J. Planar Chromatogr. 2, 336-345 (1989). Approaches to increasing the separation potential of TLC and to interface TLC to multidimensional detectors yielding structural information for separated zones are made from the perspective of current practices, including two-dimensional forced flow TLC, unidimensional multiple development and multimodal separations obtained by interfacing column chromatographic techniques and supercritical fluid extraction.

J. Planar Chromatogr. 6, 21-28 (1993). Description of on-line coupling of HPLC, solid phase extraction (OSP), and TLC. The technique opens up new possibilities in the field of multidimensional chromatography of complex samples. Using the OSP-2 apparatus the HPLC eluent is exchanged by the inclusion of an on-line solid phase extraction step between the two chromatographic processes. This on-line coupling has been used for the quantitative determination of 4(5)-methylimidazole in caramel.

J. Chinese Trad. Patent Med. (Zhongchengyao) 18 (1), 20-21 (1996). TLC of hesperidin on silica with 1) the upper phase of ethyl acetate - formic acid - water 7:1:3, 2) chloroform - methanol - acetone - NH3 10% 3:3:3:1. Detection 1) by spraying with 10% AlCl3 in ethanol and under UV 365 nm, 2) by spraying with 0.5% ninhydrin in ethanol and heating at 105°C for 5 min. Identification and quantification by comparison with standards.

J. Planar Chromatogr. 11, 438-440 (1998). Proposition of a new variant of two-dimensional planar paper chromatography, including the study of the possibility of two-dimensional chromatography with paper chromatography in the first stage and a TLC plate in the second stage. This procedure used for the separation of a lipophilic dye mixture with toluene as mobile phase needs 2 h. When conventional two-dimensional paper chromatography is used the duration exceed 3.5 h.

J. Chinese Trad. Patent Med. (Zhongchengyao) 25 (12), 964-967 (2004). TLC on silica gel with 1) chloroform - methanol - acetone - formic acid - water 54:14:8:6:1, 2) toluene (saturated with water) - ethyl acetate - formic acid 5:4:1, 3) cyclo hexane - ethyl acetate 5:1. Detection 1) by iodine vapor, 2) under UV 365 nm. Identification by fingerprint techniques. Quantitative determination of acetaminophen and chlorogenic acid by HPLC.

J. Chromatogr. A 1145 (1-2), 222-228 (2007). Pre-fractionation of cis and trans-fatty acids by silver-ion TLC (Ag-TLC) and other methods (silver-ion SPE (Ag-SPE) or HPLC) allows accurate determination of the isomeric profile but is not essential to achieve quantification of total trans-18:1 isomers nor to determine the level of vaccenic (trans-11 18:1) acid in dairy fat. Comparison of different GLC methods suitable to measure the total of trans-18:1 isomers, vaccenic acid and trans-18:1 acid isomeric distribution in milk fat. Pre-separation of cis- and trans-18:1 isomers by Ag-TLC followed by GLC analysis under optimal conditions was selected as the reference method.

Anal. Bioanal. Chem. 389, 827–834 (2007). A total extract of hen egg yolk is used as phospolipid mixture to demonstrate the capabilities. TLC of phosphatidylcholine, lysophosphatidylcholine, sphingomyelin, phosphatidylethanolamine, lysophosphatidylethanolamine and phosphatidylinositol on silica gel with chloroform - ethanol - water - triethylamine 5:5:1:5. Detection under UV 366 nm after spraying with primuline (Direct Yellow 59) reagent. Direct coupling MALDI-TOF MS and TLC can be easily implemented on commercially available MALDI-TOF devices. Roughly clean spectra without major contributions from fragmentation products and matrix peaks were obtained. This approach was sensitive enough to detect the presence of phospholipids at levels of less than 1 % of the total extract.

Rapid Commun. Mass Spectrom. 23, 2597-2604 (2009). RP-TLC of pharmaceutical formulations containing paracetamol, ephedrine, codeine, and caffeine on hydrocarbon-impregnated silica with methanol - water 1:1. Detection by desorption electrospray ionization (DESI) combined with ion mobility mass spectrometry (IM-MS). The limit of detection was 9, 16, 34, 239 and 225 µg/cm2 for codeine, caffeine, ephedrine and paracetamol, respectively.