Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

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      129 071
      Comparison of high-performance thin-layer with overpressured layer chromatography combined with direct analysis in real time mass spectrometry and direct bioautography for tansy root
      Ágnes M. MÓRICZ*, T.T. HÄBE, P.G. OTT, G.E. MORLOCK
      (*Plant Protection Institute, Centre for Agricultural Research, Hungarian Academy of Sciences, 1022 Budapest, Hungary; moricz.agnes@atk.hu)

      J Chromatogr A, 1603, 355–360 (2019). Samples were ethyl acetate root macerates of fully flowered Tanacetum vulgare (Asteraceae). HPTLC on silica gel (classical irregular particles vs. Lichrosphere with spherical particles) previously washed with methanol, dried for 5 min at room temperature, perimeter-sealed with a polymer coat, and heated for 30 min at 100 °C. Separation with toluene or with toluene – n-hexane 7:3, in classical capillary flow or in OPLC (overpressured layer chromatography). For OPLC, off-line infusion was used (closed mobile phase (MP) outlet, automatically stopping development); external pressure 50 bar, rapid MP flush 175 and 350 µL, MP flow rate 250 and 500 µL/min, 1830 and 3475 µL MP, development time 446 s and 424 s. Derivatization by immersion into vanillin – sulfuric acid reagent, followed by 5 min heating at 110 °C; or into PABA reagent (500 mg p-aminobenzoic acid, 18 mL glacial acetic acid diluted, 20 mL water, 1 mL o-phosphoric acid, 60 mL acetone), followed by 5 min heating at 140 °C. Effect-directed analysis using automated immersion: A) for free radical (DPPH•) scavengers; B) for activity against Gram-negative bacteria using Aliivibrio fischeri bioluminescence assay; C) for activity against Gram-positive bacteria with Bacillus subtilis bioassay. Four active polyynes were identified as hexadiynylidene-epoxy-dioxaspiro-decane (1), pontica epoxyde (nonene-triynyl-vinyl-oxirane) (2), tetradeca-triine-en-one (3) and trans-(hexadiynylidene)-dioxaspiro-decene (4), by hyphenating OPLC to quadrupole-orbitrap HRMS without eluent, using a DART interface (Direct Analysis in Real-Time, needle voltage 4kV, grid voltage 50 V, helium as gas, temperature 500 °C, full scan in positive ionization mode in m/z range 100-750). Polyynes (3) and (4) were coeluting in HPTLC but not in OPLC, demonstrating that (4) is not produced by oxidation during the DART-MS procedure. Separation with OPLC compared to HPTLC was performed in a shorter time and with better resolution at the same time. Layers with spherical particles gave higher resolution; zone distortions occurring in OPLC due to dissolved air in MP were prevented by previous MP sonication.

      Classification: 3b, 3d, 4e, 5a, 8b, 9, 32e
      125 031
      Impregnated silica-based layers in thin layer chromatography
      Anna SOBANSKA (Department of Analytical Chemistry, Faculty of Pharmacy, Medical University of Lodz, Muszynskiego 1, Lodz 90-151, Poland, anna.sobanska@umed.lodz.pl)

      J. Liq. Chromatogr. Relat. Technol. 43, 319-327 (2020). Review of impregnated agents used in TLC and their applications in analytical and medicinal chemistry. Impregnation with inorganic ions, chelating reagents, lipophilic substances, surfactants, chiral selectors and ionic liquids were discussed.

      Classification: 1b, 3b
      124 053
      Highly-porous diatom biosilica stationary phase for thin-layer chromatography
      J.A. KRAAI, G.L. RORRER*, A.X. WANG (*School of Chemical, Biological and Environmental Engineering, Oregon State University, Corvallis, OR 97331, USA, gregory.rorrer@oregonstate.edu)

      J. of Chromatogr. A 1591, 162-170 (2019). TLC of malachite green (1) and fast green (2) on diatom biosilica (a nanostructured, porous stationary phase composed of randomly-deposited biosilica frustules isolated from living cells of diatom Pinnularia sp.) instead of conventional silica gel with 1-butanol - ethanol - water 9:1:1 and 1-butanol - acetic acid - water 5:1:2. Diatom biosilica reduced the flow velocity and permeability constant by a factor two compared to silica gel and thus improved the resolution of (1) and (2). The theoretical plate height for both analytes was reduced ten-fold with 1-butanol - acetic acid - water 5:1:2, and the difference in retention time between malachite green and fast green was increased (ΔhRF 26) with 1-butanol - ethanol - water 9:1:1.

