Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
  • Browse and search by CBS classification: Select one of the 38 CBS classification categories where you want to search by a keyword
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Registered users can create a tailor made PDF of selected articles throughout CCBS search – simply use the cart icon on the right hand of each abstract to create your individual selection of abstracts. You can export your saved items to PDF by clicking the download icon.

      67 043
      Thin-layer chromatography - mass spectrometry
      I.D. WILSON*, W. MORDEN, (*ICI Pharmaceuticals Mereside Alderley Park Macclesfield, Cheshire, UK,)

      Proc. 6th Int. Symp. Instrum. Planar Chromatogr., (Interlaken 1991), Inst. Chromatogr., Bad Dürkheim, FRG, 401-408 (1991). Preliminary results are described for the combination of off-line TLC-FAB-MS for polar, ionisable compounds and their conjugated metabolites. HPTLC of benzoic acid, hippuric acid, phenolphthalein and its gucuronide, nitrophenol and its glucuronide and paracetamol and its sulfate on silica with chloroform - ethanol 3:2. Separated substances were removed and determinated by FAB-MS and MS-MS.

      Classification: 4e, 32b, 32f
      76 185
      Identification of efonidipine hydrochloride metabolites in rats
      H. Nakabeppu, A. Nakajima, Y Kamikawaji, Y Shinozaki, (Shiraoka Res. Station of Biological Science, Nissan Chemical Industries, Ltd., Saitama, Japan)

      Arzneim.-Forsch./Drug Res. 45, 766-770 (1995). TLC of efonidipine hydrochloride (2-benzyl(phenyl)amino)ethyl 1,4-dihydro-2,6-dimethyl-5-(5,5-dimethyl-2-oxo-1,3,2-dioxaphosphorinan-2-yl)-4-(3-nitrophenyl)-3-pyridinecarboxylate hydrochloride ethanol) and metabolites on silica with chloroform - methanol - diethylamine 18:1:1 or chloroform - methanol 1:1. Detection under UV 254 nm.

      Classification: 32b
      82 116
      Isolation and identification of metabolites of 3H- and 14C-deramciclane by OPLC-digital autoradiography on-line sample collection and mass spectrometry
      I. KLEBOVICH*, E. MINCSOVICS, J. SZUNYOG, K. LUDANYI, T. KARANCSI, K. /JSZASZY, B.D. KISS, K. VEKEY, (Dept. of Pharm., EGIS Pharmaceuticals Co. Ltd., H-1106 Budapest, Keresztúri út 30 - 38, Hungary)

      J. Planar Chromatogr. 11, 394-399 (1998). A new simple and powerful technique, on-line sample collection after high-resolution step-wise gradient OPLC separation combined with digital autoradiography (DAR) has been used for isolation of plasma and urine metabolites of 3H- or 14C-radiolabeled deramciclane (a new anxiolytic compound). This highly efficient separation can be followed by different MS techniques (FAB-MS, FAB-MS-MS, HPLC-MS, and HPLC-MS-MS) for determination of the structures of minor and major metabolites in different biological matrices. The combination of these methods resulted in a simple, sensitive, and efficient technique for metabolite research. OPLC on HPTLC silica gel, prewashed with methanol - water 4:1 with A) chloroform - acetonitrile 3:2 and B) n-butanol - acetic acid - water 4:1:1 for the gradient. Detection by digital autoradiography.

      Keywords:
      Classification: 32b
      121 088
      Development of quantitative HPTLC-densitometry methods following a model approach for transfer of TLC screening methods for pharmaceutical products of atenolol, chloramphenicol, furosemide, glibenclamide, penicillin V potassium, and praziquantel
      B. ZENG, K. NGUYEN, J. SHERMA* (*Department of Chemistry, 326 Hugel Science Center, Lafayette College, 701 Sullivan Road, Easton, PA 18042, USA, shermaj@lafayette.edu)

      J. Liq. Chromatogr. Relat. Technol. 41, 324-328 (2018). TLC minilab protocols were transferred to HPTLC validated methods for the determination of atenolol (1), chloramphenicol (2), furosemide (3), glibenclamide (4), penicillin V potassium (5), and praziquantel (6) on silica gel with methanol – ammonia 100:1 for (1), ethyl acetate – toluene – methanol 15:5:3 for (2), toluene – ethyl acetate – acetic acid 17:13:1 for (3), ethyl acetate – methanol – toluene – ammonia 11:7:1:1 for (4), ethyl acetate – methanol – acetic acid 20:10:1 for (5) and acetone – toluene 14:7 for (6). Qualitative evaluation under UV 254 nm. The hRf values for (1) to (6) were 35, 52, 30, 61, 48 and 65, respectively.

      Classification: 32b
      59 059
      Metabolism of the synthetic prostaglandin alfaprostol in the cow
      M. KAYKATY, G. WEISS, M. BARBALAS

      J. Agric. Food Chem. 34, 688-694 (1986). Determination of alfaprostol and metabolites on silica with benzene - dioxane - acetic acid 20:20:1. Detection by spraying with phosphomolybdic acid and heating. Detection of radioactive zones with a radiochromatogram spark chamber.

      Classification: 11b, 32b
      64 257
      Thin-layer chromatographic study of the metabolites of erythromycins in the vistar rat
      I.O. KIBWAGE, E. ROETS, A. VERBRUGGEN, J. HOOGMARTENS*, H. VANDERHAEGHE, (*Katholieke Univ. Leuven Lab. Farm. Chem., Inst. Farm. Wetenschappen, Van Evenstraat 4, B-3000 Leuven, Belgium)

      J. Chromatogr. 434, 177-186 (1988). TLC of metabolites of erythromycins on silica with three different solvent systems. Detection by spraying with 4-methoxy-benzaldehyde - sulfuric acid - ethanol 1:1:9 and heating at 110°C for 1 min. Confirmation by MS after TLC identification and purification.

      Classification: 32b
      67 188
      Increase of thiopental concentration in tissues of the rat due to an anestesie with halothane
      U. BÜCH, P. ALTMAYER, J. C. ISENBERG, H.P. BÜCH, (Clinic of Anesthesiology and Intens. Care Med., Univ. of the Saarland, Homburg, FRG)

      Arzneim.-Forsch./Drug Res. 41, 363-366 (1991). TLC of thiopental (after prechromatography) with benzene - tissue components running in the front, thiopental remaining at the start - on silica with toluene - acetone diethylamine 80:19:1. Quantification after elution with 0.1 N NaOH using UV at 305 nm.

      Classification: 24, 32b
      76 186
      Detection and determination of total amlodipine by high-performance thin-layer chromatography
      K.K. PANDYA, M. SATIA, T.P. GANDHI, I.A. MODI, R.I. MODI, B.K. CHAKRAVARTHY*, (*Dept. Phytochem., Cadila Labs. Ltd., 244 Ghodasar, Ahmedabad 380050, India)

      J. Chromatogr. B 667, 315-320 (1995). TLC on silica with 1) chloroform, 2) chloroform - methanol - acetic acid 150:25:4. Detection under 365 nm. Quantification by densitometry at 365 nm (fluorescence).

      Classification: 32b