Indian Drugs 42 (7), 424-427 (2005) HPTLC of fexofenadine HCl from tablet dosage form on silica gel with dichloromethane - methanol 13:7. Quantitative determination by absorbance measurement at 260 nm. The linear detector response was observed between 0.2 and 1.0 µg. The method was validated to determine its accuracy and precision. The LOD was found to be 0.08 ng/µL, LOQ was 0.02 ng/µL. The recovery was carried out by standard addition method and was found to be 100.82 %.

J. Sep. Sci. 26, 1359-1362 (2003). HPTLC of tramadol and chlorzoxazone (internal standard) on silica gel with ethyl acetate - methanol 7:1 and 1 drop of ammonia. Quantitative determination by absorbance measurement at 275 nm. Linearity of determination of levofloxacin is between 1.0 and 2.5 µg and its average percentage recovery is 104.6 %.

Indian Drugs 44(1), 43-47 (2007). HPTLC of beta-sitosterol in methanolic extracts of powdered Cynodon dactylon (Linn.) Pers., on silica gel with chloroform - toulene 19:1. Detection with Libermann-Burchard reagent. Quantitative determination by densitometry at 366 nm. Beta-sitosterol response was linear over the range of 40 µg/mL to 90 µg/mL. The amount of beta-sitosterol in the whole plant powder of Canodon dactylon (Linn.) Pers was found to be 0.60 mg. The validated HPTLC method can be used for routine quality control of Cynodon dactylon (Linn.) Pers. whole plant powder and quantification of beta-sitosterol.

Indian J. Pharm. Sci. 68 (6), 790-793 (2007). HPTLC of carvedilol in bulk drug and pharmaceutical formulations, on silica gel with ethyl acetate - toluene - methanol 2:8:7. Quantitative absorbance measurement at 242 nm. The hRf value of carvedilol was 65. The method was found to be linear over the concentration range of 50-300 ng/spot with recovery of 98.3-101.1%.The method was validated for accuracy and precision. Comparison with an HPLC method showed the HPTLC method to be advantageous regarding sample throughput.

Pharmazie 60, 110-114 (2005). TLC of two glyceride derivatives of mefenamic acid (“3a and 3b“) on silica gel with hexane - ethyl acetate 5:1. Detection by exposure to iodine vapors.

extract and its traditional formulation from rat plasma; application to pharmacokinetics. J. Planar Chromatogr. 27, 23-28 (2014). HPTLC of marmelosin in plasma on silica gel with toluene - ethyl acetate - glacial acetic acid 70:30:1. Quantitative determination by absorbance measurement at 310 nm. The hRF value for marmelosin was 57. Linearity was between 1 and 150 µg/mL. The intermediate/interday/intra-day precisions were below 6 % (n=6). The LOD and LOQ for marmelosin was 150 ng/mL and 1000 ng/mL, respectively. Recovery was in the range of 90.9-106.1 %.

(Screening of halazepam, a new antianxiety agent.) Fresenius Z. Anal. Chem. 321, 359-362 (1985). Use of TLC as a sensitive screening method for 1,4-benzodiazepine derivative (halazepam). After hydrolysis TLC of 2 (2,2,2-trifluoroethyl) amino-5-chloro-benzophenone on silica with toluene. After photolytic desalkylation and diazotation spraying with Bratton-Marshall reagent.

J. Chromatogr. 442, 459-463 (1988). One- and two-dimensional TLC of thyrostatics on silica with chloroform - acetone 7:3 for the first direction and ethyl acetate for the second. Detection by spraying with palladium (II)-calcein reagent and inspection under UV 365 nm. Identification by comparison of Rf values in different solvent systems. Detection limit, 200 ppb for 6-methyl-2-thiouracil.