Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
  • Browse and search by CBS classification: Select one of the 38 CBS classification categories where you want to search by a keyword
  • Keyword register: select an initial character and browse associated keywords
  • Search by CBS edition: Select a CBS edition and find all related publications

Registered users can create a tailor made PDF of selected articles throughout CCBS search – simply use the cart icon on the right hand of each abstract to create your individual selection of abstracts. You can export your saved items to PDF by clicking the download icon.

      115 061
      Comparative study of reversed-phase high-performance liquid chromatography versus thin-layer chromatography-densitometry for determination of citicoline sodium in presence of its alkaline degradation products
      Omnia A. MAHMOUD*, Maha A. HEGAZY, H. SALEM, Azza A. MOUSTAFA (*Analytical Chemistry Department, Faculty of Pharmacy, October University for Modern Sciences and Arts (MSA), 11787 6th October City, Egypt, dr.omniali@gmail.com)

      J. Planar Chromatogr. 28, 241-247 (2015). TLC of (1) citicoline sodium in the presence of its (2) alkaline degradation products in pharmaceutical oral solution on silica gel with ammonia - ethyl acetate - triethylamine 12:7:1. Quantitative determination by absorbance measurement at 272 nm. The hRF value was 35 for (1) and 10 for (2). Linearity for (1) was between 0.6 and 2.2 µg/zone. The intraday precision was 0.2 % and interday precision was 1.2 % for (1). The LOD and LOD of (1) were 41 ng/zone and 237 ng/zone, respectively.

      Classification: 2f, 32b
      58 171
      Biochemische Untersuchungen mit Oxitropiumbromid
      D. WAHL, R.G.A. VAN WAYJEN, A.A. VAN DEN ENDE

      2. Pharmakokinetik und Metabolismus im Menschen. (Biochemical studies with oxitropium bromide. 2. Pharmacokinetics and metabolism in man.) Drug Res. 35, 266-272 (1985). TLC of oxitropium bromide (18 )-6,7-epoxy-8-ethyl-3-(L-)-tropoloxyl)-1H,5H-tropanium bromide) and metabolites on silica with ethyl acetate - formic acid - water 4:1:1, acetonitrile - chloroform - formic acid - water 75:40:10:10 and MEK - acetic acid - water 6:2:2. Quantification by radioautography.

      Classification: 32b
      64 179
      Determination of potential degradation products of piroxicam by HPTLC densitometry and HPLC
      H. TOMANKOVA*, J. SABARTOVA, (*State Inst. for Drug Cont., Srobarova 48, P.O.Box 87, 10041 Prague, Czechoslovakia)

      Chromatographia 28, 197-202 (1989). HPTLC of 2-aminopyridine, DP-I and DP-II on silica with ethyl acetate - toluene - diethylamine - 10:10:5 and toluene - ethanol - acetic acid 8:1.2:0.5. Quantification by densitometry at 296 nm in the concentration range of 600 - 1200 ng 2-aminopyridine/spot and 300 - 600 ng DP-I and DP-II/spot.

      Classification: 21, 32b
      66 167
      Study of metabolism of p-bromomethamphetamine in rat
      E. SZÖKO*, H. KALASZ, A. GYÖRGY, J. KNOLL, K. MAGYAR, (*SOTE, Inst. Pharm., Budapest, Nagyvarad tér 4, Hungary)

      (Hungarian). Acta Pharmaceutica Hungarica 59, 63-68 (1989). TLC on silica with chloroform – triethanolamine 95:5. Detection under UV or by spraying with ninhydrin.

      Classification: 32b
      76 158
      Binding of anticancer drugs to human serum albumin studied by reversed-phase chromatography
      E. FORGACS*, T. CSERHATI, (*Central Res. Inst. for Chem., Hungarian Acad. of Sci., P.O. Box 17, H-1525 Budapest, Hungary)

      J. Chromatogr. 696, 265-272 (1995). Study of the interaction of eight commercial anticancer drugs with human serum albumin (HSA) by charge-transfer reversed-phase TLC in neutral, acidic, basic and ionic environments. Calculation of the relative strength of interaction. Discussion of the effect of the pH and the presence of mono- and divalent cations on the strength of anticancer drugs to interact with HSA on their molecular structure, and of the impact of the steric parameters of anticancer drugs on their capacity to bind to HSA. Discussion also, of electronic parameters on the HSA-drug interaction.

