Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
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      130 004
      Identification of acetylcholinesterase inhibitors in water by combining two-dimensional thin-layer chromatography and high-resolution mass spectrometry
      Lena STÜTZ*, W. SCHULZ, R. WINZENBACHER (*Laboratory for Operation Control and Research, Zweckverband Landeswasserversorgung, Langenau, Germany;

      J Chromatogr A, 1624, 461239 (2020). Samples were chemical standards of acetylcholinesterase (AChE) inhibitors (azamethiphos, caffeine, donepezil, galanthamine, methiocarb-sulfoxide, paraoxon-ethyl) and of neurotoxic compounds, as well as drinking or contaminated water samples enriched through solid phase extraction. HPTLC on spherical silica gel (pre-washed twice by 20 min immersion in isopropanol, heated 20 min at 120 °C before and after pre-washing with acetonitrile). First separation (preparative TLC) with automated multiple development (16 steps). Effect-directed analysis for AChE inhibitors by immersion (speed 5 cm/s, time 1 s) into enzyme solution, incubation 5 min at 37 °C and immersion into substrate solution (indoxyl acetate 2 % in methanol); visualization under UV 366 nm. Active zones from untreated layers were eluted through the oval head of a TLC-MS interface to a second plate for a second separation with a panel of other mobile phases. Bands of interest were eluted from the second layer with water through the oval elution head of the TLC-MS interface pump, into a RP18 liquid chromatography guard column, followed by a quadrupole time-of-flight mass spectrometer. Full scan mass spectra (m/z 100–1200) were recorded in negative and positive modes using electrospray ionization (and collision-induced dissociation for MS2). Among the water contaminants, lumichrome (riboflavin photolysis product), paraxanthine and linear alkylbenzene sulfonates were identified as AChE inhibitors.

      Classification: 3d, 4d, 4e, 22, 29b, 35d, 37c
      103 170
      Analysis of waxes on historical samples by thin-layer chromatography
      Iva REZIC*, D. KRSTIC, L. BOKIC (*Laboratory of Analytical Chemistry, Department of Applied Chemistry, Faculty of Textile Technology, University of Zagrab, Prilaz baruna Filipovica 28a, 10000 Zagreb, Croatia;

      J. Planar Chromatogr. 22, 171-173 (2009). TLC of waxes (carnauba, candellia, lanolin, japanese, spermaceti, bees, and paraffin) on silica gel with petroleum ether - diethyl ether - acetic acid 90:10:1 with chamber saturation. Detection under UV 254 nm.

      Classification: 35d
      73 171
      TLC study of the compound groups present in bituminous substances
      L. MARYNOWSKI, M. FABIANSKA*, A. JOHN, (*Laboratory of Geochemistry, Dept. of Geochem., Min., and Petrogr., Fac. of Eath Sci., Silesian Univ., PL-41200 Sosnowiec, 60 Bedzinska Str., Poland)

      J. Planar Chromatogr. 7, 122-125 (1994). TLC of extracts of bituminous substances on silica with dichloromethane. 11 different detection reagents were used for different functional groups (e.g. Dragendorff's reagent for quinolines, acridines, pyridines; UV for PAHs; bromocresol green for carboxylic acids). The samples were examined for the occurrence of basic, neutral, and acidic heterocyclic nitrogen compounds, aromatic hydrocarbons, and oxygen compounds.

      Classification: 35d
      108 148
      Cleaning validation using HPTLC
      Birgit BOECKEL (Bayer Weimar GmbH & Co. KG, Product Supply Pharma, QC Raw Materials, Doebereiner Str. 20, 99427 Weimar, Germany,

      CBS 107, 2-4 (2011). To ensure effective cleaning of the reaction vessels in pharmaceutical production wool swabs are used to swipe a defined area of the vessel. The wool swabs are extracted with chloroform and the extracts are applied as rectangles of 4x3 mm. HPTLC on silica gel with toluene - ethyl acetate 3:2 with chamber saturation for 10 minutes. Identification of substances by densitometric spectra recording between 200-350 nm followed by 3-level calibration. Detection by spraying or immersion in methanol - sulfuric acid 9:1 and heating for 5 min at 105 °C. Evaluation under visible light and UV 366 nm.

