Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
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      107 157
      How to suppress the spontaneous oscillatory in-vitro chiral conversion of a-substituted propionic acids? A thin-layer chromatographic, polarimetric, and circular dichroism study of complexation of the Cu(II) cation with L-lactic acid
      M. SAJEWICZ*, E. JOHN, D. KRONENBACH, M. GONTARSKA, M. WRÓBEL, T. KOWALSKA (*Silesian University, Inst. of Chem., 9 Szkolna Street, 40-006 Katowice, Poland)

      Acta Chromatographica 21(1), (2009) . This study focused on the attempt to suppress the spontaneous oscillatory in-vitro chiral conversion of a-substituted propionic acids using, as example, L-lactic acid dissolved in water in the presence of copper(II) cations to check whether the coordinate covalent bonds between copper(II) and L-lactic acid ligands prevented the latter species from oscillatory chiral conversion. Aqueous solutions of copper(II) acetate and lactic acid in the molar ratios 1:1, 1:2, and 1:3 were stored and the possible chiral conversion of L-lactic acid was monitored by TLC, polarimetry, and circular dichroism spectroscopy. It was found that chelating of copper(II)cations with L-lactic acid did not result in suppression of the spontaneous oscillatory in-vitro chiral conversion of the acid from the TLC data. Different molar proportions of copper(II) cation and L-lactic acid had somewhat different effects on the dynamics of conversion, in contrast, when L-lactic acid is dissolved in water in the presence of copper(II)cations almost no chiral conversion is observed from polarimetric and circular dichroism studies. It was therefore concluded that chelating of copper(II) cations with L-lactic acid stabilizes the chiral structure of the acid in solution. The structure-stabilizing effect of copper(II) cations is weakened by the TLC system due to the interaction of the copper(II)-L-lactic acid complex with the silica gel.

      Classification: 38
      108 037
      The effect of a diapause on neutral lipids in the pitcher-plant mosquito Wyeomyia smithii as determined by HPTLC-densitometry
      J.L. COUNIHAN, K.E. HUEGLIN, C.R. WAGNER, S. P. GADOMSKI, P.A. ZANI, B. FRIED*, J. SHERMA (*Department of Biology, Lafayette College, Easton, PA, USA 18042; friedb@lafayette.edu)

      J. Planar Chromatogr. 24, 206-210 (2011). HPTLC of free sterols, free fatty acids, triacylglycerols, methyl esters, and steryl esters in larvae samples on silica gel with concentration zone, with petroleum ether - diethyl ether - glacial acetic acid 80:20:1 in a twin-trough chamber saturated for 20 min at 21 +/- 1 °C and a relative humidity of 25 %. Detection by spraying with 5 % ethanolic phosphomolybdic acid solution. Quantitative determination by densitometry at 610 nm.

      Classification: 11c
      108 071
      A validated HPTLC method for the determination of illegal dyes in spices and spice mixtures
      H. KANDLER, M. BLEISCH, Valeria WIDMER, E. REICH* (*CAMAG Laboratory, Sonnenmattstrasse 11, 4132 Muttenz, Switzerland, eike.reich@camag.com)

      J. Liq. Chromatogr. Relat. Technol. 32, 1273-1288 (2009). HPTLC of Sudan I (1), II (2), III (3), IV (4), Sudan Red B (5), Sudan Red 7B (6), Sudan Red G (7), Para Red (8), FD&C Orange 2 (9), Butter Yellow (10), Citrus Red 2 (11), Toluidine Red (12), and Disperse Orange 11 (13) in paprika, chili, and curry on RP-18 with acetonitrile - ammonia 25 % 19:1. Quantitative determination by absorbance measurement at absorption maxima of each dye. The hRf values of compounds (1) - (13) were 61, 54, 48, 29, 18, 11, 69, 63, 56, 48, 39, 18 and 11, respectively. Visual detection limits were 3 ppm for most dyes in either matrix, 5 ppm for Sudan I, 13 ppm for Disperse Orange, and 7 ppm for Butter Yellow. The limits of detection by densitometry were lower by a factor of 2 for all dyes and values of 1-3 ppm were reached except for Disperse Orange with a limit of detction of 7 ppm. Average recoveries ranged from 95.0-110.8 %. The HPTLC method is successfully applied in the routine control of illegal dyes in food by surveillance authorities.

