIC*, N. PERISIC-JANJIC (*Department of Chemistry, Faculty of Sciences, University of Novi Sad, Trg D. Obradovica 3, 21000 Novi Sad, Serbia; tanja@ih.ns.ac.yu)

      J. Planar Chromatogr. 20, 365-371(2007). Estimation of retention data by use of correlation equations and physicochemical properties is a useful tool in liquid chromatography. HPTLC of an homologous series of 9 s-triazines on RP-18, cyano-, and amino phase in unsaturated chambers with aqueous solutions of the organic solvents acetonitrile, tetrahydrofuran, and dioxane. After development the dried plates were examined under UV light at 254 nm.

      Classification: 23e
      107 080
      Stability-indicating HPTLC determination of brimonidine tartrate in bulk drug and pharmaceutical dosage form
      H. BODALWALA*, P. JAIN, R. KHATAL, K. AGRAWAK (*R. C. Patel Institute of Pharmaceutical Education and Research, Karwand Naka, Shirpur, Dist. Dhule 425405 (MS), India)

      62nd Indian Pharmaceutical Congress Abstract No. F-301 (2010). TLC of brimonidine tartrate on silica gel with methanol – toluene – triethylamine 10:35:2. The hRf value was 48. Quantitative determination by absorbance measurement at 247 nm. The method was linear in the range of 100-600 ng/band. The sample was subjected to different stress conditions (acid, base, oxidative, thermal and photolytic). With the proposed method all the degradation products were well resolved from the drug.

      Classification: 23e
      107 097
      TLC densitometric fingerprint development and validation of berberine as markers in poly-herbal Unani formulations
      S. SHUKLA*, Swarnlata SARAF, S. SARAF (*University Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur, Chhattisgarh, India)

      Der Pharma Chemica 2(3), 8-18 (2010). HPTLC of berberine on silica gel with methanol – acetic acid – water 8:1:1. The band corresponding to berberine showed an hRf value of 74. Quantitative determination by absorbance measurement at 350 nm. The method was linear in the range of 100-500 ng/band. Different samples analysed by the proposed method were found to contain 11.8-12.5 mg/g berberine. The recovery was between 98.0-100.3 %.

      Classification: 23e
      116 061
      Influence of the anionic part of 1-alkyl-3-methylimidazolium-
      based ionic liquids on the chromatographic behavior of piperazine in RP-HPTLC
      D. MIESZKOWSKI, W. SROKA, M. MARSZALL* (*Department of Medicinal Chemistry, Collegium Medicum in Bydgoszcz, Jurasza 2, 85-094 Bydgoszcz, Poland, mmars@cm.umk.pl)

      J. Liq. Chromatogr. Relat. Technol. 38, 1499-1506 (2015). RP-HPTLC of piperazine in pharmaceutical formulations on RP-18 with acetonitrile - water 3:2 modified with 1.5 % tetrafluoroborate. Quantitative determination by absorbance measurement at 247 nm. The hRF value for piperazine was 43. Linearity was in the range of 0.8-2.2 μg/zone. LOD and LOQ were 0.11 and 0.34 μg/zone. The intermediate precision was below 3.5 % (n=3). Recovery was between 99 and 103 %. Significant changes and improvements regarding the hRF value were observed when tetrafluoroborate was added to the mobile phase.

      Classification: 23e