Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
  • Browse and search by CBS classification: Select one of the 38 CBS classification categories where you want to search by a keyword
  • Keyword register: select an initial character and browse associated keywords
  • Search by CBS edition: Select a CBS edition and find all related publications

Registered users can create a tailor made PDF of selected articles throughout CCBS search – simply use the cart icon on the right hand of each abstract to create your individual selection of abstracts. You can export your saved items to PDF by clicking the download icon.

      73 132
      Absorption, distribution, metabolism and excretion of (14C)Ebastine after a single administration in rats
      T. FUJII, S. MATSUMOTO, H. AMEJIMA, T. HATOYAMA, M. NAKAO, A. KAGEMOTO, K. TANAKA, H. MIYAZAKI, (Developm. Res. Lab., Dainippon Pharm. Co. Ltd., Osaka, Japan)

      Arzneim.-Forschung / Drug Res. 44, 527-538 (1994). TLC of ebastine (4'-tert-butyl-4-(4-(diphenylmethoxy)piperidino)butyrophenone), carebastine and metabolites on silica with chloroform - methanol - ethyl acetate - acetic acid 78:10:10:2. Radio scanning.

      Classification: 32b
      80 023
      TLC-DAR for the analysis of biological samples
      I. KLEBOVICH*, J. SZUNYOG, I. HAZAI, (*EGIS Pharmaceuticals Ltd, Dept. of Pharmacokinetics, P.O. Box 100, H-1475 Budapest, Hungary)

      A newly developed rapid tool for studying drug metabolism. J. Planar Chromatogr. 10, 399-405 (1997). Comparison of advantages and disadvantages of combined thin-layer chromatography - digital autoradiography (TLC-DAR) and other techniques used for plate evaluation in planar chromatography. It is demonstrated that this newly developed method can be widely used for the analysis of a variety of biological samples and, because information is obtained quickly at low cost, it is an excellent tool in metabolism research. DAR is a convenient and extremely rapid means of locating and quantifying radioactive metabolites on the TLC plate after separation and/or purification. Example used: TLC on silica of deramciclane (a new anxiolytic compound) and metabolites with butanol - acetic acid - water 4:1:1.

      Keywords:
      Classification: 4e, 32b
      89 154
      Plasma analysis of celiprolol by HPTLC
      H.S. SAVALE, K.K. PANDYA, T.P. GANDHI, I.A. MODI, R.I. MODI, M.C. SATIA*, (*Cadila Pharm. Ltd., R&D Unit, 1389, Trasad Rd, Dholka, Ahmedabad-387 810, India)

      JAOAC Int. 84, 1252-1257 (2001). Analytical TLC of celiprolol (3-{3-acetyl-4-[3-(tert-butylamino)-2-hydroxypropoxy]phenyl}-1,1-diethyl urea) on silica gel with ethyl acetate - methanol - strong NH3 17:2:1. Detection and quantification at 243 nm. Detection limit was 10 ng/mL.

      Keywords:
      Classification: 32b
      58 152
      Pharmacokinetics of 3H-pipethiaden after single oral and intravenous administration in rats
      R. LAPKA, Z. FRANC, S. SMOLIK

      Drug. Res. 35, 486-488 (1985). TLC of pipethiaden (4-(1-methyl-4-piperidylidene)-4,9-dihydrothieno-(2,3-c)-2-benzothiepine) on silica with chloroform - methanol - NH3 90:10:1 and dichloroethane - methanol - NH3 60:40:1. Detection by UV 254 nm. Autoradiography. Radioactive spots were scraped out and measured by liquid scintillation counting.

      Classification: 32b
      62 210
      Untersuchung zur Biotransformation von Meclozin im menschlichen Körper
      S. GOENECHEA, G. RÜCKER, H. BRZEZINKA, G. HOFFMANN, M. NEUGEBAUER, G. GLANZMANN, (Inst. f. Rechtsmedizin, Univ. Bonn, D-5300 Bonn, FRG)

      - Investigation of the biotransformation of Meclozin in the human body. J. Clin. Chem. Clin. Biochem. 26, 105-115, (1988). Analytical and preparative TLC of Meclozin (1-(4-chlorophenyl)-phenylmethyl-4-(3-methylphenyl)-methyl-piperazine) and metabolites on silica with 6 different eluents (e.g. toluene - ethanol - acetic acid 60:5: 35; methanol - NH3 (25%) 100:1. Detection with potassium iodoplatinate, 2,6-dichloro- quinonechlorimide, Altmann-reagent or bromocresol green-bromophenol-blue-potassium permanganate reagent. Quantification via GC after elution.

      Classification: 32b
      66 146
      Microsomal oxidation of praziquantel
      A. HÖGEMANN, K. KIEC-KONONOWICZ, F. WESTHOFF, G. BLASCHKE, (Inst. für Pharmaz. Chemie der Univ. Münster, Münster, Germany)

      Arzneim.-Forsch. 40, 1159-1162 (1990). TLC of praziquantel and metabolites on silica with butanol – chloroform – ethyl acetate – NH3 20:20:60:3, methanol – dichloromethane 1:1. Determination with linear TLC radioactivity scanner response UV.

      Classification: 32b
      73 138
      Residue depletion studies on danofloxacin in the chicken
      M.J. LYNEK et al. (10 authors), (Drug Metabolism Dept., Central Res. Div., Pfizer, Groton, Conn. 06340, USA)

      J. Agric. Food. Chem. 42, 289-284 (1994). TLC of (3H)-1'-danofloxacin mesylate on silica with chloroform - methanol 85:15 and ethyl acetate - MEK - formic acid - water 3:3:1:1. Detection under UV 366 nm.

      Classification: 32b
      80 096
      HPTLC determination of isoniazid and acetylisoniazid in serum
      D. HABEL, S. GUERMOUCHE, M. H. GUERMOUCHE*, (Inst. de Chimie, USTHB, B. P. 32, El-Alia, Bab-Ezzouar, Alger, Algeria)

      Comparison with HPLC. J. Planar Chromatogr. 10, 453-456 (1997). HPTLC on silica with ethyl acetate - methanol 7:3. Quantification by densitometry at 254 nm. The method described has proved useful for the analysis of isoniazid (INH) and its serum metabolite acetylisoniazid (AcINH) in the concentration range 0.5 to 10 mg/L. The precision and accuracy of the method are comparable with those of the HPLC method. The HPTLC assay is more attractive because of its speed (approx. 30 min for 10 samples) and simplicity. It can be used for routine analysis in clinical laboratories for precise quantification of INH serum concentrations or determination of acetylator phenotype from the measured ratio AcINH:INH.

      Keywords:
      Classification: 32b