J. Planar Chromatogr. 5, 334-337 (1992). Discussion of the possibility of calculating optimum values of the differences in chromatographic parameters for the components of separated mixtures on the basis of a retention model based on the law of mass action. The comparison of calculated values with those obtained experimentally on silica eluted with various mixed mobile phases has demonstrated the usefulness of the method.

Anal. Chem. 67, 4423-4430 (1995). Presentation of both first and second-order regression models that relate retention, as the Rf of individual solutes, the log k' of individual solutes, or the average Rf of a mixture of solutes, to the properties of the weak solvent in each of a series of 25 binary mobile phases consisting of a specified concentration of ethyl acetate as a common strong solvent. The stepwise procedure is used for constructing these models, which are for either simulated or experimental separations on silica. Substances chromatographed: Steroids, p-nitrobenzyl esters of dansyl amino acids.

Sz. Nyiredy, A. Kakuk (eds.): Planar Chromatography 2000, Lillafüred, Hungary, 24-26 June 2000, Res. Inst. for Med. Plants, p. 219-229. OPLC of 13 benzodiazepines on HPTLC silica gel with various calculated solvent mixtures up to 15 cm after a pre-run with acetone.

Chromatogr. Sci. 55, 71-85 (1991). A review with 50 references. Discussion of general optimization techniques that can be used in the different steps of the TLC process. Method for the choice of solvent in the chromatographic separation step are given.

Chromatographia 35, 149-152 (1993). Description of a computer-assisted mixture design simplex method for the optimization of the solvent system. Separation of a mixture of 5 benzoic acid derivatives in reverse-phase and of 12 PTH-amino acids in normal phase. Method demonstrated using a two-factor selectivity rectangle concept and a special polynomial regression of 9 TLC runs, with the Rf difference as the selection criterion and with connection to a general simplex method.

Dünnschicht-Chromatographie. InCom Sonderband 1996, 124-138. Comparison of six different optimization methods based on the relationship of coupling the retention parameters with the binary mobile phase composition, as proposed by Snyder, Schoenmakers, Lu Peichang and Lu Xaoming, Purnell, Kowalska, and Horvath and Melander.

J. Planar Chromatogr. 12, 365-372 (1999). Development of a computer program for optimization of mobile phase composition in TLC and examination of this method for chromatography of cyanobacterial hepatotoxins on normal-phase TLC plates and for phenolic compounds on RP layers. HPTLC of microcystins (cyclic heptapeptides) on silica gel with combinations of n-propanol - ethyl acetate - water. Densitometry at 240 nm. TLC of phenolic acids (catechin, ellagic acid, gallic acid, kaempferol, methyl gallate, rutin) on RP-18. Videodensitometry at 254 nm.

J. Planar Chromatogr. 3, 326-330 (1990). Optimization of mobile phase composition for the separation of phenylurea and s-triazine herbicides on silica by means of the „ELUO“ method in which solvents are selected from an eluotropic series based on solvent power. The method is complementary to the „PRISMA“ method for optimizing the compositions of binary, ternary and quaternary mobile phases for OPLC, or even HPLC and HPTLC. TLC of 13 herbicides on silica with five different binary solvent systems.