      Classification: 32b
      82 108
      Metabolism of 2(R,S)-1,2-bis(nicotinamido)propane, a new agent with anti-vasospasm activity, in rats and rabbits
      M. ISHIGAI, Y. ISHITANI, Y. ORIKASA, H. KAMIYAMA, K. KUMAKI, (Drug Metabolism and Pharmacokinetics Laboratory, Chugai Pharmaceutical Co. Ltd., Tokyo, Japan)

      Arzneim. Forsch./Drug Res. 48, 429-435 (1998). TLC of 14C-AVS, metabolites and determination of the radiochemical purity on silica gel with chloroform - methanol 5:1 and chloroform - methanol (ammonia saturated) 2:1.

      Keywords:
      Classification: 32b
      99 151
      Monitoring of in vitro fat digestion by electron paramagnetic resonance spectroscopy
      A. RUEBE, S. KLEIN, K. MAEDER* (*Department of Pharmacy, Institute of Pharmaceutics and Biopharmaceutics, Martin Luther University Halle-Wittenberg, Halle/Saale, Germany, maeder@pharmazie.uni-halle.de)

      Pharm. Res. 23, 2024-2029 (2006). HPTLC of the chloroform extract of a lipophilic model drug (tempol benzoate) into a long-chain triacylglyceride (olive oil) after 0, 5, 20 and 45 min of digestion with pancreatin on silica gel, by AMD using an 11 step gradient based on hexane and ethyl acetate. Detection by spraying with an aqueous copper sulfate solution (10 % copper sulfate, 8 % phosphoric acid, 5 % methanol), followed by heating at 150 °C. Quantitative determination by absorbance measurement at 675 nm. Lipid recovery was between 104 and 119 %.

      Classification: 32b
      119 106
      TLC bioautographic method for activity screening of natural acetyl cholinesterase inhibitors obtained from Xinjiang Mohe tobacco
      J. WANG (Wang Jian), P. ZHU (Zhu Pingping), G. NI (Ni Guozhu), L. WEN (Wen Linyu), L. ZHI (Zhi Ling), SH. HU (Hu Shuchen)* (*Xinjiang Med. Univ., Xinjiang, Wulumuqi 830011, China, ansenl224@163.com)

      J. of China Pharm. 23 (20), 38-40 (2014). Nicotine is a toxic substance in tobacco. Studies have shown that nicotine may prevent and treat Alzheimer's disease (AD) and Parkinson's syndrome (PD). At present, the most effective method to treat AD is by inhibiting the activity of acetylcholinesterase (AChE), thus enhancing the cholinergic activity indirectly. In order to clarify the mechanism of nicotine reducing the incidence of AD, the activity of natural AChE inhibitors in Xinjiang Mohe tobacco was screened by TLC on silica gel with (A) ethyl acetate – methanol – ammonium hydroxide 70:30:1, followed by detection via enzyme inhibition (this is not bioautography, as stated in the title): firstly by spraying with 1.0 U/mL AChE (AChE 500 U + tris-HCl buffer solution of pH 7.8 500 mL + bovine serum albumin 500 mg), followed with 1.5 g/L alpha-naphthyl acetate (150 mg in ethanol 40 mL + water 60 mL) and then with 0.5 g/L Fast blue B salt, resulting in white zones on purple background; (B) toluene – ethyl acetate - diethylamine 7:2:1, detection by spraying with 0.2 mmol/L 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical reagent, resulting in white to yellow zones on pale purple background. The results indicated that nicotine in Xinjiang Mohe tobacco could bind to AChE and thus inhibit its activity.

      Classification: 32b, 32e