Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
  • Browse and search by CBS classification: Select one of the 38 CBS classification categories where you want to search by a keyword
  • Keyword register: select an initial character and browse associated keywords
  • Search by CBS edition: Select a CBS edition and find all related publications

Registered users can create a tailor made PDF of selected articles throughout CCBS search – simply use the cart icon on the right hand of each abstract to create your individual selection of abstracts. You can export your saved items to PDF by clicking the download icon.

      78 031
      Supercritical fluid chromatography of fish, shark and seal oil
      C. BORCH-JENSEN, J. MOLLERUP*, (*Dept. Chem. Eng., Tech. Univ. Denmark, 2800 Lyngby, Denmark)

      Chromatographia 42, 252-258 (1996). TLC of lipid groups in marine oils on silica with petrol ether - ether - acetic acid 170:30:3. Detection by spraying with 5% sulfuric acid in methanol and heating at 110°C. Identification by retention factors. Preparative TLC of shark liver oil lipids using the same system. SFC of the TLC fractions after elution.

      Classification: 4d, 11c
      82 049
      (Analysis of a-linolenic acid in silkworm pupa oil
      P. LU (Lu Ping)*, B. LAI (Lai Binglin), X. YAN (Yan Xiaolin), Y. WANG (Wang Yingqiang), (*Dept. Biochem., Beijing Med. Coll. PLA, Beijing 100071, P.R. China)

      Chinese J. Pharm. Anal. (Yaowu Fenxi Zazhi) 18, 390-393 (1998). TLC of the methyl esterification products on silica with petroleum ether - ether- acetic acid 35:15:1. Detection by exposure to iodine vapor. Evaluation of the completeness of esterification by finger print techniques. Quantitation by GC.

      Keywords:
      Classification: 4d, 11a
      91 012
      Fully on-line TLC/HPTLC with diode-array detection and continuous development
      S. NYIREDY, (Res. Inst. for Med. Plants, H-2011 Budakal·sz, P. O. Box 11, Hungary)

      Part 1: Description of the method and basic possibilities. J. Planar Chromatogr. 15, 454-457 (2002). HPTLC and TLC of a test dye mixture on silica gel in a special horizontal chromatographic chamber. Detection with a new TLC/HPTLC scanner with optical fibers, a special fiber interface, and a diode-array detector working in the range of 197 to 800 nm with an average optical resolution better than 2.0 nm. Description of a novel liquid chromatographic technique, fully on-line TLC/HPTLC. The method integrates the idea of the continuous development, continuous-flow TLC, and diode-array detection. The principle of the method, the design of the prototype apparatus, and the fundamental advantages of the novel technique are described.

      Keywords:
      Classification: 4d
      93 164
      (Study of the quality standard of Ganmaoyankeling tablets
      Y. ZHENG (ZHENG YI)* (*Pingshan Pharm. Factory, Fuzhou, Fujian 350003, P. R. China)

      J. Chinese Trad. Patent Med. (Zhongchengyao) 11, 885-887 (2004). TLC on silica gel with 1) n-butanol - 3 M NH4OH - ethanol 5:2:1, 2) toluene - ethyl acetate - formic acid 5:4:1. Detection 1) under UV 254 nm, 2) by spraying with 10 % FeCI3 in ethanol. Identification by fingerprint techniques. Quantitative determination of quercetin by HPLC.

      Classification: 4d, 32c
      103 018
      The Use of Thin-Layer Chromatography with Direct Bioautography for Antimicrobial Analysis
      Irena CHOMA (Department of Chromatographic Methods, M. Curie-Sklodowska University, Lublin, Poland)

      LC-GC Europe 18, 482-488 (2005). Contact Bioautography: Antimicrobials diffusion from a TLC plate to an inoculated agar plate.The chromatogram is placed face down onto the inoculated agar layer and left for some minutes or hours for diffusion. After removing the plate the inhibition zones are observed on the agar surface in the places where the spots of antimicrobials are stuck to the agar. The method resembles a disk assay. Immersion Bioautography: The chromatogram is covered with a molten, seeded agar medium. After solidification, incubation and staining (usually with tetrazolium dye) the inhibition or growth bands are visualized. Direct Bioautography: A developed plate is dipped in the suspension of microorganisms growing in a suitable broth or this suspension is sprayed onto the plate. The plate is incubated and microorganisms grow directly on it. It can be performed with Photobacterium phosphoreum (Vibrio fischeri) suspension. Bioautography systems and coupling possibilities are presented.

      Classification: 4e
      104 009
      Direct quantitative bioanalysis of drugs in dried blood spot samples using a thin-layer chromatography mass spectrometer interface
      P. ABU-RABIE*, N. SPOONER (*PreClinical Development Drug Metabolism and Pharmacokinetics, GlaxoSmithKline Research and Development, Park Road, Ware, Hertfordshire, SG12 ODP, United Kingdom; Paul.2.Abu-Rabie@gsk.com)

      Anal. Chem. 81, 10275-10284 (2009). Direct quantitative bioanalysis of drugs from dried blood spot samples using a TLC-MS interface with or without HPLC separation. The method gave acceptable sensitivity, linearity, accuracy, and precision data for bioanalytical validations. The direct elution technique was shown to increase assay sensitivity for a range of analytes. Investigations were performed to optimize extraction time, minimize sample-to-sample carry-over, and compare chromatographic performance. On the basis of this preliminary assessment, it has been demonstrated that this TLC-MS interface has the potential to be an effective tool for the direct analysis of drugs in dried blood samples at physiologically relevant concentrations.

      Classification: 4e
      107 031
      TLC/HPTLC-ELSD-MS coupling
      F. BRETIN, F. MAQUIN* (*Sanofi-Aventis, Centre de Recherche, 13 quii Jules Guesde, 94403 Vitry-sur-Seine, France, francis-maquin@sanofi-aventis.com)

      CBS 105, 2-4 (2010). TLC and HPTLC of reaction samples from small molecule lead development, on silica gel with mixtures of methanol and dichloromethane/ethyl acetate or ethyl acetate and heptane/cyclohexane (ratios depending on the compound mixtures). Detection with primuline or berberine reagent. Direct elution into the MS with the TLC-MS interface. Substances not detected by DAD can successfully be measured by ELSD detection coupled to TLC.

      Classification: 4e
      112 048
      TLC-direct bioautography for determination of antibacterial activity of Artemisia adamsii essential oil
      G. HORVATH, K. ACS (*University of Pécs, Medical School, Department of Pharmacognosy, Hungary, gyorgyi.horvath@aok.pte.hu)

      J. AOAC Int. 96, 1209-1213 (2013). TLC of thujone (1) and 1,8-cineole (2) in the leaves of Artemisia adamsii essential oil on silica gel with toluene - ethyl acetate 93:7. Detection by dipping into vanillin - sulfuric acid reagent, followed by heating at 90 ºC for 3 min. The hRf values for (1) and (2) were 56 and 45. Bioautography by dipping into S. aureus suspension for 10 s. After drying for 2 min followed by incubation at 37 ºC for 17 h the plates were dipped in an aqueous solution of MTT (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide 50 mg/80 mL) for 10 s and incubated at 37°C for 2 h. Inhibition zones appeared as pale yellowish zones against blue background.

      Classification: 4e, 15a