Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
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      113 039
      Screening and determination of sibutramine in adulterated herbal slimming supplements by
      HPTLC-UV densitometry
      Caroline MATHON, Anita ANKLI, E. REICH, S. BIERI, P. CHRISTEN* (*School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Quai Ernest-Ansermet 30, 1211 Geneva 4, Switzerland, Philippe.Christen@unige.ch)

      Food Addit. Contam. 31, 15-20 (2014). HPTLC of sibutramine in food supplements and soluble beverages on silica gel with toluene - methanol 9:1. Quantitative determination by absorbance measurement at 225 nm. The hRF value for sibutramine was 53. Linearity was in the range of 78-3020 ng/zone. The method was sensitive to detect 0.3 mg of sibutramine per capsule of food supplement and showed comparable results with those obtained with HPTLC-UV and HPLC-MS.

      Classification: 17c
      113 087
      Validated stability-indicating HPTLC method for the determination of propafenone hydrochloride in tablets and the GC-MS identification of its degradation products
      R. PIETRAS*, D. KOWALCZUK, E. RUTKOWSKA, L. KOMSTA, A. GUMIENICZEK (*Department of Medicinal Chemistry, Faculty of Pharmacy, Medical University of Lublin, 20-090 Lublin, Poland, rafal.pietras@umlub.pl)

      J. Planar Chromatogr. 27, 2942-2955 (2014). HPTLC of propafenone hydrochloride in tablets on silica gel with chloroform - methanol - acetic acid 79:20:1. Quantitative determination by absorbance measurement at 316 nm. The hRF value for propafenone hydrochloride was 64. Linearity was in the range of 100-3200 ng/zone. The intermediate/interday/intra-day precisions were below 2 % (n=3). The LODs and LOQs were 20 and 80 ng/zone, respectively. Recoveries were between 99.5 and 102.2 %.

      Classification: 32e
      115 061
      Comparative study of reversed-phase high-performance liquid chromatography versus thin-layer chromatography-densitometry for determination of citicoline sodium in presence of its alkaline degradation products
      Omnia A. MAHMOUD*, Maha A. HEGAZY, H. SALEM, Azza A. MOUSTAFA (*Analytical Chemistry Department, Faculty of Pharmacy, October University for Modern Sciences and Arts (MSA), 11787 6th October City, Egypt, dr.omniali@gmail.com)

      J. Planar Chromatogr. 28, 241-247 (2015). TLC of (1) citicoline sodium in the presence of its (2) alkaline degradation products in pharmaceutical oral solution on silica gel with ammonia - ethyl acetate - triethylamine 12:7:1. Quantitative determination by absorbance measurement at 272 nm. The hRF value was 35 for (1) and 10 for (2). Linearity for (1) was between 0.6 and 2.2 µg/zone. The intraday precision was 0.2 % and interday precision was 1.2 % for (1). The LOD and LOD of (1) were 41 ng/zone and 237 ng/zone, respectively.

      Classification: 2f, 32b
      117 131
      HPTLC-MS combined with H/D exchange for the identification of substances in environmental analysis
      S.C. WEISS*, W. SCHULZ, A. MUELLER, W.H. WEBER (*Zweckverband Landeswasserversorgung, Betriebs- und Forschungslaboratorium, Am Spitzigen
      Berg 1, 89129 Langenau, Germany, weiss.s@lw-online.de)

      CBS 113, 5-7 (2014). HPTLC/AMD as a screening method to identify previously unconsidered_x000D_
      substances. HPTLC of water samples on silica gel LiChrospher in the AMD 2 with a 25-step gradient, starting in the isocratic mode with 5 steps acetonitrile – dichloromethane 1:1 for focusing, followed by 15 steps from acetonitrile – dichloromethane 1:1 to dichloromethane and then 5 steps from dichloromethane – n-hexane 4:1 to n-hexane. Final migration distance 80 mm. Detection under UV 254 nm, UV 366 nm and white light. Densitometric evaluation by absorbance measurement at 190, 200, 220, 240, 260, 280, and 300 nm. Target zones were eluted with the TLC-MS Interface offline with water – acetonitrile 1:1 and deuterium oxide – acetonitrile 1:1, respectively, each with an addition of 5 mmol/L ammonium acetate, at a flow rate of 0.2 mL/min using the oval elution head (4 x 2 mm) for analysis with a QTOF/MS. With the molecular formula information, different databases were searched and H/D exchange (replacing protons in the molecule by deuterium which leads to a mass shift in the ESI MS spectra) was used to reduce the quantity of possible structures.

