J. Planar Chromatogr. 16, 36-44 (2003). HPTLC of diclofenac and acetaminophen (paracetamol) in 10 different tablet formulations on silica gel, prewashed with methanol, with chloroform - methanol - ammonia 40:100:1 with chamber saturation. Densitometry at 277 nm. For estimation of acetaminophen a simple colorimetric method, involving reaction with sodium nitrite in acid, then treatment with alkali to produce the 3-nitroacetaminophane anion (yellow color), was validated and used. The intensity of the yellow color, monitored at 430 nm, was found to be linearly dependent on acetaminophen concentrations in the range 5-30 µg/ml.

J. Liq. Chrom. & Rel. Technol. 26, 3307-3314 (2003). HPTLC of rosiglitazone( (+/-)-5-[4-[2-[N-methyl-N-(2-pyridinyl)amino]-ethoxy]benzyl]-2,4-thiazolidinedione maleate) on silica gel with chloroform - ethyl acetate - 25% NH3 50:50:1. Detection and quantitation by densitometry in the reflectance/absorbance mode at 240 and 245 nm. Precision expressed as mean RSD was 3.58 and 2.76% for 240 nm, and 8.23 and 6.56% for 254 nm; mean recoveries from the fortified samples ranged from 89.48% to 99.38% for 240 nm, and from 89.05% to 100.89% for 254 nm. The mean recoveries from tablets were 101.95% to 103.2% for assays at 240 and 254 nm, respectively. New, simple, rapid method.

CBS 92, 1-3 (2004). HPTLC of cinchocaine hydrochloride from suppositories on silica gel with 1-butanol - toluene - ethanol - water - 100 % acetic acid 10:8:7:4:1 over 30 mm followed by heating at 110 °C for 10 min. Quantitative determination by fluorescence measurement at 313/>400 nm.Precision is 2 % and recovery 101 %.

Indian Drugs 41 (3), 149-152 (2004). HPTLC on silica gel with toluene - ethyl acetate 1:24. Quantitative determination by absorbance measurement at 260 nm. The linearity range is 100-500 µg/µL and recovery is 100.7 %. The method was validated and compared with HPLC. The results were comparable. Advantages of HPTLC in terms of handling many samples. Thus, a simple, fast and precise HPTLC method was developed for quantification of ebastine in tablets.

J. Planar Chromatogr. 17, 75-78 (2004). HPTLC of montelukast sodium (1-[[[(1R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyk)phenyl]-propyl]thio]methyl] cyclopropane acetic acid monosodium salt) and nimesulide (N-(4-nitro-2-phenoxyphenyl)methane sulfonamide or 4-nitro-2-phenoxymethanesulfonanilide) as internal standard on pre-washed silica gel with toluene - ethyl acetate - glacial acetic acid 60:34:1 in a twin-trough chamber. Quantitative determination at 344 nm.

J. Planar Chromatogr. 17, 383-387 (2004). TLC of fenbufen, ibuprofen, ketoprofen, diclofenac sodium, mefenamic acid, and tiaprofenic acid on silica gel by ascending and horizontal techniques, and on RP-18 in horizontal chambers. Good separation was achieved on silica gel by horizontal development with chloroform - methanol - 25 % ammonia 67:25:8; reversed phase chromatography on RP-18 with 0.15 mol/L phosphate buffer, pH 5.73 - 10 % CTMA-Br (N-cetyl-N,N,N-trimethylammonium bromide) in methanol 7:13 enabled better separation of the six drugs. Detection under UV light at 254 nm - for ibuprofen detection was best achieved after normal phase chromatography with 20 % aqueous sodium carbonate solution. A simple videodensitometric procedure was developed and validated. RSD for quantitation of fenbufen was 2.44 - 3.10 %.

IPC 56th 2004, Abstract No. GP-3. Simultaneous HPTLC determination of valdecoxib and tizanidine in tablets on silica gel with n-butyl acetate - formic acid - chloroform 7:3:2. Quantitative determination by densitometric scanning at 283 nm. The Rf values of valdecoxib and tizanidine were 0.78 and 0.39 respectively. Linearity range was 200 - 1000 ng/spot and 60 - 300 ng/spot respectively. Mean recovery for both of the compounds was 99.57 – 101.28 %. The method was validated for accuracy, precision, linearity, LOD, and LOQ.

J. Planar Chromatogr. 18, 155-159 (2005). TLC of repaglinide on RP-8 with acetonitrile - phosphate buffer pH 6.0 3:2. Quantitative determination by absorbance measurement at 225 nm. Calibration in the range of 0.6-3.6 µg was linear with a good correlation coefficient (r = 0.998 +/- 0.001). Limits of quantitation and detection were 0.27 µg and 0.08 µg, respectively.