Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
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      127 028
      Estrogenic activity of food contact materials—evaluation of 20 chemicals using a yeast estrogen screen on HPTLC or 96-well plates
      A. J. BERGMANN*, E. SIMON, A. SCHIFFERLI, A. SCHOENBORN, E. VERMEIRSSEN (*Swiss Centre for Applied Ecotoxicology, Eawag, Überlandstrasse 133, 8600 Dübendorf, Switzerland,

      Anal. Bioanal. Chem. 412, 4527-4536 (2020). HPTLC of 20 chemicals representative of migrants from plastic food contact materials on silica gel with chloroform - acetone - petroleum ether 11:5:5. Yeast estrogen screen was performed by spraying with yeast culture, followed by incubation at 30 ºC for 3 h. Detection by spraying with the indicator (2 mL 0.5 mg/mL 4-methylumbelliferyl-β-D-galactopyranoside-MUG in lacZ buffer), followed by incubation at 37 ºC for 20 min. Qualitative identification under UV light at 366 and 550 nm. The method was more sensitive than a microtiter plate YES (lyticase-YES). 

      Classification: 5b, 7
      127 005
      Utilization of a crown ether/amine‐type rotaxane as a probe for the versatile detection of anions and acids by Thin‐Layer Chromatography.
      S. MIYAGAWA, M. KIMURA, S. KAGAMI, T. KAWASAKI, Y. TOKUNAGA* (*Department of Materials Science and Engineering, University of Fukui, Bunkyo, Fukui, Japan;

      Chem. Asian J. 15(19), 3044-3049 (2020). The studied rotaxane combines a dibenzocrown of 8 ethers (DB24C8) with an axle chain (Ax) containing two amines, one of them in an aniline group, allowing stability of the rotaxane even when the other one is unprotonated. TLC on silica gel in 4 steps, with detection under UV light or after derivatization with phosphomolybdic acid in ethanol. (1) Before the synthesis of the rotaxane, unprotonated Ax was isolated by preparative TLC of the protonated Ax obtained by addition of HCl or toluenesulfonic acid (TsOH); the mobile phases were chloroform – methanol 10:1 and toluene – tetrahydrofurane 3:2, respectively. The isolated molecules were confirmed as totally unprotonated Ax by NMR, suggesting a complete loss of HCl and TsOH on the silica gel layer. (2) After synthesis, unprotonated rotaxane, pure vs. monoprotonated by the addition of 10 different acids (and purified by column chromatography CC), was applied on TLC plates and developed with dichloromethane – acetone – water 3:16:1; the hRF values were very different, depending on the counter-anions from the used acids. (3) The same behavior (except with sulfuric acid) was observed under the same conditions when CC was omitted (unprotonated rotaxane samples were mixed with each of the acids, or with two acids at the same time for acid-competitive TLC analysis). (4) When unprotonated rotaxane was applied under the same conditions as in step (3) with the sodium salts instead of the acids, the behavior was similar (except for the shapes of the spots, due to the salts in excess). The rotaxane can thus be used for the TLC separation and detection of sodium salts, by forming salts of protonated rotaxane with the anion afforded by these sodium salts. The rotaxane protonation seems to be promoted by the methanol of the spotting mixture; indeed, when step (3) was performed with the mobile phase chloroform – methanol 10:1, a second zone appeared because methanol formed a salt with the rotaxane (identified by NMR).

      Classification: 4e, 5a, 5b, 17a
      124 055
      Direct bioautography hyphenated to direct analysis in real time mass spectrometry: Chromatographic separation, bioassay and mass spectra, all in the same sample run
      T.T. HÄBE, M. JAMSHIDI-AIDJI, J. MACHO, Gertrud E. MORLOCK* (*Chair of Food Science, Institute of Nutritional Science, Interdisciplinary Research Center (IFZ), Justus Liebig Univ. Giessen, Heinrich-Buff-Ring 26-32, 35392, Giessen, Germany,

      J. of Chromatogr. A 1568, 188-196 (2018). Mass spectra by DART-MS were recorded directly in situ the bioautogram, immediately after direct bioautography (DB). This allowed to detect bioactive analytes within the bioautogram and discriminate microorganism cells and polar bioassay medium ingredients which could otherwise stress the MS system. DB-DART-MS was used for bioactive compounds in cosmetics using the Bacillus subtilis and Aliivibrio fischeri bioassays for detection of Gram-positive and Gram-negative antimicrobials. Planar yeast estrogen screen was used for detection of estrogen-effective compounds. HPTLC-DART-MS of parabens in hand creams either on silica gel with petroleum ether - glacial acetic acid 20:3 or on RP-18W with methanol - water 1:1. Detection under UV 254 and 366 nm. Bioassay by immersing the neutralized chromatograms into the bacterial suspensions.

