JAOAC 85, 1015-1020 (2002). HPTLC and TLC on silica gel with ethyl acetate - isopropanol 9:5:4 cimetidine and famotidine and with ethyl acetate - methanol - 20% NH3 5:1:1 for ranitidine hydrochloride. Quantitation by densitometry at 218, 265, and 313 nm respectively. Simple, accurate, and rapid method.

J. Planar Chromatogr. 16, 45-47 (2003). HPTLC of cyproterone acetate and ethinylestradiol on spherical silica gel with cyclohexane - ethyl acetate 3:2 in a saturated chamber at 248C. Densitometry of cyproterone acetate at 284 nm and of ethinylestradiol at 220 nm. Quantitation by densitometry. The suitability of this HPTLC method was proved by validation of precision and accuracy; it can be used as a more effective option than other chromatographic techniques in routine quality control. Simple, reproducible, reliable, rapid, and accurate method.

Proc. Intern. Symp. on Planar Separations Plan. Chrom. 111-121 (2003). TLC of 14C-labeled 6a-hydroxytaxol and 4-hydroxytolbutamide on silica gel with toluene - acetone - formic acid 60:39:1 in a horizontal chamber, separation of 6b-hydroxy-testosterone on silica gel with dichloromethane - acetone 4:1.After drying the plates were placed in contact with a phosphor imaging plate (IP) for 12 h. The amount of unchanged drug and metabolites were determined using a photo Film.

J. Pharmaceut. Biomed. Analysis 31, 1185-1189 (2003). TLC on silica gel with chloroform - acetone 9:1 in an unsaturated chamber. Quantitation by densitometry at 254 nm. Comparison of TLC method with reversed phase HPLC analysis.

J. Planar Chromatogr. 17, 132-136 (2004). TLC and HPTLC of pravastatin, compactin and by-products (e. g. epi-pravastatin sodium salt and pravastatin-lactone) on silica gel in a twin-trough chamber with toluene - dichloromethane - tetrahydrofuran 23:1:1 for samples from ketone reduction and toluene - acetone - glacial acetic acid 20:30:4 for samples from compactin hydroxylation. Quantitative determination by reflectance measurement at 275 and 238 nm respectively.

J. Liq. Chrom. Rel. Technol. 27, 2047-2056 (2004). TLC of bromhexin on silica gel with n-butanol - glacial acetic acid - water 260:77:75 in a twin-trough chamber after at least 3 h of saturation. Quantitative determination at 325 nm by absorbance measurement. The method is selective, precise, and accurate and can be used for routine analysis of pharmaceutical preparations in pharmaceutical industry quality control laboratories.

IPC 56th 2004, Abstract No. GP-5. Simultaneous HPTLC determination of amlodipine and atenolol on silica gel with ethyl acetate - methanol - ammonia 60:40:3. Quantitative determination by scanning at 254 nm. The method was found linear in the range of 0.5 – 5.0 mg/mL amlodipine and 5.0 mg – 50 mg/mL atenolol. Recovery was 98.11 – 101.5 % for both of the compounds. The method was validated for accuracy, precision, linearity, specificity, LOD, and LOQ.

J. Planar Chromatogr. 17, 224-228 (2004). TLC of fluvoxamine and moclobemide on silica gel in horizontal chambers with benzene - acetone - ethanol - 25 % ammonia 9:7:2:1. Densitometric detection and quantification were performed at 249 nm and 236 nm, respectively. The range of linearity was 1 - 10 µg per spot; the RSD was less than 2.5 % for densitometry and less than 5.1 % for videodensitometry.