J. Strait Pharm. 24 (5), 36-38 (2012). Glucosamine sulfate is a kind of glycosaminoglycan, which, as a medicine, is able to stimulate cartilage cells, to supplement the cartilage matrix and to inhibit matrix metalloproteinase expression, thus to promote the repair of cartilage. For better quality control of the medicine a method is presented for the analysis of the related substances in glucosamine sulfate potassium chloride. TLC on silica gel with dichloromethane – methanol – ammonia 2:2:1, detection by exposure to iodine vapors for 30 min and evaluation in daylight. The LOD was 25 µg/mL. Investigation of the stability of the medicines by analysis of a sample submitted to typical stress conditions such as acid, alkali, water bath, hydrogen peroxide, high temperature and UV light. Degradation occurred only for the samples treated with alkali and in the water bath.

CBS 116, 9-10 (2016). HPTLC of herbal slimming drugs and the standard orlistat on silica gel with toluene – ethyl acetate 4:1 with chamber saturation (with filter paper) to the migration distance of 70 mm. Detection by dipping in phosphomolybdic acid reagent (5 g in 100 mL ethanol) and heating at 110 °C for 5 min. Evaluation under UV 254 nm, 366 nm and white light. Quantitative determination by absorbance measurement at 195 nm before derivatization to detect illegally added orlistat in the herbal drugs. The LOD of orlistat standard was 70 ng/band.

J. Planar Chromatogr. 31, 112-115 (2018). HPTLC of topiramate in human serum on silica gel with toluene – ethanol 9:1. Detection by derivatization with a 30 mg/mL solution of phenol in ethanol – sulfuric acid 19:1, followed by heating at 120 °C for 15 min. Quantitative determination by absorbance measurement at 417 nm. The hRf value for topiramate was 37. The calibration curve was constructed in the range of 0.25-40 μg/zone. The intermediate precision was below 4.2 % (n=6). The LOD and LOQ were 360 and 1100 ng/zone. Recovery was between 97.4 % and 110.7 %.

J. Chromatogr. 342, 458-464 (1985). TLC of pindolol on silica with chloroform - methanol - acetic acid 75:20:5. Detection by a) dipping into 4 % paraffin in cyclohexane, b) spraying with o-phthaldialdehyde reagent and heating at 40-50 °C for 10 min. Quantification by fluorescence densitometry. Nadolol was used as the internal standard.

Quantification by densitometry at 315 nm.

Chinese J. Med. Ind. 18, 266-267 (1987) (Yiyao Gongye). TLC of nifedipine and its analogs, nitrendipine and nimodipine on silica with hexane - chloroform - ethyl acetate 2:3:1 or hexane - acetone 1:1. Identification by Rf comparison and UV spectroscopy.

Chinese J. Pharm. Anal. 8, 196-200 (1988) (Yaowu Fenxi Zazhi). Application of six Chinese traditional patent formulations without pretreatment, on silica by TAS technique. Development with various solvent systems. Detection by spraying with various reagents.

J. Chromatogr. 456, 435-439 (1988). TLC on silica with dioxane - isopropanol - 25% NH3 - toluene - xylene 3:3:2:1:1. Quantification by densitometry at 254 nm. R.S.D. 1.9%.