      Classification: 30a
      108 102
      Validated HPTLC method for simultaneous quantitation of paracetamol, diclofenac potassium, and famotidine in tablet formulation
      L.D. KHATAL, A.Y. KAMBLE, M.V. MAHADIK, S. DHANESHWAR* (*Bharati Vidyapeeth University, Poona College of Pharmacy, Department of Pharmaceutical Chemistry, Pune, Maharashtra, India 411038; sunil.dhaneshwar@gmail.com)

      J. AOAC Int. 93, 765-770 (2010). HPTLC of paracetamol (PAR), diclofenac potassium (DCL), and famotidine (FAM) on silica gel (prewashed with methanol) with toluene - acetone - methanol - formic acid 500:200:200:1 in a twin-trough chamber after preconditioning for 30 min at room temperature (25 +/- 2°C ) at a relative humidity of 60 +/- 5 %. Quantitative determination by absorbance measurement at 274 nm. The hRf value of paracetamol was 62, of diclofenac potassium 75, and of famotidine 17. Linearity was between 1625-9750 ng/zone for PAR, 250-1500 ng/zone for DCL, and 100-600 ng/zone for FAM. The %RSD values for repeatability and intermediate precision were below 2 %. The LOD and LOQ were 50 and 100 ng/zone for PAR and DCL, and 10 and 50 ng/zone for FAM. The %RSD of peak areas was calculated for each parameter and was found to be less than 2 %. Recoveries (by standard addition) were in the range of 95-98 % at various added concentrations.

      Classification: 32a
      108 126
      Characterisation of cultivars of Jamaican ginger (Zingiber officinale Roscoe) by HPTLC and HPLC
      C. SALMON*, Y. SHAW, S. HIBBERT, C. GREEN, A. SMITH, L. WILLIAMS (*Scientific Research Council, Hope Complex, P.O. Box 350, Kingston 6, Jamaica, colleens@src-jamaica.org)

      Food Chemistry 131, 1517-1522 (2012). HPTLC fingerprinting of 6-gingerol (1), 8-gingerol (2), 10-gingerol (3) and 6-shogaol (4), in the rhizome of Jamaican ginger (Zingiber officinale Roscoe) on silica gel with hexane - ethyl acetate - formic acid 11:8:1. Detection by spraying with either 5 % ammonium molybdate in 10 % sulfuric acid, or 0.5 mL p-anisaldehyde in 50 mL glacial acetic acid and 1 mL 97 % sulfuric acid. Quantitative determination by densitometry at 366 nm. The hRf values of (1) - (4) were 46, 49, 52 and 64, respectively. This method of chemical fingerprinting is a suitable analysis for rapid determination of the authenticity of the ginger product as a chemical composite.

      Classification: 32e
      109 012
      TLC-MS versus TLC-LC-MS fingerprints of herbal extracts, Part II) Phenolic acids and flavonoids
      M. SAJEWICZ, D. STASZEK, M. NATIC, L. WOJTAL, Monika WAKSMUNDZKA, Teresa KOWALSKA* (*Institute of Chemistry, University of Silesia, 9 Szkolna, Street, 40-006 Katowice, Poland, teresa.kowalska@us.edu.pl)

      J. Liq. Chromatogr. Relat. Technol. 34, 864-887 (2011). Comparison of a one dimensional TLC-MS separation and fingerprinting method with a two-dimensional TLC-LC-MS method, when applied to the analysis of phenolic acids and flavonoids from Salvia lavandulifolia. TLC directly or indirectly coupled with mass spectrometric detection proved very useful in the analysis of the phenolic acid and flavonoid fraction selectively extracted from botanical material.

      Classification: 4e
      109 038
      High-performance thin-layer chromatographic determination of spironolactone and torsemide in combined tablet dosage form
      N. GAIKWAD*, P. DESHPANDE, S. GANDHI, K. KHANDAGALE (*Dept. of Pharmaceutical Analysis, AISSMS College of Pharmacy, Kennedy Rd.,Pune, India, santoshvgandhi@rediffmail.com)

      Research J. Pharm. and Tech. 3(4), 1106-1108 (2010). TLC of spironolactone and torsemide in combined tablet dosage form on silica gel with n-hexane - ethyl acetate - methanol - glacial acetic acid 12:6:3:1. Quantitative evaluation by absorbance measurement at 263 nm. The hRf value of spironolactone and torsemide was 67 and 34, respectively. The linearity was in the range of 100-1000 ng/band for both drugs. The method has been successfully applied for the analysis of drugs in pharmaceutical formulation.

      Classification: 17c
      109 056
      Stability-indicating HPTLC method for analysis of ticlopidine in pharmaceutical preparations
      R. KAKDE*, A. BARSAGADE, N. CHAUDHARY, D. KALE (*Department of Pharmaceutical Sciences, R. T. M. Nagpur University, Amravati Road, Nagpur-440033, Maharashtra, India;drkakde@yahoo.com)

      J. Planar Chromatogr. 24, 145-149 (2011). HPTLC of ticlopidine in the bulk drug and dosage form on silica gel, prewashed with methanol, with toluene - methanol 49:1. Quantitative determination by absorbance measurement at 240 nm. The hRf of ticlopidine was 60. Linearity was in the range 800-1500 ng/zone; the correlation coefficient was 0.999. LOD was 35 and 0.2 ng/band by peak height and peak area, respectively. Recovery was 98.5 % and 99.1 % by peak height and peak area, respectively. The inter-day and intra-day precision (%RSD, n = 3) was 0.9 % and 0.4 % via peak height and 0.6 % and 0.4 % via peak area.

      Classification: 24
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