Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
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      92 107
      RPTLC determination of the lipophilicity of 1,2-benzisothiazol-3(2H)-one derivatives substituted in the heterocyclic ring
      T. SLAWIK*, B. PAW, (*Dept. of Med. Chem., Med. Univ. of Lublin, 6 Chodzki Street, 20-093 Lublin, Poland)

      J. Planar Chromatogr. 16, 442-446 (2003). TLC of 8 new substituted 1,2-benzisothiazol-3(2H)-one derivatives on RP-18 with methanol - water, methanol - pH 1.95 glycine buffer and methanol - pH 10.0 glycine buffer at 20°C. Visualization under UV 254 nm.

      Keywords:
      Classification: 32a
      94 051
      HPTLC method for guggulsterone - Quantitative determination of E- and Z-guggulsterone in herbal extract and pharmaceutical dosage form
      Himani AGARWAL, Neeraj KAUL, A. R. PARADKAR, K. R. MAHADIK (Department of Quality Assurance Techniques, Bharati Vidyapeeth Deemed University, Poona College of Pharmacy, Erandwane, Pune 411038, India)

      J. Pharm. Biomed. Anal. 36, 33-41 (2004). A sensitive selective, precise and robust HPTLC method for the analysis of E and Z stereoisomers of guggulsterone (the hypolipidemic agent in the gum-resin exudates of Commiphora mukul) both as a bulk drug and in formulations was developed and validated. Separation on silica gel with toluene - acetone 9:1. Quantitative determination by absorbance measurement at 250 nm. This system was found to give compact spots for E- and Z-guggulsterone (Rf value of 0.38 ± 0.02 and 0.46 ± 0.02 respectively) following double development with the same mobile phase. Both E- and Z-guggulsterone showed good linearity in the concentration range of 100-6000 ng/spot. The method was validated for precision, robustness, recovery, and specificity. The proposed HPTLC method is suitable for the identification and quantitation of these isomers in herbal extracts and pharmaceutical dosage forms.

      Classification: 32a
      94 085
      Comparison of HPTLC and HPLC for determination of econazole nitrate in topical dosage forms
      Gordana POPOVIC*, M. CAKAR, K. VUCICEVIC, S. VLADIMIROV, D. AGBABA (*Faculty of Pharmacy, University of Belgrade, Vojvode Stepe 450, P. O. Box 146, 11000 Belgrade, Serbia and Montenegro)

      J. Planar Chromatogr. 17, 109-112 (2004). HPTLC of econazole nitrate (1-[2-[4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole nitrate) on silica gel in a twin-trough chamber with n-butyl acetate - carbon tetrachloride - methanol - diethylamine 6:12:5:1. Quantitative determination by reflectance/absorbance measurement at 230 nm.

      Classification: 32a
      95 051
      The effect of the structure of mixed tetraoxanes on their chromatographic behavior on different adsorbents
      S. B. GAICA, D. M. OPSENICA, B. A. SOLAJA, Z. L. TESIC, Dusanka M. MILOJKOVIC-OPSENICA* (*Faculty of Chemistry, University of Belgrade, P. O. Box 158, 11001 Belgrade, Serbia and Montenegro)

      J. Planar Chromatogr. 17, 342-349 (2004). TLC of 29 1,2,3,4-tetraoxanes on silica gel, cyano phase, and RP-18. The binary mobile phases ethyl acetate - petroleum ether and ethyl acetate - toluene were used under normal-phase conditions, and water - organic modifier (methanol, acetone, dioxane) under reversed-phase conditions. Chromatography was performed using a HPTLC horizontal developing chamber equilibrated for 15 min with the vapor of the mobile phase. Detection by spraying with 50 % sulfuric acid and heating until the spots became visible.

      Classification: 32a
      95 083
      Estimation of ranitidine HCl and domperidone in combined dosage form using HPTLC
      M. S. CHARDE*, M. J. UMEKAR, S. B. JOSHI, A. V. KASTURE (*Department of Pharmaceutical Sciences, Nagpur University, Nagpur 440033, India)

      IPC 56th 2004, Abstract No. GP-8. Simultaneous HPTLC determination of ranitidine and domperidone on silica gel with methanol - 1, 4-dioxan 2:3. Quantitative determination by densitometric scanning at 282 nm. Rf values were 0.33 for ranitidine and 0.78 for domperidone. Linearity range was 0.5 – 2.5 mg/mL for both of the drugs. The recovery was in the range of 100.25 – 100.78 %. The method is suitable for the analysis of both drugs in combined dosage form.

      Classification: 32a
      96 079
      Study of the liquid chromatographic separation and determination of NSAID
      R. Bhushan*, S. Joshi, M. Arora, M. Gupta (*Department of Chemistry, Indian Institute of Technology Roorkee, Roorkee-247 667, India)

      J. Planar Chromatogr. 18, 164-166 (2005). TLC of non-steroidal anti-inflammatory drugs (NSAID), i.e. mefenamic acid, naproxen, ibuprofen, flurbiprofen, ketoprofen, paracetamol, and diclofenac, on silica gel with chloroform - methanol , chloroform - ethyl acetate, acetonitrile - methanol - water, acetonitril - methanol in different proportions. Detection with iodine vapor.

      Classification: 32a
      96 109
      Identification and quantitation of polymyxin B, framycetin, and dexamethasone in an ointment by using thin-layer chromatography with densitometry
      J. KRZEK*, A. MASLANKA, P. LIPNER (*Jagiellonian University, Collegium Medicum, Department of Inorganic and Analytical Chemistry, 9 Medyczna St, 30688 Cracow, Poland)

      J. AOAC Int. 88, 1549-1554 (2005). TLC of polymyxin B, framycetin, and dexamethasone on silica gel with methanol and methanol - n-butanol - 25 % ammonia - chloroform 14:4:9:12 for framycetin and polymyxin B. Quantitative determination by densitometry at 550 nm after detection with 0.3 % ninhydrin solution. Dexamethasone was separated with cyclohexane - ethyl acetate 2:3, quantitative determination by absorbance measurement at 245 nm. Similar accuracy, relative standard deviation values from 1.49 to 2.47 % and relative error values from 0.02 to 0.81 % are comparable to those obtained with the reference methods.

      Classification: 32a
      96 135
      Quantitative analysis of ethamsylate and mefenamic acid in tablets by use of planar chromatography
      Y. S. Jaiswal, G. S. Talele*, S. J. Surana (*Department of Pharmaceutical Chemistry, R. C. Patel College of Pharmacy, Karwand Naka, Shirpur Dhule 425405, Maharashtra, India)

      J. Planar Chromatogr. 18, 460-464 (2005). HPTLC of ethamsylate and mefenamic acid on silica gel prewashed with methanol, in a pre-saturated twin-trough chamber with chloroform - methanol - acetic acid 50:40:1. After drying at 50 °C for 5 min quantitative determination by absorbance measurement at 300 nm. The validated calibration range was 500-2500 ng/spot (r = 0.998) and 500-2500 ng/spot (r = 0.997) for ethamsylate and mefenamic acid, respectively.

      Classification: 32a