A newly developed rapid tool for studying drug metabolism. J. Planar Chromatogr. 10, 399-405 (1997). Comparison of advantages and disadvantages of combined thin-layer chromatography - digital autoradiography (TLC-DAR) and other techniques used for plate evaluation in planar chromatography. It is demonstrated that this newly developed method can be widely used for the analysis of a variety of biological samples and, because information is obtained quickly at low cost, it is an excellent tool in metabolism research. DAR is a convenient and extremely rapid means of locating and quantifying radioactive metabolites on the TLC plate after separation and/or purification. Example used: TLC on silica of deramciclane (a new anxiolytic compound) and metabolites with butanol - acetic acid - water 4:1:1.

J. Chromatogr. A 774, 313-377 (1997). TLC of 9 inorganic anions and 11 metal ions on cellulose, silica and their mixtures with mixed solvent systems containing 0.1 M NH4OH and acetone. Detection by spraying with 7 reagents. Discussion of the retention behavior. Quantitation of SCN- by spectrophotometry at 460 nm, using acidic FeCl3 solution as chromogenic reagent. Use of the proposed TLC - colorimetric method to fortified samples of the title matrices.

Anal Chem. 70, 1916-1920 (1998). The combination of TLC with X-ray fluorescence without any interface enables the direct, nondestructive visualization of elements separated on a TLC plate. In addition to inorganic compounds, organics like phenolic compounds containing chlorine, bromine, or iodine were distinctly detected by individual elemental imaging. TLC of inorganic metal acetates and FeCl3 and MgCl2, protoporphyrin and the metal complexes (Mn and Co), chlorinated pesticide standards, pentachlorophenol, pentabromophenol, 2,4,6-triiodophenol on e.g. cellulose and silica gel with suitable solvent systems. After drying the plate was wrapped in polyethylene film and pasted on a sample stage of 100 x 100 mm2 using two-sided adhesive tape. XRF was conducted using an X-ray analytical microscope.

J. Planar Chromatogr. 15, 286-288 (2002). To characterize the stability and retention behavior of zinc carboxylato mixed-ligand complexes movement of the carboxylate ligand has been monitored by TLC coupled with time-of -flight secondary-ion mass spectrometry (TLC-TOF SIMS). TLC of zinc carboxylato mixed-ligand complexes on RP-18, prewashed with methanol, with methanol - water 2:3. After development the layers were coated with silver, from the vapor state, and the analytes were eluted with a strongly polar mobile phase to a target channel.

J. Planar Chromatogr. 18, 67-72 (2005). TLC of trans-resveratrol (trans-3,5-dihydroxystilbene), semicarbazide and dimedone (as standards) on silica gel using different mobile phases; OPLC on silica gel with chloroform - methanol 10:1. After drying bioautographic detection by immersion in the bacterial suspension of Pseudomonas savastanoi for 25 s. Visualization with MTT either after a short draining period or after overnight incubation.

Einführung in die quantitative DC: Grundlagen, Möglichkeiten, Automatisierung, Teil 7. (Introduction to quantitative thin-layer chromatography: basics, possibilities, automation, part 7). This section presents the principle procedures involved in positioning the TLC spots in the measuring aperture of a computer-controlled TLC photometer. The various measuring techniques such as double wavelength or double beam measurements using a computer-controlled TLC photometer are explained, and the high degree of flexibility of such systems is discussed (2 refs.).

J. Chromatogr. 552, 613-623 (1991). Demonstration of the advantages of storage of the effluent from a reverse-phase column LC separation on a TLC plate for the separation and identification of polycyclic aromatic hydrocarbons in a marine sediment sample. Deposition of the effluent from a microbore LC column on a linearly moving TLC plate through a spray jet assembly interface. Identification of 11 polycyclic aromatic hydrocarbons by measuring their fluorescence excitation and emission spectra on the TLC plate with a conventional spectrometer.

J. Chromatogr. 437, 328-332 (1988). Preparative separation of closely related alkaloids from Papaver and Fumaria species on aluminium oxide by centrifugal TLC with cyclohexane - toluene - diethylamine 320:80:1, 160:40:1 or 160:40:3. Flow-rate 0.5-1.5 mL/min. The rotors (1 mm layer thickness) were prepared from a mixture of 40 g basic aluminium oxide, 10g calcium sulfate hemihydrate and 110 mL water.