Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
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Registered users can create a tailor made PDF of selected articles throughout CCBS search – simply use the cart icon on the right hand of each abstract to create your individual selection of abstracts. The saved items can be printed to PDF using the print function of your web browser.

      Diterpene lipo-alkaloids with selective activities on cardiac K+ channels
      T. KISS, B. BORCSA, P. ORVOS, L. TÁLOSI, J. HOHMANN, D. CSUPOR* (*Department of Pharmacognosy, Faculty of Pharmacy, University of Szeged, Szeged, Hungary; csupor.dezso@pharmacognosy.hu)

      Planta Med. 83(17), 1321-1328 (2017). Benzoyl-aconine esters (lipo-alkaloids) produced by transesterification of aconitine (isolated from Aconitum sp.) with long-chain fatty acids were purified by a multistep chromatographic method, including cyclodextrane gel filtration chromatography, centrifugal planar chromatography on aluminium oxide layer using cyclohexane – chloroform – methanol 70:30:1 followed by 70:30:3 and/or preparative thin-layer chromatography on aluminium oxide layer with toluene – acetone – ethanol – concentrated ammonia 70:40:10:3.

      Classification: 32e, 22, 11a, 4d, 4e
      Microscopic and phytochemical comparison of the three Leonurus species L. cardiaca, L. japonicus, and L. sibiricus
      Anna PITSCHMANN, C. WASCHULIN, C. SYKORA, S. PUREVSUREN, S. GLASL* (*Department of Pharmacognosy, University of Vienna, Vienna, Austria; sabine.glasl@univie.ac.at)

      Planta Med. 83(14/15), 1233-1241 (2017). HPTLC of standards and methanolic extracts of L. cardiaca, L. japonicus and L. sibiricus (Lamiaceae) acidified with formic acid on silica gel with ethyl acetate – acetic acid – formic acid – water 100:11:11:26, in an automatic development chamber with 48 % humidity (20 min presaturation). Detection under white and UV light, before and after immersion in 1) anisaldehyde – sulphuric acid (followed by heating) for the detection of iridoids; 2) natural product reagent A for phenylpropanoids; 3) modified Dragendorff reagent (bismuth oxynitrate 0.17 %, sulfuric acid 3.5 %, glacial acetic acid 2 %, potassium iodide 4 %) for alkaloids. Ajugoside (hRF 29) and verbascoside (hRF 53) were found in L. cardiaca and L. sibiricus, but absent in L. japonicus. The opposite was true for leonurine (hRF 52), whereas stachydrine (hRF 14) was found in the three species. This method allows to distinguish L. japonicus from the other species, which have to be distinguished from each other through morphology.

      Classification: 32e, 22, 8
      A harmonized HPTLC method for identification of various caffeine containing herbal drugs, extracts, and products, and quantitative estimation of their caffeine content
      Tien DO*, I. SANTI, E. REICH (*CAMAG Laboratory, Sonnenmattstrasse 41, 4132 Muttenz, Switzerland, tien.do@camag.com)

      J. Liq. Chromatogr. Relat. Technol. 42, 274-281 (2019). HPTLC of caffeine in caffeine-containing botanicals and caffeinated products on silica gel with toluene - acetone - formic acid 9:9:2. Detection by dipping into NP reagent (1 g of diphenylborinic acid aminoethylester in 200 mL of ethyl acetate), followed by derivatization with anisaldehyde reagent, then heating at 100 ºC for 3 min. Quantitative determination by absorbance measurement at 273 nm. The hRF value of caffeine was 70. Linearity was between 30 and 120 ng/zone. The intra-day and inter-day precision was below 5 % (n=3). The LOD and LOQ were 10 and 30 ng/zone, respectively. Recovery rate was between 101 and 118 %.

      Classification: 22
      Development and validation of a High-Performance Thin-Layer Chromatography based method for the quantification of Trigonelline in fenugreek (Trigonella foenum-graecum) seeds
      O. LAILA, I. MURTAZA*, M. ABDIN, S. AHMAD, M. KHAN (*Biochemistry and Molecular Biotechnology Laboratory, Division of Basic Sciences and Humanities, SKUAST-K-190025, India, imz_murtaza@hotmail.com)

      J. Planar Chromatogr. 32, 95-102 (2019). HPTLC of trigonelline in the seeds of Fenugreek
      (Trigonella foenum-graecum) on silica gel with n-propanol - methanol - water - ammonia 40:6:15:1. Quantitative determination by absorbance measurement at 270 nm. The hRF value of trigonelline was 40. Linearity was between 100 and 1200 ng/zone. The intermediate precision was 0.7 % (n=6). The LOD and LOQ were 14 and 52 ng/zone, respectively. Recovery rate was 100.1 %.

