Abstract No. F-267, 61st IPC (2009). HPTLC of camylofin dihydrochloride on silica gel with chloroform - ethyl acetate - methanol - 25 % ammonia 50:30:20:1. Quantitative determination by absorbance measurement at 215 nm. Linearity was in the range of 1.5-7.5 µg/band. The proposed method is suitable for routine quality control of bulk drug and tablets.

Indian Drugs 46(1), 78-81 (2009). HPTLC of atenolol and losartan potassium in tablets on silica gel with toluene - methanol - triethylamine 12:8:1 with chamber saturation for 45 min. Quantitative determination by absorbance measurement at 230 nm. The hRf value of atenolol was 45 and of losartan potassium 67. The method was linear in the range of 1000-4000 ng/spot for both compounds. The recovery was 98.8-98.9 %.

60th Indian Pharmaceutical Congress PA-229 (2008). HPTLC of voriconazole on silica gel with toluene - methanol - glacial acetic acid 78:20:1. Quantitative determination by absorbance measurement at 254 nm. The method was linear in the range of 50-400 ng/spot, recovery was 99.9-100.7 %. The method was suitable for routine quality control of the dosage form.

Indian Drugs 47(2), 71-74 (2010). HPTLC of irbesartan and hydrochlorothiazide on silica gel with acetone - chloroform - ethyl acetate - methanol 6:6:6:1. The plates were preconditioned for 10 min in a saturated chamber prior to development. The hRf value of irbesartan was 27 and of hydrochlorothiazide 37. The linearity was 1500-9000 ng/band and 125-750 ng/band for irbesartan and hydrochlorothiazide respectively. The average recovery for both drugs was 99.4-99.5 %.

International Journal of ChemTech Research 2(2), 1042-1046 (2010) HPTLC on silica gel with dichloromethane - methanol 9:1 in a twin-trough chamber saturated for 30 min. The hRf value was 70. Densitometric evaluation in absorbance mode at 254 nm. The method was linear in the range of 400-2000 ng/band. The average recovery was 101.2 %.

J. Planar Chromatogr. 24, 419-422 (2011). TLC of levamisole on silica gel with methanol - toluene - chloroform 14:35:50 in a twin-trough chamber saturated for 15 min at 25 °C. The hRf value was 30. Quantitative determination by densitometry in absorbance mode at 223 nm. Linearity was between 50 and 2000 ng/zone. The recovery was 88.4-102.6 %. The %RSD for intra-day and inter-day precision was 1.9 % and 2.0 %, respectively. The LOD and LOQ was 2 and 7 ng/zone, respectively.

J. AOAC Int. 94, 1094-1099 (2011). TLC of caffeine and paracetamol in capsules and tablets on silica gel with n-hexane - ethyl acetate - ethanol 25:15:4. Detection at 254 nm. Quantitative determination by densitometry at 254 and 270 nm. The hRf value of caffeine and paracetamol was 48 and 73, respectively. Linearity was between 0.2-1.9 for caffeine and 0.03-1.5 µg/L for paracetamol. The detection limit of caffeine was 25 ng/L and of paracetamol 32 ng/L. The precision was 1.9 % (n=6). Recovery (by standard addition) was 98-99.5 % for both compounds.

J. Planar Chromatogr. 24, 348-351 (2011). Study of the lipophilicity and specific hydrophobic surface area of fourteen 1,3-benzoxazol-2(3H)-ones substituted in the benzene ring (fluoro-, chloro-, bromo-, dibromo-, amino-, and nitro-derivatives). TLC on RP-18 with methanol - water, methanol - aminoacetic acid buffer pH 2.7, and methanol - aminoacetic acid buffer pH 11.6. The concentration of methanol in the mobile phase ranged from 30-90 % in all cases. Detection under UV 254 nm. The linear correlation between the volume fraction of methanol and values over a limited range were established with good correlation coefficients (r > 0.98). The obtained results were compared with calculated partition coefficients.