Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
  • Browse and search by CBS classification: Select one of the 38 CBS classification categories where you want to search by a keyword
  • Keyword register: select an initial character and browse associated keywords
  • Search by CBS edition: Select a CBS edition and find all related publications

Registered users can create a tailor made PDF of selected articles throughout CCBS search – simply use the cart icon on the right hand of each abstract to create your individual selection of abstracts. You can export your saved items to PDF by clicking the download icon.

      130 005
      Multiobjective optimization of microemulsion – thin layer chromatography with image processing as analytical platform for determination of drugs in plasma using desirability functions
      Noura H. ABOU-TALEB*, D. T. EL-SHERBINY, N. M. EL-ENANY, H. I. EL-SUBBAGH (*Medicinal Chemistry Department, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt;

      J Chromatogr A, 1619, 460945 (2020). Samples were lamotrigin as standard, or extracted with an oil-in-water microemulsion (10 µL butyl acetate, 4 mL n-butanol, 925 mg sodium dodecyl sulphate, 8.6 mL water) either from patients’ raw plasma (for separation from blood proteins) after spiking, or from commercial tablets dissolved in methanol. TLC on silica gel with a water-in-oil microemulsion of 9 mL butyl acetate, 1 mL n-butanol, 250 mg sodium dodecyl sulphate, 250 µL water. Both optimal microemulsions were predicted using Taguchi orthogonal array and Plackett-Burman design. Evaluation in UV 254 nm, quantification from the digital picture using four image processing software programs. For lamotrigin (hRF 24), limits of quantification were 170 ng for pure drug and 10 ng for spiked plasma. Linearity (in range 20–200 ng/spot) was directly obtained for the calibration curve in spiked plasma; however, for pure drug, linearity was obtained only when using log values of the calculated densities (300–3000 ng/spot).

      Classification: 3a, 3d, 5c, 23e, 32c
      127 036
      Influence of cation transporters (OCTs and MATEs) on the renal and hepatobiliary disposition of [11C]metoclopramide in mice
      I. HERNANDEZ, S. MAIRINGER, M. SAUBERER, J. STANEK, T. FILIP, T, WANEK, G. CIARIMBOLI, N. TOURNIER, O. LANGER* (*Department of Clinical Pharmacology, Medical University of Vienna, 1090 Vienna, Austria,

      Pharm. Res. 38, 127-140 (2021). HPTLC of [11C]metoclopramide in plasma, kidney, urine and liver extracts on silica gel with ethyl acetate - ethanol - 25 % ammonium hydroxide 16:4:1. Detection using a multisensitive phosphor screen. The hRF value for [11C]metoclopramide was 60. The method allowed kinetic analysis in different organs after radiotracer injection in mice.


      Classification: 32c, 34
      125 003
      A simple, rapid and sensitive high-performance thin-layer chromatographic method for the simultaneous estimation of berberine and 5-fluorouracil in rabbit plasma
      P. TAMANE*, R. PAI, V. POKHARKAR (*Department of Drug Regulatory Affairs, Bharati Vidyapeeth (Deemed to be) University, Poona College of Pharmacy, Erandwane, Pune, Maharashtra 411038, India,

      J. Planar Chromatogr. 33, 169-177 (2020). HPTLC of berberine (1) and 5-fluorouracil (2) in rabbit plasma on silica gel with toluene - methanol - ethyl acetate - formic acid 6:2:6:1. Quantitative determination by absorbance measurement at 266 nm. The hRF values for (1) and (2) were 28 and 57, respectively. Linearity was between 20 and 300 ng/zone for both (1) and (2). Intermediate precisions were below 7 % (n=3). The LOQ was 29 ng/zone for (1) and 26 ng/zone for (2), respectively. Average recovery was 86.5 % for (1) and 87.2 % for (2).