      Classification: 22
      A comparative estimation of the morphine content of the Ayurvedic formulation ‘Kamini Vidrawan Ras’ using validated High-Performance Thin-Layer Chromatography and High-Performance Liquid Chromatography techniques
      A. SHARMA, C. DHAL, R. SRIVASTAVA* (*Department of Applied Chemistry, Delhi Technological University, Delhi 110042, India, richa_srivastava@dce.ac.in)

      J. Planar Chromatogr. 32, 47-50 (2019). HPTLC of morphine hydrochloride in the Ayurvedic formulation "Kamini Vidrawan Ras" on silica gel with ethyl acetate - methanol - ammonia solution 17:2:1. Quantitative determination by absorbance measurement at 280 nm. The hRF value of morphine was 36. Linearity was between 0.4 and 1.2 µg/mL. The intermediate precision was below 1 % (n=6). The LOD and LOQ for morphine were 0.5 and 1.5 µg/mL, respectively. Recovery rate was 100.0 %. Results were comparable to a validated HPLC method.

      Classification: 22
      100 046
      HPTLC quantitation of camptothecin in Nothapodytes foetida (Wight) Sleumer stem powder
      V. DIGHE, R.T. SANE, G. PAREKH*, V. GOKARN, O. DHOTRE (*Department of Chemistry, Ramnarain Ruia College, Matunga (East), Mumbai-400 019, India; gaurangparekh80@yahoo.co.in)

      J. Planar Chromatogr. 20, 131-133 (2007). HPTLC of camptothecin (4-ethyl-4-hydroxy-1H-pyrano[3’,4’6,7]indolizino[1,2b]quinoline-3,14(4H,12H)dione) on silica gel with toluene - acetonitrile - glacial acetic acid 65351. Detection and quantitation were performed by densitometric scanning in fluorescence mode at 370 nm.

      Classification: 22
      104 005
      Determination of the lipophilicity of selected isoquinoline alkaloids by RP-TLC
      M. WAKSMUNDZKA-HAJNOS, D. MATOSIUK, A. PETRUCZYNIK, U. KIJKOWSKA-MURAK* (*Medical University of Lublin Department of Inorganic Chemistry 20-081 Lublin Poland)

      Acta Chromatographica 24 (4), 563-573 (2008). TLC of nine alkaloids on RP-18 with mixtures of aqueous acetone or aqueous dioxane with various mobile phase additives (ammonia, diethylamine, or tetrabutylammonium chloride) in order to suppress ionization of the alkaloids and/or reduce ionic interactions with surface silanol groups. Ion-pair TLC on RP-18 with aqueous acetone mixtures and various mobile phase additives (pentane sulfonic acid, octane sulfonic acid, or di-(2-ethylhexyl)orthophosphoric acid). Investigation of relationships between RM values and modifier concentration using a linear semilogarithmic equation for experimental data to calculate lipophilicity values RMW (RM for pure water), the slope, and the intercept with the x -axis. Comparison with retention data of standards with known lipophilicity (log P).

      Keywords: doping
      Classification: 2d, 22
      114 046
      Stachydrine in Leonurus cardiaca, Leonurus japonicus, Leonotis leonurus
      K. KUCHTA, R. B. VOLK, H. W. RAUWALD* (Department of Pharmaceutical Biology, University of Leipzig, Johannisallee 21-23, 04103 Leipzig, Germany, rauwald@rz.uni-leipzig.de)

      Pharmazie 68, 534-540 (2013). Detection and quantification by instrumental HPTLC and 1H-qNMR analyses. HPTLC of stachydrine on silica gel with methanol - dichloromethane - 25 % ammonia 823 with chamber saturation for 10 min in the horizontal developing chamber. The developing distance was 8.5 cm. Derivatization by dipping in Vagujfalvi solution (Wagner et al. 1983). Stachydrine was detected as red zone on yellow background. Quantitative determination by absorbance measurement at 517 nm. The method was selective with no other Dragendorff-positive constituents detected between hRF 45 - 60. The LOD was below 250 ng/zone. The results for the stachydrine content in the samples evaluated via peak height and peak area were in high accordance with independently performed 1H-qNMR measurements.

      Keywords:
      Classification: 22