      Keywords:
      Classification: 3b
      112 011
      (Study on the preparation and application of barium fluoride particles used as the stationary phase in TLC-FTIR analysis) (Chinese)
      W. LIU (Liu Wei), H. WU (Wu Haijun), X. WANG (Wang Xiupeng), Q. ZHU (Zhu Qing), Y. KANG (Kang Yanguo), A. HE (He Anqi), SH. WENG (Weng Shifu), ZH. YANG (Yang Zhanlan), J. XIA (Xia Jinming), Y. XU (Xu Yizhuang)*, J. WU (Wu Jinguang) (*State Key Lab. of Rare Earth Mat. Chem. & Appl., Coll. of Chem. & Mol. Engineering, Peking Univ., Bejing 100871, China)

      Chem. J. of Chinese Univ. 34 (6), 1347-1352 (2013). TLC is widely applied as an analytical technique due to its distinguishing features like its intuitiveness, high performance, inexpensiveness, etc., however, gives insufficient qualitative information of the separated ingredients. On the contrary, FTIR is a strong technique in functional identification and qualitative analysis towards pure compounds rather than mixtures. TLC-FTIR combines the merits of both techniques and realizes in situ detection of the interested analytes. In the search for a stationary phase suitable for TLC-FTIR the processing procedure for barium fluoride particles was improved. The particle size was minimized to enhance separation performance and to attenuate the spectrum baseline elevation caused by the effect of light scattering. Preparation of barium fluoride particles by reaction of 100 mL of a 0.6 mol/L barium chloride solution and 150 mL of a 0.95 mol/L sodium fluoride solution. The resulting sediment was filtered, washed, and burned in a Muffle furnace at 600 °C for 3 hours, which produced particles with a size of approx. 100 nm. The TLC plates were coated by precipitation/evaporation method: 5 g barium fluoride powder and 50 mL distilled water were mixed to a suspension, which was poured into a vessel containing the basal gold-plated glass sheet placed horizontally. After complete evaporation of the liquid a barium fluoride TLC plate was obtained with a smooth, even and mechanically strong surface. Demonstration by TLC of rhodamine B and malachite green on the new barium fluoride plate with methanol – acetone 3:10 with chamber saturation for 30 min. In situ identification of the separated zones by microscopic reflection FTIR. The results indicated that TLC-FTIR based on barium fluoride plates has wide application prospect.

      Classification: 3b
      55 013
      Chinese Anal
      Z. MAO, Q. ZHANG

      Chem. (FENXI HUAXUE) 12, 455-458 (1984). (Chinese). (Studies on micellar solution as mobile phase in liquid chromatography. I. Use in thin-layer chromatographic separation of drugs). TLC of 33 drugs including sulfanilamides, vitamin B, antipyretics and adrenalines on polyamide with micellar aqueous solutions (SDS). Detection by various staining reagents and by UV.

      Classification: 3b, 32c
      59 019
      Neue wasserbenetzbare HPTLC RP-18 Fertigplatten
      W. JOST, H.E. HAUCK

      GIT Fachz. Lab. 12, 1221-1223 (1986). Neue wasserbenetzbare HPTLC RP-18 Fertigplatten. New HPTLC RP-18 pre-coated plates wettable by water.) Description of a new HPTLC precoated plate based on silica gel with a reduced degree of modification with octadecyl groups. This plate material is fully wettable with methanol - water mixtures between 0:100 and 100:0. Running times for 50 mm are between 14 and 40 minutes, whereby the maximum running times occur with the 50:50 mixture. Separations of nicotinic acid - isonicotinic acid, of analgesics and of alkaloids.

      Keywords:
      Classification: 3b, 22, 32b
      60 112
      Enantiomeric separation of N-carbamyl-tryptophan by thin-layer chromatography on a chiral stationary phase
      L.K. GONT, S.K. NEUENDORF, (INCELL Corp., 1600 W. Cornell, Milwaukee, WI 53211, USA)

      J. Chromatogr. 391, 343-345 (1987). TLC of N-carbamyl-D, L-tryptophan on silica containing a chiral stationary phase, 2S, 4R, 2'RS-4-hydroxy-1- (2-hydroxydodecyl) proline, and copper(II) with water - methanol system at reduced temperature. Detection by spraying with Ehrlich's reagent and heating at 105 °C for 5 min Sensitivity, 100 mg/mL.

      Keywords:
      Classification: 3b, 18a
      65 024
      Variation of stationary phases in planar chromatography
      T.J. GOOD*, A.G. TAKETOMO, (*CERA, 14180F Live Oak Ave., Baldwin, Park, CA 91706, USA)

      J. Planar Chromatogr. 2, 383-386 (1989). TLC separation of dyes and plant pigments on different modified silica stationary phases (cyclic diols, cyanopropyl, carboxylic ester) with toluene, isooctane - methanol - diethylether 7:1:2 as mobile phase and three methods of development - traditional vertical tank, experimental horizontal sandwich apparatus and an experimental over-pressure device. - The variation of the stationary phase can be used to gain selectivity advantages in chromatographic separations.

      Classification: 3b, 30