Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
  • Browse and search by CBS classification: Select one of the 38 CBS classification categories where you want to search by a keyword
  • Keyword register: select an initial character and browse associated keywords
  • Search by CBS edition: Select a CBS edition and find all related publications

Registered users can create a tailor made PDF of selected articles throughout CCBS search – simply use the cart icon on the right hand of each abstract to create your individual selection of abstracts. You can export your saved items to PDF by clicking the download icon.

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      76 185
      Identification of efonidipine hydrochloride metabolites in rats
      H. Nakabeppu, A. Nakajima, Y Kamikawaji, Y Shinozaki, (Shiraoka Res. Station of Biological Science, Nissan Chemical Industries, Ltd., Saitama, Japan)

      Arzneim.-Forsch./Drug Res. 45, 766-770 (1995). TLC of efonidipine hydrochloride (2-benzyl(phenyl)amino)ethyl 1,4-dihydro-2,6-dimethyl-5-(5,5-dimethyl-2-oxo-1,3,2-dioxaphosphorinan-2-yl)-4-(3-nitrophenyl)-3-pyridinecarboxylate hydrochloride ethanol) and metabolites on silica with chloroform - methanol - diethylamine 18:1:1 or chloroform - methanol 1:1. Detection under UV 254 nm.

      Classification: 32b
      82 116
      Isolation and identification of metabolites of 3H- and 14C-deramciclane by OPLC-digital autoradiography on-line sample collection and mass spectrometry
      I. KLEBOVICH*, E. MINCSOVICS, J. SZUNYOG, K. LUDANYI, T. KARANCSI, K. /JSZASZY, B.D. KISS, K. VEKEY, (Dept. of Pharm., EGIS Pharmaceuticals Co. Ltd., H-1106 Budapest, Keresztúri út 30 - 38, Hungary)

      J. Planar Chromatogr. 11, 394-399 (1998). A new simple and powerful technique, on-line sample collection after high-resolution step-wise gradient OPLC separation combined with digital autoradiography (DAR) has been used for isolation of plasma and urine metabolites of 3H- or 14C-radiolabeled deramciclane (a new anxiolytic compound). This highly efficient separation can be followed by different MS techniques (FAB-MS, FAB-MS-MS, HPLC-MS, and HPLC-MS-MS) for determination of the structures of minor and major metabolites in different biological matrices. The combination of these methods resulted in a simple, sensitive, and efficient technique for metabolite research. OPLC on HPTLC silica gel, prewashed with methanol - water 4:1 with A) chloroform - acetonitrile 3:2 and B) n-butanol - acetic acid - water 4:1:1 for the gradient. Detection by digital autoradiography.

      Keywords:
      Classification: 32b
      100 166
      HPTLC method for the determination of cinnamaldehyde in Cinnamomum zeylenicum bark powder
      R.M. SINGH, S.C. MATHUR*, P. SINGH, O. PRAKASH, D.K. SHARMA, P.K. SAINI, G.N. SINGH (*Central Indian Pharmacopoeia Laboratory, Govt. Of India, Ministery of Health and Family Walfare, Ghaziabad, Uttar Pradesh, India)

      59th Indian Pharmaceutical congress F-225, 443, (2007). HPTLC cinnamaldehyde in the bark powder of Cinnamomum zeylenicum on silica gel with toluene - ethyl acetate - formic acid 190:10:1. Densitometric evaluation at 295 nm for quantification. The method was linear within the range of 31 and 157 ng/zone. The identity of the compound was confirmed by over overlaying the UV spectra of sample and standard. Cinnamomum bark was found to contain 0.25 % of cinnamaldehyde. Limit of detection and quantification was 3000 and 9900 ng/mL, respectively.

      Classification: 32c
      103 085
      Stability-indicating TLC method for the determination of dutasteride in pharmaceutical dosage forms
      V.P. CHOUDHARI*, Anna P. NIKALJE (*Maharashtra Institute of Pharmacy, MIT Campus, Paud Road, Kothrud, Pune, 411038, Maharashtra, India)

      Chromatographia 70 (1-2), 309-313 (2009). TLC on silica gel with acetonitrile - methanol - dichloromethane 2:1:2. The hRf value of dutasteride was 64. Separation of dutasteride from its degradation products (produced by acid and alkali hydrolysis, oxidation, photo degradation, dry and wet heat treatment) was good. Quantitative determination by absorbance measurement at 244 nm. Linearity was in the range of 100 - 600 ng/band and the correlation coefficient was 0.9943 (via peak area) The limit of detection and quantitation was 7 and 23 ng/band.