      Classification: 32c
      124 052
      Simultaneous determination of thalidomide and dexamethasone in rat plasma by validated HPLC and HPTLC with pharmacokinetic study
      N.S. ABDELWAHAB, N.W. ALI, M.M. ZAKI*, S.M.Z. SHARKAWI, M.M. ABDELKAWY (*Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Beni-Suef University, Alshaheed Shehata Ahmed Hegazy St., Beni-Suef, Egypt,

      J. of Chromatogr. Sci. 57 (2), 130-138 (2019). Development of a method for the simultaneous determination of thalidomide (THD) and dexamethasone (DEX) in rat plasma using paracetamol as an internal standard by HPTLC on silica gel with methylene chloride - acetone - ethyl acetate 7:4:1. Detection by absorption measurement at 235 nm. Linearity was in the range of 0.02 - 100 µg/zone for THD and 0.02 - 3 µg/zone for DEX. LOD and LOQ were 7 and 20 ng/zone both for THD and DEX. Validation by testing all parameters using quality control samples as per FDA guidelines. Successful application of the method to study the pharmacokinetic parameters of both THD and DEX after their intra-peritoneal administration.

      Classification: 32c
      124 030
      Herb–drug interaction of quercetin on the pharmacokinetics of losartan in rats: a high-performance thin-layer chromatography study
      S. JADHAO, A. THOMAS*, A. RAJE, S. NAGRIK, L. KOTHAPALLI, A. SHAIKH (*Department of Pharmaceutical Quality Assurance, Dr. D.Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune, India,

      J. Planar Chromatogr. 32, 401-409 (2019). HPTLC of losartan potassium in plasma on silica gel with toluene - ethyl acetate - acetone - formic acid 8:8:2:1. Quantitative determination by absorbance measurement at 240 nm. The hRF value for losartan was 57. Linearity was between 50 and 1200 ng/mL. Intermediate precision was below 3 % (n=6). Recovery rate was between 95 and 99 %.

      Classification: 32c
      100 067
      Separation of plant Constituents form Caesalpinia Bonduc (L
      P.B. ASWAR*, P.S. GANGANE, R.D. JAWARKAR (*I.B.S.S.B’S. College of Pharmacy, Malkapur, Buidhana, Maharashtri, India)

      59th Indian Pharmaceutical Congress C-100, 248, (2007). An HPTLC method has been developed for the estimation of flavonoids tannin and saponin in Caesalpinia bonduc. The dried powdered leaves of the plant were extracted with methanol and used for evaluation. HPTLC on silica gel with ethyl acetate - formic acid - glacial acetic acid - water 20:2:2:5 for flavonoids, chloroform - glacial acetic acid - methanol - water 16:8:3:2 for saponin, and ethyl acetate - toluene - formic acid 6:6:1 for tannin. Detection by spraying with 5 % methanolic sulphuric acid for saponin, 5 % alcoholic aluminium chloride solution for flavonoids, and 5 % ferric chloride solution for tannin. Densitometric evaluation at 254 nm and 366 nm.

      Classification: 32c
      100 174
      Determination of Rutin in Amaranthus spinosus Linn
      V.L. SURYAVANSHI*, P.A. SATHE, M.M. BAING, G.R. SINGH, S.N. LAKSHMI (*Department of Chemistry, S.P. Mandali’s Ramnarain Ruia College, Matunga, Mumbai, 400 019, India;

      Whole Plant Powder by HPTLC. Chromatographia 65 (11-12), 767-769 (2007). HPTLC of rutin in the whole plant powder of Amaranthus spinosus Linn. on silica gel with ethyl acetate - formic acid - methanol - distilled water 100:9:11:17. Quantification by densitometry at 363 nm. Linearity was between 10 and 60 µg/mL for rutin. The concentration of rutin in the whole plant powder was found to be 0.15 %.

      Classification: 32c
      103 090
      Stability-indicating HPTLC method for quantitation of quetiapine fumarate in the pharmaceutical dosage form
      S.R. DHANESHWAR*, N.G. PATRE*, M.V. MAHADIK (*Bharati Vidyapeeth University, Poona College of Pharmacy, Department of Pharmaceutical Chemistry, Pune 411038, India)

      Acta Chromatographica 21 (1), 83-93 (2009). HPTLC of quetiapine fumarate on silica gel with toluene - methanol 4:1. The hRf value of quetiapine fumarate was 37. Quantitative determination by absorbance measurement at 254 nm. There was no chromatographic interference from tablet excipients. The drug is susceptible to treatment with acid and alkaline hydrolysis, oxidation, and photodegradation. The method was able to separate the degradation products from the pure drug, it can be used for stability tests.

      Classification: 32c