      Classification: 35d
      74 156
      Determination of the age of ballpoint pen ink by gas and thin-layer chromatography using densitometry
      V.N. AGINSKY, (Forensic Sci. Cent., Ministry of the Interior. 22 Raspletina Str., Moscow 12 3060, Russian Federation)

      J. Chromatogr. 678, 119-125 (1994). TLC of ink components on silica with ethanol - acetone - hexane 1:5:20. Evaluation by plotting the calibrated values of the standards against the samples being tested. Determination of the volatile components of the ink by GC.

      Classification: 35d
      115 028
      Characterization of Pterocarpus erinaceus kino extract and its gamma-secretase inhibitory properties
      S. HAGE, Serena STANGA, Claudia MARINANGELI, J.-N. OCTAVE, Ilse DEWACHTER, Joëlle QUETIN-LECLERCQ, P. KIENLEN-CAMPARD* (*Institute of Neuroscience, Université catholique de Louvain, 1200 Brussels, Belgium;

      Journal of Ethnopharmacology 163, 192-202 (2015). TLC of the aqueous extract (crude vs. after tannin removal on a polyamide column) of the kino (red hydrosoluble exudate) of Pterocarpus erinaceus on silica gel with s-butanol – water – acetic acid 14:5:5. Detection with vanillin-hydrochloric acid reagent revealed catechic tannins and related polyphenols as dark pink zones. These compounds showed hRfs between 0 and 40, and above 60 in the case of the crude extract, whereas they almost did not appear in the tannin-free fraction. The extracts were also submitted to HPLC-HRMS, allowing the identification of epicatechin monomer in both extracts and of oligomers in the crude extract only.

      Classification: 8a, 32e, 35d
      77 212
      Fractionation of coal tar pitch by planar chromatography for the characterization of large molecular mass materials
      A.A. HEROD*, R. KANDIYOTI, (Dept. of Chem. Eng. and Chem. Technol., Imperial Coll., Univ. of London, London SW7 2BY, UK)

      J. Planar Chromatogr. 9, 16-24 (1996). TLC of a coal tar pitch on silica with pyridine followed by N,N-dimethylformamide (I) and THF followed by toluene as solvent system after chamber saturation for 30 min; first development 2 - 3 cm, after removal and drying development in the second solvent for a further 2 - 3 cm beyond the first solvent front. Separated sample fractions were examined by size exclusion chromatography, UV-absorbance, and UV-fluorescence spectroscopy.

      Classification: 35d
      119 109
      Separation of pigment formulations by high-performance thin-layer chromatography with automated multiple development
      Constanze STIEFEL, Sylvia DIETZEL, M. ENDRESS, Gertrud E. MORLOCK* (*Justus Liebig Univ. Giessen, Chair of Food Sci., Inst. of Nutritional Sci., and Interdisciplinary Res. Center (IFZ), Heinrich-Buff-Ring 26-32, 35392 Giessen, Germany)

      J. Chromatogr. A 1462, 134-145 (2016). Development of simple method for the separation of different colored pigment formulations used in the printing materials on food packaging to control the quality and safety of the package. HPTLC on silica gel by automated multiple development with a 9-step gradient based on ethyl acetate, methanol and water, and ending with toluene. Good resolution of differently soluble constituents of the pigment formulation like additives and coating materials. The results obtained by multi-detection allowed a first assignment of the differently detectable bands to particular chemical substance classes, enabled the comparison of different commercially available pigment batches and revealed substantial variations in the composition of the batches. Characterization of single unknown pigment constituents by HPTLC-MS and HPTLC combined with ATR-FTIR. The new HPTLC method for routine quality control for incoming pigment batches and monitoring of internal pigment production processes secures a consistent pigment composition, resulting in consistent ink quality. Hyphenation of HPTLC with the Aliivibrio fischeri bioassay revealed information on the toxicological potential of different pigment compounds which helps guarantee consumer safety, especially in regard to readily permeable pigment components.

      Classification: 4e, 35d