Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
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      125 055
      Thin-layer chromatographic enantioseparation of atenolol and propranolol using (S)-naproxen as chiral selector: direct and indirect approaches
      V. VASHISTHA, R. BHUSHAN* (*Department of Chemistry, GLA University, Mathura, Uttar Pradesh 281406, India, rbushfcy54@gmail.com)

      J. Planar Chromatogr. 33, 101-107 (2020). HPTLC of (RS)-atenolol and (RS)-propranolol on silica gel  impregnated with 50 mM (S)-naproxen as chiral selector with acetonitrile - dichloromethane - water 6:2:1 pH = 5 for (RS)-atenolol and 7:3:1 pH = 5 for (RS)-propanolol. Detection by exposure to iodine vapor. The LOD was 1.2 and 1.6 µg/mL for (1) and (2), respectively. The chiral selector allowed the separation of atenolol and propranolol with a resolution of 2.4.

      Classification: 38
      124 019
      Thin-layer chromatographic enantioresolution of (RS)-ketorolac using L-amino acids as chiral additive in stationary phase
      M. SINGH*, R. BHUSHAN (*Department of Chemistry, Lovely Professional University, Phagwara 144411, Punjab, India, manishasingh2283949@gmail.com)

      J. Planar Chromatogr. 32, 475-479 (2019). TLC of enantiomers of (RS)-ketorolac on home-made silica gel plates impregnated with L-Tryp (1), L-Val (2), L-Met (3) or L-His (4) with acetonitrile - methanol - water - chloroform 9:5:2:4 for (1), acetonitrile - methanol - water - dichloromethane 6:2:1:1 for (2), acetonitrile - methanol - water - chloroform 5:3:1:1 for (3) and acetonitrile - methanol - water - chloroform 10:4:1:5 for (4), respectively. Detection by exposure to iodine vapors. The hRF values for (S)-(‒)- and (R)-(+)-ketorolac were 36 and 81 for (1), 30 and 79 for (2), 30 and 87 for (3) and 42 and 85 for (4), respectively. LOD was 0.4 μg/mL.

      Classification: 38
      123 060
      Superiority of Thin-Layer Chromatography over High-Performance Liquid Chromatography in enantioseparation
      D. SINGH, P. MALIK, R. BHUSHAN (*Department of Chemistry, Indian Institute of Technology Roorkee, Roorkee 247667, India, rbushfcy54@gmail.com)

      J. Planar Chromatogr. 32, 7-12 (2019). HPTLC of (RS)-mexiletine on RP-18 plates impregnated with 0.03 mM bovine serum albumin as chiral additive with acetonitrile - dichloromethane - methanol 1:1:1. Detection by exposure to iodine vapors. Resolution was 2.3 for the HPTLC method and 1.9 using an HPLC method. The HPTLC analysis took nearly 7 min, whereas HPLC took nearly 265 min to get the results.

      Classification: 38
      102 165
      Enantioseparation of S,R-(+/-)-ketoprofen on plain silica gel layers with achiral mobile phase
      M. SAJEWICZ, G. GRYGIERCZYK, M. GONTARSKA, Teresa KOWALSKA* (*Institut of Chemistry, Silesian University, 9 Szkolna Street, 40-006 Katowice, Poland; kowalska@us.edu.pl)

      J. Liq. Chromatogr. Relat. Technol. 30, 2185-2192 (2007). TLC of S,R-(+/-)-ketoprofen on silica gel (prewashed with methanol - water 9:1) with acetonitrile - water 5:1 containing several drops of acetic acid. Quantitative determination by absorbance measurement at 252 nm. Three different components of the investigated mixture were found which were again separated two-dimensionally in the one dimensional development mode, i. e., their positions differed in terms of the hRf values and the respective migration tracks of these three species all deviated to the right. Earlier tests showed that silica gel employed in the planar chromatographic mode enables two-dimensional enantioseparation of the racemic mixtures in the one-dimensional development mode, without using chiral mobile phases. In the present study this effect was investigated with another racemic mixture from the group of profens. It was concluded that the two-dimensional enantioseparation in the one-dimensional planar chromatographic mode on the microcrystalline silica gel layers is a promising option, enhancing the enantioseparative potential of planar chromatography that cannot be challenged by the column liquid chromatography.

      Classification: 38
      112 138
      Direct enantiomeric resolution of (±)-bupropion using chiral liquid chromatography
      R. BHUSHAN*, S. BATRA (*Department of Chemistry, Indian Institute of Technology, Roorkee, India, rbushfcy@iitr.ernet.in)

      J. Planar Chromatogr. 26, 491-495 (2013). TLC of enantiomers of (±)-bupropion on silica gel, impregnated with L-Glu, with acetonitrile - methanol - dichloromethane - water 28:5:11:5. Detection by exposition to iodine vapor. LOD was 0.2 µg/zone for each enantiomer.

      Classification: 38
      62 132
      Thin-layer chromatographic enantiomeric resolution via ligand exchange
      K. GÜNTHER, (Fachbereich Forsch. Chemie, Degussa AG, Postfach 1345, D-6450 Hanau, FRG)

      J. Chromatogr. 448, 11-30 (1988). TLC of proteinogenic and non-proteinogenic amino acids, dipeptides and a-hydroxy acids. Separation of the enantiomers, without derivatization, on a chiralplate. Quantification by densitometry. Determination of the respective enantiomers at trace levels (0,25%). Detection limits: 0.1% of the minor enantiomer. Other examples from the field of +-methyl, N-alkyl and halogenated amino acids.

      Classification: 18a, 18b, 38
      67 241
      Chiral separations
      J.D. DUNCAN, (Dep. Chem., Univ. Missouri-Rolla, Rolla, Missouri 65401, USA)

      J. Liquid Chromatogr. 13, 2737-2755 (1990). Comparison of separations attained in normal phase HPLC and TLC involving N-carbobenzyloxy-glycyl-L-proline and (+/-)-10-camphorsulfonic acid as chiral mobile phase additives/chiral counterions (CMA). Discussion of the reasons for differences in chiral stationary phases, and of the differences in solubility and proposed separation mechanisms for native cyclo dextrin versus derivatized species. Outline of inherent differences in HPLC and TLC methods.

      Classification: 38
      71 200
      Reversed phase planar chromatography of enantiomeric compounds with bovine serum albumin in the mobile phase
      L. LEPRI*, V. COAS, P.G. DESIDERI, L. PETTINI, (*Dept. of Publ. Health, Epidemiology and Environmental Anal. Chem., Univ. of Florence, Via G. Capponi 9, 50121 Florence, Italy)

      J. Planar Chromatogr. 5, 364-367 (1992). TLC of 4 DL MTH-amino acids (MTH-DL-Phe, MTH-DL-Tyr, MTH-DL-Trp, MTH-DL-Pro) on RP-18 silica by eluting with aqueous - organic solutions containing bovine serum albumine (BSA) and buffers of different pH values.

      Keywords:
      Classification: 18a, 38