J. AOAC Int. 81, 333-339 (1998). Contemporary TLC or HPTLC combines the techniques' inherent advantages which include high sample throughput, simultaneos processing of standards and samples, flexibility, easy postchromatographic visualization techniques, and the ability to handle complex or crude samples with minimum sample clean-up - with improved selectivity, sensitivity, and accuracy. It is a very economical chromatographic technique that competes with and complements HPLC. Development and validation of procedures can be performed rapidly in full accordance with all current international guidelines.

J. Chinese Trad. Patent Med. (Zhongchengyao) 22 (4), 265-266 (2000). TLC on silica gel with toluene - acetone - NH3 conc. - ethanol 30:20:1:3. Detection under UV 254 nm. Quantitation by densitometry at 254 nm

Chinese J. Pharm. Anal. (Yaowu Fenxi Zazhi) 22 (2), 155-158 (2002). A review with 30 references on the title topic, including chiral derivative reagents, chiral mobile phase additives, chiral stationary phase, etc. stressing on chiral stationary phase.

59th Indian Pharmaceutical Congress F-95, 414, (2007). HPTLC of granisetron hydrochloride on silica gel aluminium plates with chloroform - methanol 4:1, with 0.1 mL of ammonia. The hRf value of granisetron hydrochloride was 42. Densitometry in absorbance mode at 301 nm. Linearity was between 400 and 1600 ng/zone. The limit of detection and quantification was 80 ng and 160 ng/zone, respectively. The drug was subjected to acid and alkali hydrolysis, oxidative and thermal degradation. The degration products were well separated from the main compound.

J. Sep. Sci. 37, 2675-2681 (2014). HPTLC of the acidic catecholamine metabolites (1) 3,4-dihydroxymandelic acid, (2) epinephrine, (3) vanillylmandelic acid, (4) 3,4-dihydroxyphenylacetic acid and (5) homovanillic acid in human urine on RP-18 with citrate buffer (pH 3.0) - methanol - formic acid 48:2:5. Detection by spraying with 0.02 % 2,2-diphenyl-1-picrylhydrazyl radical solution in ethanol. Quantification by digital imaging processing. The hRF values of (1) to (5) were 84, 65, 59, 47 and 22, respectively. Linearity was in the range of 30-150 ng/zone for (1), (2) and (4), 90-450 ng/zone for (3) and 60-300 ng/zone for (5). The intermediate intra-day and inter-day precisions were below 3 % (n=3) for (1) to (5). The LOD and LOQ were 33 and 36 ng/zone for (1), 36 and 42 ng/zone for (2), 103 and 120 ng/zone for (3), 13 an 17 ng/zone for (4) and 45 and 54 ng/zone for (5), respectively. Recoveries for the compounds were between 94.6 and 105.7 %.

J. Planar Chromatogr. 20, 463-475 (2007). TLC of chlorpromazine hydrochloride, trifluoperazine dihydrochloride, promazine hydrochloride, and doxepin hydrochloride on silica gel with 1-butanol - aqueous ammonia solution 5:1 or cyclohexane - acetone - diethylamine 8:1:1 after saturation with mobile phase vapor. Detection by inspection under UV light at 254 nm. Scanning densitometry was performed at 254 nm and at the wavelengths of maximum absorbance of the substances.

Japanese J. of Clin. Pathology (Rinsho Byori) 32, 425-428 (1984). TLC of urinary vanillyl mandelic acid on DEAE cellulose with butanol - pyridine - water 14:4:5. Semi-quantification by comparing the color of the spots.

59th Indian Pharmaceutical Congress F-55, 402, (2007). HPTLC of metformin hydrochloride on silica gel with methanol - chloroform - ammonium acetate 6:3:1. Densitometry at 236 nm. The method has a range from 100 - 300 ng/zone. The limit of detection and quantification was 25 ng and 100 ng/zone, respectively. The method was applied for analysis of metformin hydrochloride in multi-component formulations containing glipizide, gliclazide and glibenclamide as well as in serum.