Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
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      114 089
      Simultaneous determination of atorvastatin calcium and olmesartan medoxomil in a pharmaceutical formulation by reversed phase high-performance liquid chromatography, high-performance thin-layer chromatography, and UV spectrophotometric methods
      Hiral SONI, Charmy KOTHARI*, D. KHATRI, Priti MEHTA (*Nirma University, Institute of Pharmacy, Pharmaceutical Analysis, Ahmedabad Gujarat 382 481, India, charmyshah@gmail.com)

      J. AOAC Int. 97, 791-797 (2014). HPTLC of (1) atorvastatin calcium and (2) olmesartan medoxomil on silica gel with chloroform – methanol – acetonitrile 2:1:2. Quantitative determination by absorbance measurement at 276 nm. The hRF values of (1) and (2) were 47 and 69, respectively. Linearity was between 300 and 750 ng/zone for (1), and between 600 and 1500 ng/zone for (2). The intermediate inter-day and intra-day precisions were below 1 % (n=9) for both, (1) and (2). The LOD and LOQ were 6.3 and 19.0 ng/zone for (1) and 3.1 and 9.5 ng/zone for (2). Recoveries for (1) and (2) were in the range of 98-102 %. The method showed comparable results to a validated HPLC method and a UV spectrophotometric method.

      Classification: 32a
      117 098
      Comprehensive study of the stability of cefepime hydrochloride and cefuroxime axetil under various environmental conditions
      Monika DABROWSKA*, M. STAREK, W. OPOKA (*Department of Inorganic and Analytical Chemistry, Faculty of Pharmacy, Collegium Medicum Jagiellonian University, 30-688 Kraków, Poland, mtylka@cm-uj.krakow.pl)

      J. Planar Chromatogr. 29, 264-272 (2016). HPTLC of cefepime hydrochloride (1) and cefuroxime axetil (2) on silica gel with ethanol – isopropanol – glacial acetic acid – water 4:4:1:3 for (1) and chloroform – ethyl acetate – glacial acetic acid – water 4:4:4:1 for (2). The hRF values for (1) and (2) were 21 and 93, respectively. The method was applied to study the photodecomposition of (1) and (2) in the absence and presence of selected metal ions during UV irradiation.

      Classification: 28a, 32a
      119 079
      Transfer of silica gel TLC screening methods for clarithromycin, azithromycin, and amodiaquine + artesunate to HPTLC–densitometry with detection by reagentless thermochemical activation of fluorescence quenching
      E. ARMOUR, J. SHERMA* (*Department of Chemistry, Lafayette College, Easton, Pennsylvania, USA, shermaj@lafayette.edu)

      J. Liq. Chromatogr. Relat. Technol. 40, 22-286 (2017). HPTLC of clarithromycin (1), azithromycin (2), and amodiaquine (3) and artesunate (4) on silica gel with methanol – ethyl acetate – concentrated ammonium hydroxide 40:10:1 for (1) and (2) and acetone – water – concentrated ammonium hydroxide 40:7:2 for (3) and (4). Detection by heating for 15 and 30 min, respectively, for (1) and (2) at 160 °C to activate fluorescence quenching. Naturally fluorescence quenching zones of (3) were scanned at 254 nm and (4) after heating the plate for 5 min at 180 °C to activate fluorescence quenching.

      Classification: 28a, 32a
      121 080
      Validated HPTLC and HPLC methods for determination of fluorometholone and sodium cromoglycate in presence of their impurities and degradation products, application to kinetic study and on rabbit aqueous humor
      M. HEGAZY, M. ABDELWAHAB*, H. HENDAWY, S. WESHAHY, S. ABBAS (*National Organization for Drug Control and Research (NODCAR), 6 Abu-Hazem St. from El-Haram St., Giza 12652, Egypt, mai.hassan2012@yahoo.com)

      J. Liq. Chromatogr. Relat. Technol. 31, 203-222 (2018). HPTLC of fluorometholone (1) and sodium cromoglycate (2) on silica gel with ethyl acetate – methanol 9:1. Quantitative determination by absorbance measurement at 240 nm. The hRf values for (1) and (2) were 65 and 12, respectively. Linearity was in the range of 0.1-24.0 μg/zone for (1) and 0.2-48.0 μg/zone for (2). The intermediate precision was below 1.1 % (n=9). The LOD and LOQ were 9 and 270 ng for (1) and 170 and 510 ng for (2), respectively. Average recoveries for (1) and (2) were 100.3 and 100.7 %, respectively.

      Classification: 32a
      122 087
      Validated stability-indicating high-performance liquid chromatography and thin-layer chromatography methods for the determination of zopiclone in pharmaceutical
      formulation
      S. RAZEQ, S. SOLIMAN*, A. MOHAMED (*Analytical Chemistry Departments, Faculty of Pharmacy, AlAzhar University, Cairo, Egypt, suzansoliman1961@hotmail.com)

      J. Planar Chromatogr. 31, 297-308 (2018). HPTLC of zopiclone in the presence of its degradation products, namely, 7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl-4-methylpiperazine-1-carboxylate (hydrolytic DEG) and 5H-pyrrolo[3,4-b]pyrazine-5,7(6H)-dione (oxidative DEG) on silica gel with ethyl acetate – methanol – ammonia 33% 17:2:1. Quantitative determination by absorbance measurement at 303 nm. The hRF value for zopiclone was 44. Linearity was between 0.1 and 2 μg/zone. LOD and LOQ were 30 and 80 ng/zone. The intermediate precision was <2 % (n=3). Average recovery was 99.5 %.

      Classification: 32a
      56 141
      Two-dimensional thin-layer chromatographic identification of twelve 1,4-benzodiazepines
      M. BAKAVOLI, V. NAVARATNAM, N. NAIR

      J. Chromatogr. 299, 465-470 (1984). TLC of benzodiazepines on silica with chloroform - acetone 9:1 for the first direction and dichloromethane - chloroform 1:1 for the second after on-plate acidic hydrolysis of the unresolved spots with NH3 -solution in methanol. Examination under UV 254 and 366 mm.

      Classification: 32a
      56 175
      Drug Res
      H. TILLIAN, G. GUEBITZ, W. KORSATKO, R. WINTERSTEIGER

      35, 552-554 (1985). (Fluorodensitometric determination of Michael-adducts of alpha, beta-unsaturated aldehydes in biological material.) Determination of Michael-adducts and aldehydes on silica with isopropanol - methyl acetate - methanol - conc. NH3 50:5:30:20 (for adducts) and chloroform - petrol ether - acetone 7:1:2 (for aldehydes). Quantification as dansyl hydrazine derivatives by fluorescence scanning.

      Classification: 32a
      58 134
      Analysis of benzodiazepines
      M. CHIAROTTI, N. DE GIOVANNI, A. FIORI

      I. Chromatographic identification. J. Chromatogr. 358, 169-178 (1986). TLC of 19 benzodiazepines on silica with a) benzene -2-propanol -30 % NH3 85:15:1, b) ethyl acetate - methanol -30 % NH3 85:10:5, c) toluene - acetone - ethanol -30 % NH3 45:45:7:3, d) chloroform - acetone 9:1 and e) ethyl acetate - cyclohexane -30 % NH3 50:40:0.1. Detection by UV and spraying with Dragendorff and Bratton-Marshall reagents.

      Classification: 32a