Cumulative CAMAG Bibliography Service CCBS
Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.
The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:
- Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
- Browse and search by CBS classification: Select one of the 38 CBS classification categories where you want to search by a keyword
- Keyword register: select an initial character and browse associated keywords
- Search by CBS edition: Select a CBS edition and find all related publications
Registered users can create a tailor made PDF of selected articles throughout CCBS search – simply use the cart icon on the right hand of each abstract to create your individual selection of abstracts. You can export your saved items to PDF by clicking the download icon.
hydrochlorothiazide, enalapril, and atorvastatin in a polypill-based quaternary mixture by TLC
J. AOAC Int. 3, 708-713 (2018). HPTLC of acetylsalicylic acid (1), hydrochlorothiazide (2), enalapril (3), and atorvastatin (4) in a formulation on silica gel with n-hexane – ethyl acetate – methanol – water – acetic acid 42:40:15:2:1. Quantitative determination by absorbance measurement at 210 nm for (3) and 265 nm for (1), (2) and (4). The hRf values for (1) to (4) were 68, 44, 31 and 54, respectively. Linearity was in the range of 0.600-6.000 μg/zone for (1), 0.058-1.102 μg/zone for (2), 0.505-6.560 μg/zone for (3) and 0.100-1.000 μg/zone for (4). The intermediate precision was below 3 % (n=5). The LOD and LOQ were 0.311 and 0.942 μg/zone for (1), 0.043 and 0.130 μg/zone for (2), 0.331 and 1.003 μg/zone for (3) and 0.044 and 0.135 μg/zone for (4). (Note by the editor: Calibration should start at LOQ, not below.) Recovery was between 97.0 and 101.3 % for (1) to (4).
method for the simultaneous determination of zofenopril calcium and hydrochlorothiazide in the presence of the hydrochlorothiazide impurities
J. AOAC Int. 101, 1031-1041 (2018). HPTLC of zofenopril calcium (1) and hydrochlorothiazide (2) in the presence of the hydrochlorothiazide impurities chlorothiazide (3) and salamide (4) on silica gel with ethyl acetate – glacial_x000D_ acetic acid – triethylamine 100:1:1. Quantitative determination by absorbance measurement at 270 nm. The hRF values for (1) to (4) were 34, 44, 25 and 64, respectively. Linearity ranged between 0.5-10.0 μg/zone for (1), 0.2-4.0 μg/zone for (2), 0.05-1.4 μg/zone for (3) and 0.05-1.0 μg/zone for (4). LOD and LOQ were 20 and 50 ng/zone for (3) and (4). The intermediate precision was <2 % (n=3). Average recovery was 100.0 % for (1), 99.6 % for (2), 99.5 % for (3) and 99.2 % for (4).
(Hungarian) (Data on the thermo and light stability of the receptorblocking agent CH-103.) CH-103 = (4-cyclohexylamino-1-(1-naphtyloxy)-2-butanol-hydrogenmaleate) is a new Hungarian pharmacon. TLC on silica with ethyl acetate - methanol -25 % NH3 8:1:1 Detection by UV and with iodine. Spectrophotometry after elution. Main decomposition products identified: 1-naphtol, 4-cyclohexylamine-1,2-butandiol, 1-cyclohexenyl-3-pyrrolidinol.
(Assay of nithiocyamine in suppositories by TLC densitometry.) TLC of nithiocyamine on silica with benzene - chloroform 5:5.
(Simple qualitative determination of pharmaceutical active ingredients in urine.) Swiss Pharma 8, 6-17 (1986) Qualitative identification of 19 drugs by 1. isolation from the matrix, 2. separation from accompanying substances using TLC and 3. detection (i. a. via fluorescence and fluorescence quenching, chemical reaction. TLC on silica with toluene - isopropanol - NH3 3:6:1. Detection with trichlorobenzoquinone imine, Dragendorff reagent, diphenylcarbazonel mercury II, UV 366 nm.
Quantitative and identification methods. J.A.O.A.C. 71, 220-222 (1988). TLC of dexamethasone on silica with chloroform - diethyl amine 2:1 or chloroform - acetone - glacial acetic acid 80:40:1. Detection under UV 254 nm.
J. of Medicinal Chemistry 31, 1021-1026 (1988). TLC of 7H-pyrido(4,3- c)carbazole on silica with isobutanol - pyridine - acetone - water 5:2:1:2, 2-propanol- ammonium hydroxide 7:3, isobutanol-ammonium hydroxide 17:5 and carbon tetrachloride - methanol 9:1.
J. Chromatogr. 409, 426-432 (1987). TLC of ellipticine, 9-hydroxy ellipticine and 9-methoxy ellipticine on silica with ethyl acetate - water - 1-octanol 17:2:2. Detection by fluorodensitometry at 290 nm excitation, 400 and 440 nm emission. Detection limits = 40, 80, 300 f mol for the three compounds, respectively.