Part 3. Identification of drugs and their metabolites by PCA of standardized TLC data. J. Planar Chromatogr. 7, 233-241, (1994). Principal components analysis of standardized Rf values of 443 drugs and their metabolites chromatographed with four eluent systems provided a two-component model accounting for 70.8% of the total variance. The "scores" plot enabled either identification, or restriction of the range of inquiry to few candidates. This simple, cheap and fast analytical method is of vital importance in the identification of an unknown drug in cases of overdose intoxication or poisoning, and is particularly valuable in the unaided search for drugs and their metabolites in instances when the substance is very polar and cannot be identified by gas chromatography.

Proc. 9th Internat. Symp. Instr. Chromatogr., Interlaken, April 9.-11., 155-159 (1997). HPTLC of D/L- methadone and L-methadone on diol with toluene - hexane - diethylamine 3:6:1. Detection by derivatization with modified Dragendorff reagent; quantification by densitometry at 254 nm.

J. Chromatogr. B 751 (1), 19-27 (2001). TLC on silica gel with hexane - toluene - diethylamine 13:4:1. Quantitation by densitometry at 234 nm. Evaluation of the accuracy, precision, detection and quantitation limits of the methods by comparison with HPLC.

J. Ethnopharmacol. 158, 454-457 (2014). The authors described how the European Pharmacopoeia provides a legal and scientific reference for the quality control of medicines. The document highlighted HPTLC as a tool for the screening of herbal drugs containing certain contaminants, such as aristolochic acids._x000D_

(Biological-physiological procedures of detection in thin-layer-chromatography procedures after manual transfer.) GIT-Suppl. 3, 79-87 (1986). Survey of indirect detection methods using bio-detectors, which are often more sensitive than known chemical reactions. Application for the detection of substances with antibiotics activity. Active plant hormones, pesticides, mycotoxins and compounds with cytostatic activity. Useful technique: Place developed plate on agar or gelatine sheet containing the antibiotic allyactive compound.

Proc. 6th Int. Symp. Instrum. Planar Chromatogr., (Interlaken 1991), Inst. Chromatogr., Bad Dürkheim, FRG, 341-351 (1991). Screening techniques for 1,4-benzodiazepines, opiates and urea pesticides are presented as well as a literature review about forensic analysis with 18 references.

J. Chromatogr. 674, 3-13 (1994). Discussion of the potential and the constraints of TLC, GC and HPLC towards substance identification, together with their detection modes, including color reactions on the plate, MS and diode - array UV spectrophotometry. Evaluation of the identification power of TLC and color reactions plus GC or HPLC retention indices for the purpose. The possibility for identification by means of computerized database searches are considered.

J. Planar Chromatogr. 10, 208-216 (1997). TLC of ionic associates of BZ, phencyclidine, LSD, morphine, codeine, ethylmorphine, scopolamine, physostigmine, cocaine, ephedrine on silica and alumina with 68 alkaline mobile phases. Ionic associates of the basic organics were formed with bromoxylenol blue, cresol red, and eriochromecyanine-R.