Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
  • Browse and search by CBS classification: Select one of the 38 CBS classification categories where you want to search by a keyword
  • Keyword register: select an initial character and browse associated keywords
  • Search by CBS edition: Select a CBS edition and find all related publications

Registered users can create a tailor made PDF of selected articles throughout CCBS search – simply use the cart icon on the right hand of each abstract to create your individual selection of abstracts. You can export your saved items to PDF by clicking the download icon.

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      63 155
      Antihypertensive activity in a series of 1-piperazino-3-phenylindans with potent 5-HT2-antagonistic activity
      K.P. BOGESO*, J. ARNT, V. BOECK, A.V. CHRISTENSEN, J. HYTTEL, K.G. JENSEN, (*Research Lab., H. Lundbeck A/S, Ottiliavej 7-9, DK-2500 Copenhagen-Valby, Denmark)

      J. of Medicinal Chemistry 31, 2247-2256 (1988). TLC of cis and trans isomers on silica with acetone - toluene - NH3 - 2-propanol 60:40:2:2. Visualization by spraying the dried plate with a mixture of concentrated sulfuric acid - 37% formaldehyde solution 47:3, heating for 5 min. at 110°C and inspection under UV 365 nm.

      Classification: 32a
      64 260
      Binary antidotes for organophosphate poisoning
      H. LAEDER*, R.M. SMEJKAL, C.S. PAYNE, F.N. PADILLA, B.P. DOCTOR, R.K. GORDON, P.K. CHIANG, (*Dep. of Applied Biochem., Walter Reed Army Inst. of Res., Washington, DC 20307-5100, USA)

      J. of Medicinal Chemistry 32, 1522-1528 (1989). TLC of aprophen analogues on silica with chloroform - methanol 95:5. Visualization under UV and by exposing to iodine vapor.

      Classification: 32a
      66 159
      Radiosynthesis of (14C) acarbose
      W. MAUL, L. MÜLLER, J. PFITZNER, E. RAUENBUSCH, H. SCHUTT, (Pharma Res. Center, Bayer AG, Wuppertal, Germany)

      Arzneim.-Forsch. 39, 1251-1253 (1989). TLC on silica with different solvent systems, 1) butanol – ethanol – water 90:70:40, 3-fold development over 15 cm each time, 2) ethyl acetate – methanol – water – pyridine 80:80:40:2, single development. Detection by spraying with a solution of 0.5 g thymol in ethanol – sulfuric acid conc. 95:5 and heating at 120 °C for 15-20 min. Determination of radiochemical purity with two-dimensional TLC on cellulose with acetone – water 70:30.

      Classification: 32a
      68 182
      Quantitative HPTLC determination of cyproterone acetate and ethynyl estradiol in pharmaceuticals
      J. NOVAKOVIC, I. NEMCOVA*, M. VASATOVA, (*Fac. of Natural Sci., Dept. of Anal. Chem., Charles Univ., Albertov 2030, 12840 Prague 2, Czechoslovakia)

      J. Planar Chromatogr. 3, 407-409 (1990). HPTLC of cyproterone acetate and ethynyl estradiol on silica with cyclohexane - ethyl acetate 6:4 as mobile phase and 17ß-estradiol as internal standard. quantification by densitometry (absorbance at 284 nm). Detection limit for cyproterone acetate was 5 ng, for ethynyl estradiol 30 ng. The relationship between the spot concentration and the cyproterone acetate 17ß-estradiol area ration was linear over a range of 5 to 120 ng; for ethynyl estradiol the linear range was 120 to 1200 ng. The proposed assay is suitable for routine drug control.

      Classification: 32a
      70 203
      Identification and determination of polidocanol in a suppository formulation
      B. KRUMHOLZ, K. WENZ*, (*Dept. of Qual. Control, Asta Medica AG, D-W-6000 Frankfurt, Germany)

      J. Planar Chromatogr. 4, 370-372 (1991). HPTLC of polidocanol (mixture of monolauryl ethers of polyethylene glycols) on silica with MEK - acetone 10:1, water saturated. Visualization by dipping the plates for one second into a solution of 2% potassium dichromate in 12% aqueous sulfuric acid. Quantification by densitometry in reflectance mode at 600 nm. CV =3.4% (n=10) and recovery rate 97.0 + 3.1% (n=8).

      Classification: 32a, 35c
      74 126
      Einfache dünnschichtchromatographische Identifitätsprüfung in Fertigarzneimitteln
      P. PACHALY, G. RADAU, (Pharm. Inst. der Rhein. Friedrich-Wilhelms-Universität Bonn, Kreuzbergweg 26, D-53115 Bonn)

      - Simple thin-layer chromatographic identification of active principles in finished products. Pharm. Ind. 56, 478-483 (1994). TLC of albendazole and mebendazole on silica with hexane - ethyl acetate - acetic acid 7:2:1. Detection under UV 254 nm, by exposing to iodine vapor. and by spraying with Dragendorff / Ce(SO4)2.

      Classification: 32a
      75 119
      Rapid screening of pharmaceuticals by thin-layer chromatography
      A.S. KENYON, P.E. FLINN, T.P. LAYLOFF, (U.S. Food and Drug Administration, Center for Drug Evaluation and Research, Div. of Drug Analysis, 1114 Market St., Room 1002, St. Louis, MO 63101-2045, USA)

      J. AOAC Int. 78, 41-49 (1995). TLC on silica: of acetaminophen with ethyl acetate - methanol - NH3 85:10:5; of amoxicillin, ampicillin, benzylpenicillin, cloxicillin with acetone - water - toluene - acetic acid 26:4:4:1; of chloramphenicol with chloroform - methanol 9:1; of chloroquine phosphate with ethanol - water - NH3 85:11:4; of estradiol cypionate with chloroform - toluene - ethyl acetate - methanol 45:36:6:1; of mebendazole with chloroform - methanol - formic acid 90:5:5; of praziquantel with chloroform - acetone 1:1; of quinine sulfate with ethanol - NH3 - water 85:4:1; of sulfamethazine, sulfamethoxazole with chloroform - acetone - methanol - NH3 - water 80:80:40:3:2; of theobromine, theophylline with chloroform - acetone 1:1; of trifluoperazine with acetone - NH3 24:1. Detection by immersion into a solution of iodine and acidified potassium iodide; quantification by densitometry at 254 nm.

      Classification: 28a, 32a
      77 111
      Two-dimensional, two-phase TLC determination of parabens in pharmaceutical formulations
      N. DIMOV, K. FILCHEVA, (NIHFI, 3 Kl. Okhridsky St, 1756 Sofia, Bulgaria)

      J. Planar Chromatogr. 9, 197-198 (1996). TLC of sorbic acid, p-hydroxybenzoic acid, parabens, carbamazepine, methylparaben, propylparaben on silica with e.g. toluene - isopropanol - diethylamine 10:10:1 in the first direction and after impregnation of the plate with paraffin in n-hexane resp. with methanol - water - acetic acid 350:150:1, saturated with liquid paraffin, in the second direction. Detection under UV. The proposed approach has the advantage of enabling determination of p-hydroxybenzoic acid in the presence of other acidic compounds.

      Classification: 32a
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