Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
  • Browse and search by CBS classification: Select one of the 38 CBS classification categories where you want to search by a keyword
  • Keyword register: select an initial character and browse associated keywords
  • Search by CBS edition: Select a CBS edition and find all related publications

Registered users can create a tailor made PDF of selected articles throughout CCBS search – simply use the cart icon on the right hand of each abstract to create your individual selection of abstracts. You can export your saved items to PDF by clicking the download icon.

Page
      105 085
      Use of photocatalytic reactions to visualize drugs in TLC
      A. MAKOWSKI*, E. ADAMEK, W. BARAN (*Medical University of Silesia, Faculty of Pharmacy, 4 Jagiellonska Street, 41-200 Sosnowiec, Poland; makowski.andrzej@gmail.com)

      J. Planar Chromatogr. 23, 84-86 (2010). TLC of 18 drugs (6 antibiotics [benzyl-penicillin procaine, benzyl-penicillin potassium, penicillic acid, tetracycline hydrochloride, oxytetracyline hydrochloride, chlortetracycline hydrochloride], 2 analgesics [aminophenazone, salicylamide], 2 anaesthetics [phenazone, procaine hydrochloride], and one each of anti-rheumatic [penicillamine], anti-inflammatory [metamizole sodium], antitussive [codeine phosphate], broncholytic [aminophylline], spasmolytic [papaverine hydrochloride], hypnotic [phenobarbital], sympathomimetic [ephedrine hydrochloride] and vitamin [ascorbic acid] drugs) on silica gel with butanol - anhydrous acetic acid - water 3:1:1. Detection by spraying with 10 mL each of a solution of (A) 0.25 g titanum dioxide in 0.1 mol/L potassium permanganate, (B) 0.25 g titanium dioxide in 1.0 mol/L potassium iodide, (C) 0.25 g titanium dioxide in 1.0 mol/L potassium bromide, which was the best (most sensitive) one, and (D) 0.25 g titanium dioxide in 1.0 mol/L potassium chloride. After spraying with reagents C and D, plates were illuminated for 10 min, sprayed with 0.1 mol/L silver nitrate solution and illuminated again for 3 min. In all experiments the TLC plates were illuminated by use of UV lamps with the radiation at 366 nm. LODs for most of the drugs studied were in the range 0.2-0.5 µg/spot.

      Classification: 32a
      105 121
      A validated thin-layer chromatographic method for analysis of bupropion hydrochloride in a pharmaceutical dosage form
      D. YENICELI, D. DOGRUKOL-AK* (*Anadolu University, Faculty of Pharmacy, Department of Analytical Chemistry, 26470 Eskisehir, Turkey; dak@anadolu.edu.tr)

      J. Planar Chromatogr. 23, 212-218 (2010). TLC of bupropion on silica gel with ethanol - chloroform - glacial acetic acid 30:10:1. The hRf value was 56. Quantitative determination by densitometry at 254 nm. Linearity was in the range 200-1000 ng/band (via peak area). The limits of detection and quantitation were 11 and 35 ng per band, respectively. The intra-day repeatability of the method was around 1-2 % RSD. Recovery was between 102.1 and 104.6 % and between 97.2 and 102.2 % for quality-control standards and for bupropion hydrochloride, respectively.

      Classification: 32a
      107 113
      A new simple method for determination of partition coefficient by normal phase TLC
      P. CHOTHE*, S. DESHMUKH, A. KAKADE, I. RAUT (*Dept. fo Pharmaceutical Chemistry, Rajarambapu College of Pharmacy, Kasegaon 415404, Tal. Walwa Dist. Sangli, (MS), India)

      62nd Indian Pharmaceutical Congress Abstract No. F-382 (2010). The partition coefficient (logP) of a drug in benzene – water is an important parameter to determine the absorbance of the drug in body, thus influencing its therapeutic response. A NP-TLC method for the determination and calculation of log P values is proposed. By this method differential values like Rfb/w, LogRfb/logRfw were calculated, which were very close to values reported in literature. LogP values of different drugs were 0.46 for paracetamol, 0.22 for atenolol, 5.11 for telmisertan, and 0.9 for nimesulide.

