Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
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      81 117
      Detection of 1,4-benzodiazepines and benzophenones with a secondary amino group by thermal conversion and diazotization and spraying with Bratton-Marshall reagent
      K. VOLF, (Dept. of Clin. Biochem., Hospital Kladno, Vancurova Street, 272 01 Kladno, The Czech Republic)

      J. Planar Chromatogr. 11, 132-136 (1998). HPTLC of fourteen 1,4-benzodiazepines (diazepam, bromazepam, dipotassium chlorazepate, chlordiazepoxide, clonazepam, flurazepam flunitrazepam, nitrazepam, medazepam, lormetazepam, oxazepam, prazepam, temazepam, tofisopam; clobazam, midazolam, triazolam, alprazolam, clotiazepam) on silica gel with chloroform - acetone 4:1and benzene. After thermal treatment the Bratton - Marshall diazotization reaction can be used for the detection of benzodiazepines (BZ) and benzophenones when the substituent is a secondary amino group. Thermal treatment alone also gives color reactions with some BZ, and in combination with Bratton-Marshall reagent and the Rf values of the drugs serves as a specific method of identification of various BZ.

      Classification: 32a
      83 140
      In-process control and process parametric assessment of isosorbide 5-mononitrate pharmaceuticals
      J. NAVAKOVIC*, H. NOVA, K. FILKA, (PRO.MED.CS, Telcsk· 1, 141 00 Prague 4, The Czech Republic)

      J. Planar Chromatogr. 12, 161-164 (1999). HPTLC of isosorbide mononitrate on silica gel with chloroform - methanol - acetic acid 270:30: 1. Evaluation by densitometry in absorbance mode at 200 nm. The HPTLC method for determination of IS-5-MN in pharmaceuticals has been fully validated and applied successfully for process-parameter assessment and in-process monitoring of Monosan tablets. Terfenadine was used as the internal standard. Large sample throughput, small solvent consumption, and robustness in terms of in situ analyte stability and applied volumes are the main advantages of the HPTLC method. System suitability results indicate that the method could be used for impurity and stability testing of IS-5-MN when IS-2-MN and ISDN (isosorbide dinitrate) are considered as impurities.

      Keywords:
      Classification: 32a
      84 113
      Quantitative HPTLC determination of salicylic acid in topical acne medications
      J.R. McLAUGLIN, J. SHERMA, (Dept. of Chem., Lafayette Colleg, Easton, Pennsylvania 18042-1782, USA)

      J. Liq. Chrom. & Rel. Technol.19, 17-21 (1996). HPTLC of salicylic acid on silica gel with n-pentyl formate - chloroform - formic acid 2:7:1. Detection under UV 254 nm; quantitation by densitometry in the single-beam reflectance mode. Variation coefficients for the analyses was 3.9 and 5.6 %, respectively.

      Keywords:
      Classification: 32a
      85 118
      Determination of the lipophilicity of carbonyl derivatives of 2-aminoimidazolines-2 by reversed-phase thin-layer chromatography
      D. MATOSIUK*, K JOZWIAK, (*Dept. of Synth. and Techn. of Drugs, Fac. of Pharm., Med. Univ., Staszica 6, 20-081 Lublin, Poland)

      Part 1. Lipophilicity of 1-(1-arylimidazolin-2-yl)-3-arylureas and 1-aryl-2-imine-3-arylaminocarbonylimidazolidines. J. Planar Chromatogr. 13, 52-56 (2000). Determination of the lipophilicity of forty new derivatives of 1-aryl-2-aminoimidazolines (twenty 1-(1-arylimidazolin-2-yl)-3-arylureas and twenty 1-aryl-1-2-imine-3-arylaminocarbonyl-imidazolidines) by RP-TLC with methanol - acetic acid - water. Visualization under UV at 254 nm.

      Keywords:
      Classification: 32a
      87 145
      Rapid screening of indole-3-acetic acid and other indole derivatives in bacterial culture broths by planar chromatography
      T. YRJ÷NEN, J.P. HAANSUU, K. HAAHTELA, H. VUORELA, P. VUORELA*, (*Viikki Drug Discovery Techn. Center, Dept. of Pharm., P.O. Box 56 (Viikinkaari 5 E), FIN-00014 Univ. of Helsinki, Finland)

      J. Planar Chromatogr. 14, 47-52 (2001). TLC and rotation planar chromatography (RPC) of 17 indol derivatives on silica gel with acetic acid - ethyl acetate - toluene - hexane 4:11:70:15. The PRISMA system was used in pre-assays to optimize mobile-phase composition. Another mobile phase used was chloroform - ethyl acetate - formic acid 5:4:1. Quantitation by densitometry at 280 nm.

      Keywords:
      Classification: 32a
      89 131
      Simultaneous densitometric determination of indomethacin and its degradation products, 4-chlorobenzoic acid and 5-methoxy-2-methyl-3-indoleacetic acid, in pharmaceutical preparations
      J. KRZEK, M. STAREK, (Jagiellonian Univ., Collegium Medicum, Dept. of Inorg. and Anal. Chem., 9 Medyczna St, 30-699, Krakow, Poland)

      JAOAC Int. 84, 1703-1707 (2001). TLC of indomethacin, 4-chlorobenzoic acid, and 5-methoxy-2-methyl-3-indoleacetic acid on silica gel with 2-propanol - 25% NH3 - water 8:1:1. Detection under UV 268, 236 and 292 nm. Simultaneous determination of both impurities by densitometry at 230 nm and at 284 nm for indomethacin.

      Keywords:
      Classification: 32a
      89 162
      TLC determination of acyclovir in pharmaceutical preparations, and validation of the method used
      T.K. SIA, L. WULANDARI, G. INDRAYANTO*, (*Lab. of Pharm. Biotechn., Fac. of Pharm., Airlangga Univ., Jl. Dharmawangsa dalam, Surabaya 69286, Indonesia)

      J. Planar Chromatogr. 15, 42-45 (2002). TLC of acyclovir (9-[(2-hydroxyethoxy)methyl]guanine) on silica gel with n-butanol - acetic acid - water 5:3:2. Densitometry in absorbance-reflectance mode at 277 nm. The method was validated for linearity, homogeneity, detection limit, accuracy (100.2 to 101.5%), and range. Simple, rapid, cheap and validated TLC method.

      Keywords:
      Classification: 32a
      90 127
      New visualizing reagents for selected phenolic drugs investigated by thin layer chromatography
      A. PYKA*, D. GURAK, K. BOBER, (*Fac. of Pharm., Silesian Acad. of Med., 4 Jagiellonska Street, PL-41-200 Sosnowiec, Poland)

      J. Liq. Chrom. & Rel. Technol. 25, 1483-1495 (2002). TLC of phenolic drugs (methyldopa, norepinephrine, terbutaline, bamethane, ethamivan, phloroglucinol, pentazocine, hexachlorophene, pyrocatechine, niclosamide, salicylanilide, thymol, eugenol) on silica gel with acetic acid - n-butanol - water 1:4:1, chloroform - methanol 9:1 and with benzene. 13 detection agents (e.g. alkaline blue, aniline blue, bromophenol blue, bromothymol blue, alkaline solution of brilliant cresyl blue, bromocresol green, helasol green, aqueous solution of brilliant cresyl blue, neutral red, phenol red) were tested; aniline blue and brilliant green were the best and most universal visualizing reagents for the phenolic drugs investigated.

      Keywords:
      Classification: 32a
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