Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
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      130 005
      Multiobjective optimization of microemulsion – thin layer chromatography with image processing as analytical platform for determination of drugs in plasma using desirability functions
      Noura H. ABOU-TALEB*, D. T. EL-SHERBINY, N. M. EL-ENANY, H. I. EL-SUBBAGH (*Medicinal Chemistry Department, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt; nourahemdan@yahoo.com)

      J Chromatogr A, 1619, 460945 (2020). Samples were lamotrigin as standard, or extracted with an oil-in-water microemulsion (10 µL butyl acetate, 4 mL n-butanol, 925 mg sodium dodecyl sulphate, 8.6 mL water) either from patients’ raw plasma (for separation from blood proteins) after spiking, or from commercial tablets dissolved in methanol. TLC on silica gel with a water-in-oil microemulsion of 9 mL butyl acetate, 1 mL n-butanol, 250 mg sodium dodecyl sulphate, 250 µL water. Both optimal microemulsions were predicted using Taguchi orthogonal array and Plackett-Burman design. Evaluation in UV 254 nm, quantification from the digital picture using four image processing software programs. For lamotrigin (hRF 24), limits of quantification were 170 ng for pure drug and 10 ng for spiked plasma. Linearity (in range 20–200 ng/spot) was directly obtained for the calibration curve in spiked plasma; however, for pure drug, linearity was obtained only when using log values of the calculated densities (300–3000 ng/spot).

      Classification: 3a, 3d, 5c, 23e, 32c
      129 002
      Imaging high-performance thin-layer chromatography as powerful tool to visualize metabolite profiles of eight Bacillus candidates upon cultivation and growth behavior
      S. KRUSE, F. PIERRE, Gertrud E. MORLOCK* (*Institute of Nutritional Science, and Interdisciplinary Research Centre for Biosystems, Land Use and Nutrition, Justus Liebig University Giessen, Giessen, Germany; gertrud.morlock@uni-giessen.de)

      J Chromatogr A, 1640, 461929 (2021). Study of the impact of different strains, culture media and parameters (temperature, time, rotational speed, and glucide and amino-acid supply) on the metabolite profile of bacteria. Samples were cultivation broths of Bacillus subtilis, B. licheniformis, B. pumilus and B. amyloliquefaciens, as well as their respective supernatant liquid-liquid extracts (apolar solvents only or QuEChERS method with acetonitrile and MgSO4 – NaCl mixture 4:1). HPTLC on silica gel (normal phase and RP-18), either as bands (for small volumes of extracts) or as areas for supernatants and bigger volumes of extracts. Extract areas were focused with a three-step procedure (up to 20mm with acetone, and twice with methanol); unextracted supernatants were focused twice with methanol and once with tetrahydrofuran, but the application zone of the plate had to be cut before development, due to the high matrix load. Development with ethyl acetate – methanol – water at different ratios after activation of the plate surface with magnesium chloride (33% relative humidity), evaluation in white light and UV. Detection of antibacterial compounds with Aliivibrio fischeri bioassay. Derivatization with primuline (for lipophilic substances) and diphenylamine aniline sulfuric acid reagent (for saccharides). This method allowed a fast comparison: A) of the patterns of the different strains (presence /absence and intensity of detected or antibacterial bands); B) of cultivation parameters: the number of metabolites increased with time, rotational speed (oxygen level), and at 37°C (vs. 30°C), whereas a minimal medium allowed the detection of more metabolites, due to the lower matrix load; C) of the impact of the extraction parameters: choice of the solvents (QuEChERS method had no advantage here), solvent – supernatant ratio (1:3 showed richer patterns than 1:1); D) of the HPTLC parameters used (better separation and resolution with normal phase vs. RP18 layers).

      Classification: 3a, 10a, 11c, 27
      128 054
      Fabrication of microstructured planar chromatography platforms via laser ablation
      R. MCCANN*, M. VAZQUEZ, A. STALCUP, D. BRABAZON (*I-Form Advanced Manufacturing Research Centre, Dublin City University, Dublin 9, Ireland, ronan.mccann@i-form.ie)

      J. Liq. Chromatogr. Relat. Technol. https://doi.org/10.1080/10826076.2021.1933025 (2021). Laser fabrication of open capillary microchannels on cyclic olefin polymer susbtrates as stationary phase. Microchannels of 24 µm X 68 µm depth were produced using a neodymium-doped yttrium aluminum garnetan laser (Nd:YAG). The ultra thin layer chromatography layer was used for the separation of Fast Green for food coloring (1) and rhodamine 6G (2) and compared with a comercial RP-TLC. The hRF values for (1) and (2) were 9 and 18 using the UTLC plate and 10 and 57 with the RP-TLC plate. The paper highlighted the potential to tailor the surface chemistry through known surface functionalization routes for cyclic olefin polymer susbtrates that will allow unique applications for the UTLC plate.