      Classification: 37c
      120 056
      Quantification of bitter acids in hops
      M. SCHULZ*, M. BURHOLT, J. ENGELMANN, H. GRIESINGER, M. OBERLE, V. PILAKOWSKI (*Merck KGaA, Frankfurter Str. 250, 64293 Darmstadt, Germany, michael.schulz@merckgroup.com)

      CBS 119 (2017 12-13. HPTLC of hop extracts on silica gel (MS-grade) by automated multiple development using a 9-step AMD 2 gradient based on ethyl acetate – methanol – n-heptane. Quantitative determination by fluorescence measurement at 360/>400 nm with the deuterium lamp. The hRF of α-acids was 36 and of β-acids 65 and the matrix was well separated. With this study the differences in the bitter acid content of regional and varietal hops was determined. In most cases, the bitter hops contained more bitter acids than aromatic hops.

      Classification: 11a
      121 063
      Immunological analysis of food proteins using high-performance thin-layer chromatography-immunostaining
      L. MORSCHHEUSER, K. MINK, R. HORST, C. KALLINICH, S. ROHN* (*Univ. of Hamburg, Hamburg Sch. of Food Sci., Inst. of Food Chem., Grindelallee 117, 20146 Hamburg, Germany, rohn@chemie.uni-hamburg.de)

      J. Chromatogr. A 1526, 157-166 (2017). Introduction of a promising alternative method for protein analysis using HPTLC with its high level of variability regarding the chromatographic system (multiple mobile and stationary phases, even mixed) and manifold detection as well as hyphenation possibilities. Silica gel, cellulose, and different RP layers were investigated with regard to their applicability for HPTLC-immunostaining. HPTLC of intact proteins on silica gel with 2-butanol – pyridine – ammonia – water 39:20:10:31; on cellulose with 2-butanol – pyridine – ammonia – water 32:30:11:25; and on RP phase with acetonitrile – trifluoroacetic acid – water 400:30:37. After development the plate was incubated with Tween20 as blocking reagent in a small vessel to inhibit unspecific binding of the antibodies to the surface. Then the plate was incubated for 2 h with the primary antibody solution and after washing with the secondary antibody for 1 h. Detection by incubating the plate in a dying solution containing 0.06% 3,3',5,5'-tetramethylbenzidine, 0.2% dioctyl sulfosuccinate sodium salt, 0.7% citric acid monohydrate, 1.8% sodium hydrogen phosphate dihydrate, 25% ethanol, and 1.5‰ dihydrogen dioxide, until blue zones appeared under white light. For the example analysis of beta-lactoglobulin on silica gel using antibovine beta-lactoglobulin antibodies, linearity was in the range of 75-2000 ng, the LOD was 62 ng/zone, the LOQ 93 ng/zone, and the accuracy 98.3%.

      Classification: 18b, 19
      55 014
      Special fine-particle alumina chromatoplate for HPTLC and OPLC
      L. ZSEMBERY, A. MATHUNY, Z. CSILLAG, G. KEMENY, E. MINCSOVICS

      Proc. Intern.Symposium on TLC with special emphasis on OPLC, Szeged, 107 (1984). OPLC (OPTLC) of a dye mixture on alumina with toluene.

      Classification: 3b
      55 090
      OPLC of diethyl-dithicoarbamate-metal chelates and its use in the pharmaceutical analysis
      K. FERENCZI-FODOR, Z. VEGH, G. SZEPESI

      Proc. Intern.symposium on TLC with special Emphasis on OPLC, Szeged, 29 (1984). OPLC (OPTLC) of 15 diethyl-dithiocarbamate-metal chelates on silica with chloroform - dichloromethane 6:4. Densitometric scanning by absorbance.

      Classification: 26a
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