Chinese J. Chem. 14, 354-358 (1996). Presentation of a computer-assisted method for optimization of mobile phase composition and development distance in gradient two-step development HPTLC. The method is based on a system which can predict the final Rf values for gradient two-step development from values measured using five preliminary runs. The statistical scanning method is then used for optimization, using Rf difference as the selection criterion. The method was evaluated using a mixture of eight components and showed excellent agreement between predicted and experimental results.

J. Planar Chromatogr. 13, 337-347 (2000). HPTLC on cyano phases with five binary and ten ternary mobile phases containing methanol, acetonitrile, and water. A retention model was formulated at each composition using the solvation-parameter model. A mixture-design approach was then used to model the individual system constants as a continuous function of mobile phase composition, producing system surfaces from which retention surfaces could be calculated for method development. Regression analysis for the full data set indicated that the mixture-design models can be used to estimate solute migration properties with accuracy similar to that of the original solvation-parameter models.

Trends Anal. Chem. 81, 51-62 (2016). Review on aspects to consider during calibration for quantitative chromatographic analysis such as noise and detector response, data acquisition and processing, calibration curve and inverse calibration.

Determination of isoniazid in serum by thin-layer chromatography.) (Chinese). J. Pharm. Anal. (Yaowu Fenxi Zazhi) 17, 116-118 (1997). TLC on silica with chloroform - methanol 9:1. In situ spectra recording of isoniazid and its salicylaldehyde - and benzaldehyde-derivatives. Quantification by densitometry at 225 nm. Validation of the method by investigation of linearity and range, RSD, recovery and detection limits for the compounds.

Acta Chromatographica 21(3), 369-378 (2009). Determination of the lipophilicity RM0 and log PTLC of thirteen novel, potentially biologically active, 12 H-quino[3,4- b ] [1,4] benzothiazinium salts by TLC on RP-18 with methanol – aqueous Tris buffer mixtures. RM values were linearly dependent on methanol concentration, and extrapolation of these to 0% methanol gave the lipophilicity RM0. log PTLC was obtained from RM0 by use of a calibration curve obtained for five standards of known experimental lipophilicity (log P). The lipophilicity log Pcalcd was calculated for the thirteen quinobenzothiazines by use of nine software products. The chromatographic lipophilicity RM0 can be used as a measure of the lipophilicity of the azaphenothiazine derivatives investigated.

J. Chromatogr. 252, 193-208 (1983). Investigation on the chromatographic properties of 132 compounds on two ion-pair systems on reversed-phase thin-layer plates.

Determination of parameters characterizing TLC systems. J.Liquid Chromatogr. 6, 81-93 (1983). Discussion of an equation, derived in terms of the thermodynamic formulation of TLC with mixed mobile phase. The parameters of this equation, describing solute-solvent interactions in thermolabile phase and phase-exchange equilibrium between molecules of both solvents are determined by using its linear forms. These linear relationships have been examined by applying the TLC data for eight different binary mobile phases.

J. Xiangtan Univ. 1, 77-80 (1987) (Xiangtan Daxue Ziran Kexue Xuebao). TLC on primary amine N1923-silica with sulfuric acid. The plot of log (1/Rf-1) against the atom numbers of the rare earths divides the rare earths into 4 groups following the order of atom number: La-Nd, Pm-Gd, Gd-Ho and Ho-Lu.