Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
  • Browse and search by CBS classification: Select one of the 38 CBS classification categories where you want to search by a keyword
  • Keyword register: select an initial character and browse associated keywords
  • Search by CBS edition: Select a CBS edition and find all related publications

Registered users can create a tailor made PDF of selected articles throughout CCBS search – simply use the cart icon on the right hand of each abstract to create your individual selection of abstracts. You can export your saved items to PDF by clicking the download icon.

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      112 091
      (Study on the method for the quality control of Fufang Kuhuang Penwu spray by thin-layer chromatography) (Chinese)
      L. LIU (Liu Longyou), Q. CHEN (Chen Qingyan), Y. TANG (Tang Yingshuang)* (PLA No. 68306 Hosp., Shanxi, Xian 710600, China)

      Chinese J. of Med. Guide 18 (12), 82-84 (2012). Fufang Kuhuang Penwu spray is a herbal TCM preparation for treatment of eczema, skin itch and solar dermatitis. For quality control, TLC on silica gel 1) for borneol, with cyclohexane – ethyl acetate 33:7, detection by spraying with 1 % vanillin in sulfuric acid – ethanol 1:4, heating at 105 °C until the zones are visible in daylight; 2) for Cortex Phellodendri Chinensis and the standard berberine hydrochloride, with benzene – ethyl acetate – methanol – isopropanol – concentrated ammonia 12:6:3:3:1, detection under UV 366 nm; 3) for Rheum palmatum L., Reynoutria japonica Houtt, and the standard emodin, with petroleum ether (30-60 °C) – ethyl formate – formic acid 15:5:1, detection under UV 366 nm before and after exposure to ammonia vapors.

      Classification: 32c
      118 090
      Stability-indicating HPTLC method for simultaneous estimation of flurbiprofen and chloramphenicol in ophthalmic solution
      V.M. SADAKWALA*, R.S. CHAUHAN, S.A. SHAH, D.R. SHAH (*Dep. of Qual. Assur., Maliba Pharm. Coll., Uka Tarsadia Univ., Bardoli 394 350, Distr. of Surat, Gujarat, India, vaishnavisadakwala@gmail.com)

      J. Chromatogr. Sci. 54 (1), 70-78 (2016). HPTLC of flurbiprofen and chloramphenicol in the presence of their degradation products, produced in acidic, alkaline, neutral, oxidative, photolytic and thermal stress conditions, on silica gel with ethyl acetate – n-hexane – methanol – triethylamine 10:8:4:1. The hRf of flurbiprofen was 29 and of chloramphenicol 62. Quantitative determination by densitometry at 267 nm. Linearity was between 12 and 60 ng/zone with a correlation coefficient of 0.9997 for flurbiprofen and between 200 and 1000 ng/zone with a correlation coefficient of 0.9977 for chloramphenicol. The application of the method to the estimation of flurbiprofen and chloramphenicol in commercial ophthalmic formulation indicated that the method was specific, accurate, reproducible and suitable for routine analysis of flurbiprofen and chloramphenicol in the presence of their degradation products in their individual as well as combined pharmaceutical formulations.

      Classification: 32c
      122 023
      eicCluster software, an open-source in silico tool, and on-surface syntheses, an in situ concept, both exploited for signal highlighting in high-resolution mass spectrometry to ease structure elucidation in planar chromatography
      D. FICHOU, I. YÜCE, Gertrud MORLOCK* (*Justus Liebig Univ. of Giessen, Inst. of Nutrit. Sci., Chair of Food Sci., & Interdiscipl. Res. Center, Heinrich-Buff-Ring 26-32, 35392 Giessen, Germany, Gertrud.Morlock@uni-giessen.de)

      J. Chromatogr. A 1577, 101-108 (2018). In order to overcome the difficulty of the interpretation of the MS signals present at a low intensity for unknown degradation products or impurities, a new strategy and open-source software called eicCluster was developed. It offered unsupervised machine learning algorithms and powerful interactive visualization tools that made data processing fast and intuitive. The low-intensity HPTLC-HRMS signals were highlighted in a stressed formulation by using eicCluster. Thus, even compound ions present at low intensities were separated in subclusters from background signals (in silico highlighting). The respective preprocessing led to intensity-agnostic signals and the t-SNE algorithm clustered mass signals based on their similarity. The resulting 2D maps allowed a new view on the data set to such low-intensity target molecules in complex mixtures. Moreover, the targeted on-surface synthesis of degradation products (in situ highlighting) was shown to support a fast structure elucidation, when standards are not commercially available. It allowed a better understanding of the proposed degradation reactions in the formulation. Comparison with the results of stressed samples as well as the proposed degradation products of on-surface synthesis proved that in silico and in situ signal highlighting substantially eased structure elucidation and data processing.

      Classification: 3e, 4e, 32c
      57 166
      Thin-layer chromatographic identification and quantification of niacin and niacinamide in pharmaceutical preparations
      B. SARANGI, S.K. CHATTERJEE, K. DUTTA, S.K. DAS

      J.A.O.A.C. 68, 547-548 (1985). TLC of niacin and niacinamide on silica with water. Detection by UV at 254 nm. Quantification after elution with 0.1 N HCl by spectrophotometry at 262 nm.

      Classification: 32c
      59 193
      Quantitative thin-layer chromatography in accelerated stability studies for prediction of inherent sensitivity of drugs toward oxygen
      L. R. TREIBER

      J. Chromatogr. 370, 139-147 (1986). TLC of numerous drugs on silica with ethyl acetate, except with estradiol which was separated with chloroform - dioxane 9:1. After development, the plates were transferred into a closed chamber for drying in a stream of nitrogen, under complete exclusion of oxygen. The quantitative evaluation was carried out at the wavelength corresponding to the absorption maximum for the compound being tested. Plots of the recoveries against the respective exposure times allowed the construction of kinetic curves describing the accelerated decomposition process.

      Classification: 32c
      62 085
      Determination of chenodeoxycholic acid on 3-cyanopropyltrichlorosilane-treated high-performance thin- layer chromatographic plates
      M. OKAMOTO, H. KAKAMU, T. OMORI, (Gifu Pretect. Tajimi Hosp., Tajimi, Japan 507)

      Chromatographia 23, 601-603 (1987). HPTLC on cyanoalkyl- bonded silica with methanol. Quantification by densitometry at 370 nm. Detection limit, 30 ng.

      Classification: 11a, 32c
      63 175
      Liquid chromatographic determination of tetracycline residues in animal feed
      E.E. MARTINEZ, W. SHIMODA, (Food & Drug Adminis., Animal Drug Res. Cent., Denver Fed. Cent., Denver, CO 80225, USA)

      J.A.O.A.C. 71, 477-480 (1988). Confirmation of the identities of tetracyclines from LC fractions by TLC with acetonitrile - dichloromethane - isopropanol - 10% aqueous EDTA tetra sodium salt 65:10:15:10. Detection under UV.

      Classification: 32c
      64 286
      Screening, conformation and quantification of boldenone sulfate in equine urine after administration of boldenone undecylenate (Equipoise)
      L.O. WEIDOLF, T.M.P. CHICHILA, M.P. TINA, J.D. HENION* (New York State Coll. Vet. Med., Cornell Univ., Ithaca NY 14850, USA)

      J. Chromatogr. 433, 9-21 (1988). TLC on silica with ethyl acetate - acetic acid 39:1. Detection under UV 254 nm or by spraying with vanillin - concentrated sulfuric acid 1:99.

      Classification: 32c
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