      Classification: 32c
      104 184
      (Identification of Shenlingbaizhu pills by thin-layer chromatography) (Chinese)
      T. QU (Qu Tingli), Y. DENG (Deng Yaning), L. HAU (Hau Lihong), ZH. ZHAO (Zhao Zhengbao)* (*Pharm. Coll., Shanxi Univ. Med., Taiyuan Shanxi 030001, China)

      J. Chinese Trad. Patent Med. 30 (12), Supl. 4-6 (2008). TLC of the TCM drug extracts on silica gel with 1) dichloromethane - ethyl acetate - methanol - water 15:40:22:10; 2) petroleum ether (60-90 °C) - diethyl ether 3:2; 3) petroleum ether (60-90 °C) - ethyl acetate 25:2; 4) n-butanol - acetic acid - water 4:1:2; 5) chloroform - diethyl ether 1:1. Detection 1) by spraying with 10 % sulfuric acid in ethanol followed by heating at 105 °C until coloration; 2) under UV 365 nm; 3) under UV 254 nm.

      Classification: 32c
      106 175
      Quantitative determination of oxybutynin hydrochloride by spectrophotometry, chemometry and HPTLC in presence of its degradation product and additives in different pharmaceutical dosage forms
      N.E. WAGIEH*, Maha HEGAZY, M. ABDELKAWY, E.A. ABDELALEEM (*Analytical Chemistry Department, Faculty of Pharmacy, Beni-Suef University, Egypt)

      Talanta, 80 (5), 2007-2015 (2010). Presentation of a method for determination of oxybutynin hydrochloride (OX) in presence of its degradation product and additives in its pharmaceutical formulations. UV spectrophotometry using the first derivative of ratio spectra and measurment at 216 nm. Chemometric analysis using principal component regression and partial least-squares. HPTLC of OX and its degradation products methylparaben and propylparaben on silica gel with chloroform - methanol - ammonia - triethylamine 500:15:2.5:1. Quantitative determination by densitometry at 220 nm. Comparison of the results obtained with all three methods showed no significant differences.

      Classification: 32c
      107 152
      (Determination of gentamicin in fermentation broth by thin-layer chromatography) (Chinese)
      X. YANG* (Yang Xuming), J. ZHANG (Zhang Jiali), J. LI (Li Jianghua) , J. FANG (Fang Jun) (*School of Med. & Pharm., Jiangnan Univ., Wuxi, Jiangsu 214122, China)

      J. of Food Sci. & Biotechnol. 27(5), 129-133 (2008). TLC of gentamicin on silica gel with the lower phase of chloroform – methanol – 25 % ammonia 5:4:3 and after chamber saturation with the upper phase of the developing solvent. Detection by exposure to iodine vapor. Identification by comparison of the hRf values with the standards of the main components of gentamicin (Cl, C1 and C2). The results were compared with results obtained by HPLC and good agreement between both methods was found.

      Classification: 32c
      115 067
      Quantitative determination of paroxetine in human serum by high-performance thin-layer chromatography
      S. MENNICKENT*, Cristina CIFUENTES, M. VEGA, Gisela RIOS, Marta DE DIEGO (*Department of Pharmacy, Faculty of Pharmacy, University of Concepcion, P.O. Box 237, Concepcion, Chile, smennick@udec.cl)

      J. Planar Chromatogr. 28, 229-233 (2015). HPTLC of paroxetine in human serum on silica gel with toluene - acetone - ethanol - ammonia 25 % in water 9:5:2:1. Quantitative determination by absorbance measurement at 294 nm. Linearity was between 0.01 and 0.14 ng/µL. The intra-day precisions were between 0.9 % and 2.2 % (n=5) and the inter-day precisions were between 1.0 % and 3.9 % (n=9). The LOD and LOQ was 0.3 and 0.6 ng/zone, respectively. Recoveries were between 91.5 % and 96.5 %.

      Classification: 32c
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