      Keywords: densitometry HPTLC
      Classification: 4e, 5b
      103 030
      The effect of a magnetic field on the retention of polyaromatic hydrocarbons in planar chromatography
      Irena MALINOWSKA*, M. STUDZINSKI, H. MALINOWSKI (*Faculty of Chemistry, Department of Planar Chromatography, M. Curie-Sklodowska University, M. Curie-Sklodowska Sq. 3, 20-031 Lublin, Poland;

      J. Planar Chromatogr. 21, 379-385 (2008). Magnetic fields can affect the retention and shape of the chromatographic bands of the solutes investigated. The effect depends on the type of mobile phase, the properties of the adsorbent layer and the mode of development of the chromatogram (development distance). TLC and HPTLC of diphenyl, pyrene, benzo[a]pyrene, phenanthrene, fluoranthene, and chrysene on silica gel with n-hexane, n-octane, carbon tetrachloride, cyclohexane, benzene, and toluene, and n-hexane - benzene and n-hexane - toluene binary mobile phases. Evaluation under UV light.

      Classification: 5b
      57 027
      Gravity flow circular TLC (GFC/TLC)

      J. High Resol. Chromatogr. 8, 265-266 (1985). Description of gravity flow circular TLC for preparative separations by which the polycyclic aromatic hydrocarbon fraction of a creosote extract is isolated. A 200 Ál concentrated extract spotted at the center of the plate positioned 1 cm beneath the stem of a separation funnel. The spot was eluted with hexane, and the PAH-band focused with benzene. Detection under UV light.Polycyclic aromatic hydrocarbons, preparative TLC.

      Classification: 3d, 5b
      64 027
      Tetraprenyltoluquinol derivatives from the brown alga Cystoseira zosteroides
      V. AMICO*, P. NERI, G. ORIENTE, M. PIATTELLI, (*Dipartimento di Scienze Chimiche dell’Universita di Catania, 95125 Catania, Italy)

      Phytochemistry 28, 215-219 (1989). TLC on silica with dichloromethane - butanol 19:1. Detection by spraying with 10% solution of Ce(SO4)2 in 1M sulfuric acid and under UV 254 nm.

      Classification: 5b
      70 159
      Determination of aromatic hydrocarbons and their metabolites in human blood and urine
      J. ANGERER, B. HÖRSCH, (Inst. Arbeits- und Sozialmed. und Poliklinik für Berufskrankheiten, Univ. Erlangen-Nürnberg, Schillerstrasse 25, D-W-8520 Erlangen, Germany)

      J. Chromatogr. 580, 229-255 (1992). Discussion of the methods for the biological monitoring of aromatic hydrocarbons and their metabolites in human blood and urine by TLC, GC and HPLC.

      Classification: 5b, 32f
      79 052
      Thin-layer chromatography of C60 and C70 fullerenes
      L.S. LITVINOVA*, V.N. ZGONNIK, (*Inst. of Macromolecular Compounds of Russian Acad. of Sci., Bolshoi pr. 31, 199004 St. Petersburg, Russia)

      J. Planar Chromatogr. 10, 38-43 (1997). Under TLC conditions a mixture of C60 and C70 fullerenes can be separated on NH2, RP-18 and diol plates and on neutral and basic alumina by use of such eluents as hexane and i-octane and their mixtures with xylene or 1,2-dichlorobenzene. Chamber saturation has a negative influence on the separation. The separation of C60 and C70 fullerenes on silica, however, is achieved by developing the plate with hexane containing 5% pyridine (or iso-octane - pyridine 95:5) in a saturated chamber. The quantity of substance in the starting spot should not exceed 0.4 - 0.5 µg. Detection by densitometry at 254 and 366 nm.

      Classification: 5b