International Journal of Pharma and Bio Sciences 1(4), 339-345 (2010). TLC on silica gel (plates pre-washed with methanol) with chloroform - toluene - methanol - glacial acetic acid 50:20:30:1. The hRf value of s-amlodipine was 33 and of nebivolol 48. Densitometric evaluation at 271 nm. The linearity range was 500-2500 ng/zone for nebivolol and 250-1250 ng/zone for s-amlodipine. The method was suitable for routine analysis of the formulation.

Acta Chromatographica 22 (1), 91-97 (2010), DOI:10.1556/AChrom.22.2010.1.7. TLC on silica gel with chloroform – methanol – toluene 4:3:3. The hRf value was 77 and 29 for cefuroxime axetil and potassium clavulanate, respectively. Quantification by densitometry at 225 nm. The linearity was in the range of 0.5–2.5 and 2–10 µg/band, respectively. Application of the method for analysis of the drugs in a pharmaceutical formulation with a recovery of 100.1 % for cefuroxime axetil and 99.9 % for potassium clavulanate.

J. Chinese Modern Med. & Pharm. 20 (31), 54-56 (2013). Paracetamol and chlorphenamine maleate granule are an anti cold medicine effective for cold induced nasal congestion, headache, sore throat, fever, etc. Artificial bezoar is one of the main ingredients and bilirubin is the key effective component in the medicine. For quality control, TLC of the extracts and bilirubin on silica gel with isooctane – ethyl acetate – glacial acetic acid 11:5:3, detection under white light. Quantitative determination of bilirubin by UV spectrophotometry. Demonstration by applying to real life samples from three pharmaceutical factories indicated that the method was suited for the quality control of the medicine.

J. Chromatogr. Sci. 54 (5), 842-846 (2016). Development of a new chromatographic method for direct enantioresolution of (RS)-baclofen by ligand-exchange TLC, adopting two different approaches: (A) on plates prepared by mixing the ligand exchange reagents (LER) with silica gel slurry, development with different achiral solvents or solvents without chiral additive; (B) on silica gel without chiral selector and the LER consisting of Cu(II)–L-amino acid complex as chiral mobile phase additive. Preparation of LERs by using Cu(II) acetate and four L-amino acids (L-tryptophan, L-histidine, L-proline and L-phenylalanine). Detection by exposure to iodine vapor. Study of the effect of temperature and the mole ratio of Cu(II)-to-amino acid on enantioresolution. L-tryptophan proved to be a good ligand using a common mobile phase in each case.

Chromatographia 18, 253-259 (1984). HPTLC of antiarrhythmic drugs on silica with benzene - ethyl acetate - methanol - triethylamine 7:6:1:1 and of chloramphenicol on silica with heptane - chloroform - methanol 6:12:3. Densitometry by absorbance at 265 nm or by fluorescence for the former and by absorbance at 280 nm for the latter. Method for monitoring of therapeutic drugs in blood serum. Comparison with EMIT and HPLC.

J. Chromatogr. 350, 151-168 (1985). TLC on silica with four developing systems: 1) ethyl acetate - methanol - 30% NH3 85:10:5, 2) cyclohexane. - toluene - diethylamine 65:25:10, 3) ethyl acetate - chloroform 5:5, 4) acetone with the plate dipped in KOH solution. Detection by spraying with Dragendorff reagent and acidified iodoplatinate solution. A two-component model accounting for 73% of the total variance. Results of great practical importance in analytical toxicology.

(Detection of prajmaliumbitartrate (neo-gilurytmal) in urine by thin-layer chromatography). Pharmazie 42, 550-551 (1987). TLC of the antiarrhythmic prajmalin on silica with methanol - acetic acid - HCl 10:85:5, chloroform - ethanol - acetic acid 15:15:10 and toluene - ethanol - acetone - diethyl amine 30:20:20:1. Detection with Dragendorff’s reagent modified by Kaiser and Jori (addition of 1 g cersulfat and 1 mol/L, conc. nitric acid).

(Water determination in Erythromycin by Karl Fischer method). Dtsch. Apoth. Ztg. 127, 2034-2036 (1987). TLC of Erythromycin on silica with ethyl acetate - isopropanol - methanol 80:30:20 after saturation with 15% ammonium acetate solution (pH 9.6). Detection by spraying with anisaldehyde - sulfuric acid and heating at 110°C.