Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
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Registered users can create a tailor made PDF of selected articles throughout CCBS search – simply use the cart icon on the right hand of each abstract to create your individual selection of abstracts. The saved items can be printed to PDF using the print function of your web browser.

      106 021
      Development and validation of stability indicating HPTLC method for determination of prasugrel
      T. BOROLE*, R. MEHENDRE, M. DAMLE, K. BOTHARA (*Dept. of Pharmaceutical Chemistry, AISSMS College of Pharmacy, Pune, Maharashtra, India)

      Journal of Chemical and Pharmaceutical Research 2(4), 907-913 (2010). TLC on silica gel with dichloromethane - methanol 99:1. The hRf value of prasugrel was 58±3. Prasugrel was subjected to stress test conditions like acid, alkali, neutral hydrolysis, oxidation, dry heat, and photo degradation. The zones corresponding to degradation products were well resolved from the main drug. Densitometric evaluation in absorbance mode at 254 nm. Linearity was in the range of 300-1500 ng/band.

      Classification: 5c
      106 022
      HPTLC method development and validation quantification of paliperidone in formulations and in vitro release study
      R. PATEL*, Mrunali PATEL, K. BHATT, B. PATEL (*A. R. College of Pharmacy and G. H. Patel Institute of Pharmacy, Sardar Patel University, Vallabh Vidyanagar 388120, India,

      Analytical Methods 2, 521-531 (2010). An HPTLC method for determination for paliperidone in formulation as well as for in vitro release studies has been developed. HPTLC on silica gel with methanol - ethyl acetate 4:1. The hRf value was 54. Quantification was performed by densitometric evaluation at 254 nm. The method was linear in the range of 100-600 ng/band. The method was suitable for estimation of the drug in mucoadhesive microemulsion formulations, as well as for solubility and diffusion studies.

      Classification: 5c
      106 023
      Application of TLC-densitometry method for estimation of acebrophylline in pharmaceutical dosage forms
      W. SOLOMON*, M. MANU, R. SIVAKUMAR, P. ANAND, R. VENKATANARAYANAN (*Dept. of Pharmaceutical Analysis, RVS College of Pharmaceutical Sciences, Sulur, Coimbatore, T.N., India,

      Journal of Pharmacy Research 3(11) (2010). TLC on silica gel (plates pre-washed with methanol) with chloroform - isopropanol - toluene 8:1:1. The hRf value was 22. Densitometric evaluation at 254 nm. The method was linear in the range of 100-5000 ng/band. The recovery was in the range of 99.8-101.5 %.

      Classification: 5c
      106 129
      HPTLC determination of amoxicillin trihydrate and bromhexine hydrochloride in oral solid dosage forms
      M. DHOKA*, V. GAWANDE, P. JOSHI (*Dept. of Q.A. AISSMS College of Pharmacy, Kennedy Rd., near R.T.O. Pune 411001, M.S., India )

      J. Pharma. Sci. & Res. 2(8), 477-483 (2010). TLC on silica gel with ethyl acetate - glacial acetic acid - methanol - water 10:5:3:2. The hRf value was 51 and 74 for amoxicillin and bromhexine, respectively. Densitometric evaluation at 260 nm (bromhexine) and at 320 nm (amoxicillin). The method was linear in the range of 200-1000 ng/band and 10-30 µg/band for bromhexine and amoxicillin, respectively. The recovery was between 98.1-101.5 %.

      Classification: 5c, 28a
      107 033
      HPLC-MS or simply HPTLC for analysis of sucralose in water?
      S. GRASHORN, L. SCHUELE, Gerda MORLOCK* (*University of Hohenheim, Institute of Food Chemistry, Garbenstrasse 28, 70599 Stuttgart, Germany,

      CBS 106, 7-10 (2011). HPTLC of sucralose on silica gel (pre-washed by development with methanol, followed by drying at 100 °C for 15 min) with isopropyl acetate – methanol – water 15:3:1 up to 60 mm (migration time 15 min). Detection by dipping in aniline diphenylamine o-phosphoric acid reagent followed by heating at 120 °C for 20 min, evaluation under white light and UV 366 nm. Quantitative determination by absorbance measurement at 400 nm. Via the TLC-MS Interface the respective zones were eluted and transferred into a single-quadrupole mass spectrometer. Electrospray ionization mass spectra were recorded in full scan mode. The recovery of sucralose in drinking water was 84 ± 7 % (n=3). The limit of detection was 6 ng/band. The calibration curve (10-300 ng/band, r=0.9999, 1.3 %RSD) was suited to analyze sucralose at concentrations of 0.1-5 µg/L.

      Classification: 5c
      112 016
      Quantification of sertraline in human serum by high-performance thin-layer chromatography as a tool for pharmacotherapy adherence evaluation
      S. MENNICKENT*, R. FIERRO, M. VEGA, M. DE DIEGO, G. GODOY, C. CIFUENTES, A. MIRANDA (*Department of Pharmacy, Faculty of Pharmacy, University of Concepción, Concepción, Chile,

      J. Planar Chromatogr. 26, 358-362 (2013). HPTLC of sertraline in human serum on silica gel with toluene - ethyl acetate - methanol - glacial acetic acid 9:3:2:1. Quantitative determination by absorbance measurement at 220 nm. The hRf of sertraline was 45. Linearity was between 1 and 70 ng/zone. LOD and LOQ were 120 and 250 pg/zone. Recovery (by standard addition) was found to be 94.6-99.0 %. The % RSD values of intra- and inter-assay were between 0.9-2.8 % and 0.8-3.4 %, respectively.

      Classification: 5c
      121 023
      AMD analysis
      and determination of biocides in lens cleaning fluid
      H.CH. WEISS, F. BUDWEG, K. CZAJA, CH. ZOELL, A. KINAST* (*Currenta GmbH & Co. OHG, 41538 Dormagen Chempark, Germany,

      CBS 120, 2-4 (2018). HPTLC of 5-chloro-2-methyl-isothiazolin-3-one (CMIT) and 2-methyl-isothiazolin-3-one (MIT) on silica gel LiChrospher with a 7-step AMD gradient from 100 % methanol to 100 % dichloromethane in 6 steps, and the final step dichloromethane – n-hexane 33:67, over a total migration distance of 70 mm. Quantitative determination by absorbance measurement at 280 nm. The polynomial calibration range was between 40-200 ng/zone (sdv 2.3 %). Repeatability was <0.5 %. Biological detection with the Aliivibrio fischeri bioassay. Direct elution of target zones from the plate to the mass spectrometer. MS analysis with ESI detection in positive mode for confirmation of CMIT and MIT in lens cleaning fluid.

      Classification: 5c