      Classification: 32a
      108 133
      Normal-phase TLC analysis of UV filter avobenzone and octocrylene in sunscreen preparations
      Anna SOBANSKA*, E. BRZEZINSKA (*Department of Analytical Chemistry, Medical University of Lodz, UL. Muszynskiego 1, 90-151 Lodz, Poland; a.sob@poczta.onet.pl)

      J. Planar Chromatogr. 24, 154-159 (2011). TLC of avobenzone (methoxydibenzoylmethane), octocrylene, Uvinul T 150 (ethyl hexyl triazone, ET), and ethylparaben on silica gel with cyclohexane - diethyl ether 1:1 (method A), or with cyclohexane - piperidine 15:1 (method B), in a chamber lined with filter paper and saturated for 20 min. Quantitative determination by densitometry at 380 nm for avobenzene and at 300 nm for octocrylene. LOD and LOQ were 170 and 510 ng/zone for avobenzone (method A) and 180 and 537 ng/zone for octocrylene (method B), respectively. The linearity range was 200-1800 ng/zone for avobenzone and octocrylene.

      Classification: 32a
      109 107
      Application of stability indicating high-performance thin-layer chromatographic method for quantitation of pramipexole in pharmaceutical dosage form
      S. PAWAR, S. DHANESHWAR* (*Department of Pharmaceutical Chemistry, Bharati Vidyapeeth University, Poona College of Pharmacy, Pune, Maharashtra, India 411038, sunil.dhaneshwar@gmail.com)

      J. Liq. Chromatogr. Relat. Technol. 34, 1664-1675 (2011). HPTLC of pramipexole in pharmaceutical formulations on silica gel with ethyl acetate - toluene - methanol 16:3:1 + 1 drop ammonia. Quantitative determination by absorbance measurement at 263 nm. The hRf value of pramipexole was 32. Precision was below 2 %. Linearity was 200-2000 ng/zone. LOD and LOQ were found to be 30 and 200 ng/zone. The intermediate/inter-day/intra-day precision (n = 6) was 0.4 %. Recovery (by standard addition) was in the range of 98.5-99.1 %.

      Classification: 32a
      110 107
      Simultaneous HPTLC analysis of atorvastatin calcium, ezetimibe, and fenofibrate in tablet
      C. MACWANA*, A. PATEL, V. PARMAR, S. PATEL (*Institute of Pharmaceutical Education and Research, Gh-6, Sec 23, Gandhinagar, India, chhayamacwana111@gmail.com)

      J. Liq. Chromatogr. Relat. Technol. 35, 524-532 (2012). HPTLC of atorvastatin calcium (1), ezetimibe (2), and fenofibrate (3) in tablet on silica gel with toluene – chloroform – methanol 23:15:7 + 1 drop glacial acetic acid. Quantitative determination by absorbance measurement at 253 nm. The hRf values of active agents (1) - (3) were 20, 33 and 80, respectively. Linearity was 200-800 ng/zone for (1) and (2) and 4-16 µg/zone for (3). The intermediate/inter-day/intra-day precision was below 1.1 % for (1), 1.3 % for (2) and 1.5 % for (3) (n=6). The limits of detection and quantification were 19 and 59 ng/zone for (1), 23 and 68 ng/zone for (2), and 1449 and 4390 ng/zone for (3), respectively. Recovery (by standard addition) was between 99.1 and 99.8 % for compounds (1) to (3).

      Classification: 32a
      111 049
      Stability-indicating HPTLC method of carteolol in bulk drug and in pharmaceutical dosage forms
      AMEEDUZAAFAR, A. ALI, A. ALI* (Department of Pharmaceutics, Faculty of Pharmacy, Jamia Hamdard, New Delhi-62, India, alipharm@gmail.com*)

      J. Planar Chromatogr. 26, 86-92 (2013). HPTLC of carteolol on silica gel with chloroform - methanol 5:1. Quantitative determination by absorbance measurement at 254 nm. The hRf of carteolol was 31. Linearity was in the range of 200-1200 ng/zone. LOD and LOQ were 34 ng/zone and 104 ng/zone, respectively. Intermediate precision was below 2 %. The method could effectively separate the drug from its degradation products.

      Classification: 32a
      111 126
      Development and validation of an HPTLC method for simultaneous estimation of thiocolchicoside and aceclofenac in combined dosage form
      P. SYAL, M. SAHOO, R. RAUT, A. HABLE, A. BATTEWAR, V. CHOUDHARI*, B. KUCHEKAR (*Maharashtra Institute of Pharmacy, MIT Campus, Paud Road, Kothrud, Pune 411038, MS, India, viraj1404@rediffmail.com)

      J. Planar Chromatogr. 25, 133-137 (2012). HPTLC of thiocolchicoside (1) and aceclofenac (2) in combined dosage form on silica gel with methanol - chloroform - water 48:1:1. Quantitative determination by absorbance measurement at 254 nm. The hRf values of (1) and (2) were found to be 70 and 83, respectively. Linearity was in the range of 30-180 ng/band for (1) and 750-4500 ng/band for (2). Recovery was in the range of 98.7-101.2 % for both.

      Classification: 32a
Page