(Hungarian). Magyar Kémiai Folyoirat 102, 343-355 (1995). TLC of heterocondensed quinazdones on silica with benzene - methanol 4:1. Detection under UV 254 nm.

J. Planar Chromatogr. 10, 460-463 (1997). HPTLC of chlorpheniramine maleate, methscopolamine nitrate, pseudoephedrine hydrochloride, brompheniramine maleate, phenylpropanolamine hydrochloride, and guaifenesin on silica. PE, CM, and BM were developed to a distance of ca. 6 cm with 1-butanol - deionized water - acetic acid 7:2:1; plates containing PP were developed to a distance of ca. 6 cm with ethyl acetate - methanol - conc. NH3 17:2:1. All developments were performed at 20°C and 60% relative humidity with chamber saturation. Quantification by densitometry at 277 nm for PE, at 264 nm for CM, at 265 nm for BM, and at 209 nm for PP. It has been demonstrated that the new HPTLC method achieved recoveries as a percentage of tablet label values, standard deviations for replicate analyses and recoveries of spiked samples that compare very favorably with data reported on the HPLC analyses of drugs. Advantages of the method: Internal standards are not required, high sample throughput, very low solvent usage per sample, accuracy and precision are more than satisfactory for performing pharmaceutical analysis with validation according to GLP and GMP recommendations.

J. Planar Chromatogr. 11, 201-204 (1998). TLC of betamethasone valerate and clotrimazole on silica gel with chloroform - acetone - acetic acid 34:4:3. Quantitation by densitometry in absorbance-reflectance mode at 228 nm. The method has been found suitable for the routine analysis of cream and products of similar composition in pharmaceutical industry quality control laboratories.

J. AOAC Int. 82, 825-829 (1999). HPTLC of sulpiride, 2-aminomethyl-1-ethylpyrrolidine (impurity A) and methyl-5-sulphamoyl-2-methoxybenzoate (impurity B) on silica gel with dichloromethane - methanol - 25 % NH3 45:7:1. Densitometry in absorbance/reflectance mode at 240 nm for sulpiride and impurity B; after spraying with ninhydrin solution, heating at 80°C for 10 min scanning of impurity A was done at 240 nm and 500 nm. Simple, accurate, reproducible and quick TLC procedure.

Indian Drugs 36 (5), 293-295 (1999). HPTLC of metronidazole and norfloxacin on silica gel with chloroform - methanol - diethyl amine - water 450:100:2:1. Densitometry at 254 nm with tinidazole as internal standard. Recovery 98.0 to 101%.

J. Planar Chromatogr. 13, 296-300 (2000). TLC of cimetidine, famotidine, nizatidine, ranitidine hydrochloride on silica gel with ethyl acetate - acetone - water 5:4:1, ethyl acetate - methanol - conc. NH3 13:4:3; 21:2:2, ethyl acetate - methanol - toluene - conc. NH3 40:25:20:2 and ethyl acetate - isopropanol - conc. NH3 - water 25:15:4:1; 25:15:4:2. Detection under UV 254 nm and by exposure to iodine vapor; quantitation by densitometry.

J. Planar Chromatogr. 14, 291-295 (2001). TLC of 36 4-benzylthio derivatives of 2-pyridinecarbothioamide and 2-pyridinecarbonitrile on silanized silica gel (impregnation by overnight (15.5 h) development with diethyl ether - silicone oil 19:1) with phosphate buffer of pH 7.4 or 3.0 or 5% ammonia as aqueous component of the mobile phase and acetone or methanol as organic modifier. Visualization at 254 nm.

JAOAC Int. 84, 1296-1300 (2001). HPTLC of fludarabine (FDB), cytarabine (CTB), gemcitabine (GTB), and fluorouracil (5 FU) on silica gel with ethyl acetate - methanol - water 5:1:1. After development the plate is dried at 50°C on a TLC plate heater. Detection under UV 254 nm. Quantification by densitometry at 270 nm.