      Keywords: HPTLC
      Classification: 3a
      111 012
      Solid phase extraction as clean-up for pesticide residue analysis of tea samples using planar chromatographic developing techniques CBS 110, 12-15 (2013)
      W. SCHWACK, Claudia OELLIG* (*Institute of Food Chemistry, University of Hohenheim, 70599 Stuttgart, Germany, claudia.oellig@uni-hohenheim.de)

      Clean-up of matrix-rich samples using high-troughput planar solid phase extraction (HTpSPE). Black and green tea samples were spiked with 7 pesticides (acetamiprid, azoxystrobin, chlorpyrifos, fenarimol, mepanipyrim, penconazole, and primicarb) at level 0.01, 0.1 and 1 mg/kg. Extraction with acetonitrile, pre-cleaning by dispersive SPE. TLC on silica gel (prewashed with acetonitrile) of samples applied as rectangles of 3 x 16 mm first with acetonitrile - water 19:1 over 85 mm and after drying for 5 min with acetone - water 7:1 in the opposite direction over 31 mm. Detection under UV 254 and 366 nm and by dipping in primuline reagent (0.2 % in acetone - water 4:1) and detection under UV 366 nm and white light. Elution of target zones into autosampler vials by TLC-MS Interface with acetonitrile - 10 mM ammonium formate buffer 1:1, flow rate 0.2 mL/min. After clean-up the samples are free of caffeine which interferes with pesticide detection.

      Classification: 3a, 29f
      67 026
      Direct coupling of OPLC with HPLC
      E. MINCSOVICS*, M. GARAMI, E. TYIHAK, A.M. SIUOFFI, (*Factory of Laboratory Instruments Co. Ltd, Thaly K. ut 41, P.O. Box 33, H-1450 Budapest, Hungary)

      Proc. 6th Int. Symp. Instrum. Planar Chromatogr., (Interlaken 1991), Inst. Chromatogr., Bad Dürkheim, FRG, 231-234 (1991). The sample preparation system includes an OPLC chamber as an interface where samples of interest are migrated toward the column of an HPLC system. Another way of clean-up is the combination of conventional TLC with OPLC transfer. According to the chromatographic properties of unwanted sample materials, the impurities in front and/or starting zone can be eliminated while analyzable compounds from the localized area of the layer can be transferred to the HPLC system.

      Keywords:
      Classification: 3a, 4d
      116 013
      An extraction method for 17?-ethinylestradiol from water using a new kind of monolithic stir-bar
      B. SPANGENBERG*, S. FUTTERKNECHT, W. HEMMER (*University of Offenburg, Institute of Process Engineering, Badstrasse 24, 77652 Offenburg, Germany, Spangenberg@HS-Offenburg.de)

      J. Planar Chromatogr. 28, 472-475 (2015). HPTLC of 17α-ethinylestradiol (extracted from water samples using a monolithic stir-bar) on RP-18 with methanol - acetonitrile - water 2:2:1. Detection by heating at 110 °C for 10 min followed by dipping into a mixture of sulfuric acid 98 % in water 1:49 for 1 s. After dipping the plate was heated again to 110 °C for 10 min. The hRF value for 17α-ethinylestradiol was 51.

      Classification: 3a
      67 028
      Sample preparation and isolation using planar chromatographic methods
      SZ. NYIREDY, (Dep. Pharm., Swiss Fed. Inst. Technol. (ETH) Zürich, CH-8092 Zürich, Switzerland)

      Anal. Chim. Acta 236, 83-97 (1990). Summary of the state of art of various preparative planar liquid chromatographic methods for off-line and on-line sample application. Discussion of sample purification possibilities for PLC techniques. Suggestions in form of flow charts for purification and isolation strategies using forced-flow planar chromatographic techniques, such as OPLC, etc.

      Keywords: review
      Classification: 3a
      117 030
      A critical analysis of publication trends from 2005–2015 in microwave assisted extraction of botanicals – How far we have come and the road ahead
      V. MANDAL*, R. TANDEY (*Institute of Pharmacy, Guru Ghasidas Central University, Bilaspur 495009, India, pharmafriend@rediffmail.com)

      Trends Anal. Chem. 82, 100-108 (2016). Review on the application of microwave assisted extraction of bioactives from plant matrix. The review discussed microwave assisted extraction coupled with HPTLC as a technique for the analysis of individual phenolic antioxidants.

      Keywords: HPTLC review
      Classification: 3a