Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
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      72 165
      An investigation of drug detection in equine urine samples by modern TLC
      M.R. TAYLOR, S.A. WESTWOOD, (Horseracing Forensic Laboratory Ltd., P.O. Box 15, Snailwell Road, Newmarket, Suffolk CB8 7DT, UK)

      J. Planar Chromatogr. 6, 415-418 (1993). TLC of 4 drug mixtures (hydroxyethyltheophylline/sulfadimidine, hydroflumethiazide/theophylline, carprofen/flunixin, frusemide/caffeine) and 11 corticosteroids on silica with 5 different mobile phases (ethyl acetate - methanol 0.880 NH3 80:25:10; dichloromethane - dioxan - water 100:50:50; lower layer; chloroform - methanol 95:5; toluene - ether - acetic acid - water 120:60:18:1. Detection and/or quantification by densitometry (no details).

      Classification: 32e
      76 037
      Identification of LSD, MBDB, and atropine in real samples with on-line HPTLC-FTIR coupling
      A.M. PFEIFER, K.-A. KOVAR*, (Pharm. Inst. der Univ. Tübingen, Auf der Morgenstelle 8, D-72076 Tübingen, Germany)

      J. Planar Chromatogr. 8, 388 - 392 (1995). HPTLC of MDA.HCl, MDMA.HCl, MDE.HCl, BDB.HCl, MBDB.HCl, LSD, and atropine on silica with dichloromethane - methanol 200:3 in the presence of NH3 in a separate 10 mL glass vessel for LSD, ethyl acetate - acetone - methanol - 25% NH3 50:50:20:1 for MBDB, acetone - ethanol - 25% NH3 90:7:3 for atropine. Identification by in situ FTIR measurement.

      Keywords: toxicology doping
      Classification: 4e, 32d
      95 064
      (Determination of astragaloside in Zilongjin tablets by thin-layer chromatography) (Chinese)
      J. GUO (Guo Jingqiang)*, R. NIU (Niu Ruijie), G. HUANG (Huang Guifen) (*Tianjin municip. Inst. Drug Cont., Tianjin 300070, China)

      J. Chinese Trad. and Herb. Drugs (Zhongcaoyao), 36 (2), 222-224 (2005). TLC on silica gel with chloroform - methanol - water 70:35:4. Detection by spraying with 10 % H2SO4 in ethanol and heating at 105 °C for 5 min. Identification by fingerprint technique. Quantification by densitometry at 530 nm. Validation of the method by investigation of linearity (0.458 µg - 2.748 µg, r = 0.998); precision (RSD = 2.48 %, n = 5 within plate and RSD = 4.69 % plate to plate); reproducibility of five time assay towards the same sample (RSD = 2.41 %); and standard addition recovery (96.11 %, RSD = 1.91 %, n = 5). The results for real life samples are given.

      Classification: 32c
      101 047
      A validated stability-indicating TLC method for determination of forskolin in crude drug and pharmaceutical dosage form
      S. AHMAD*, M. RIZWAN, Rabea PARVEEN, M. MUJEEB, M. AQUIL (*Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Hamdard University, New Delhi, 110062, India, sahmad_jh@yahoo.co.in)

      Chromatographia 67 (5-6), 441-447 (2008). HPTLC of forskolinon on silica gel aluminium foil with benzene - methanol 9:1. Quantitative determination by densitometry in the absorbance mode at 545 nm after spraying with anisaldehyde sulphuric acid reagent. The method was validated: linearity was between 100 and 1000 ng/spot (r = 0.994) and the limits of detection and quantification were 8 and 27 ng/spot respectively. Application of the proposed method for determination of forskolin in Coleus forskohlii root and in capsule dosage forms, which showed 0.18 and 0.57 % w/w of forskolin, which was subjected to acid and alkali hydrolysis, oxidation, photodegradation and heat degradation. The method shows good repeatability, selectivity and accuracy, and effectively separates forskolin from components of C. forskohlii root, from excipients of capsule as well as the degradation products of forskolin. It can be used for routine analysis and as a stability-indicating method.

      Classification: 32c
      95 084
      (Determination of chlorogenic acid in Liyin tablets by thin-layer chromatography) (Chinese)
      L. SHEN (Shen Linni)*, H. YU (Yu Haihong), Y. ZHENG (Zheng Yan) (*Zhejiang Deqing County TCM Hosp., Deqing, Zhejiang 313200, China)

      Chinese J. Hosp. Pharm. (Zhongguo Yiyuan yaoxue Zazhi) 25 (1), 90-92 (2005). TLC on silica gel with chloroform - ethyl acetate - formic acid 2:2:1. Detection under UV light. Identification by fingerprint technique. Quantification by densitometry at 325 nm. Validation of the method by investigation of linearity (0.52 µg - 4.68 µg, r = 0.9992); precision (RSD = 2.20 %, n = 5); reproducibility of five time assay towards the same sample (RSD = 3.10 %); standard addition recovery (99.0 %, RSD = 0.26 %, n = 5). The results for three real life samples are given.

      Classification: 32c
      101 094
      Stability-indicating HPTLC determination of imatinib mesylate in bulk drug and pharmaceutical dosage form
      N. VADERA*, G. SUBRAMANIAN, P. MUSMADE (*Department of Pharmaceutical Quality Assurance, Manipal College of Pharmaceutical Sciences, Manipal, Karnataka 576104, India)

      J. Pharm. Biomed. Anal. 43 (2), 722-726 (2007). HPTLC of imatinib mesylate both as a bulk drug and in formulations on silica gel aluminium plates with chloroform - methanol 3:2. Quantitative determination by absorbance measurement at 276 nm. Linearity was between 100 and 1000 ng per spot. The limit of detection and quantitation was 10 and 30 ng, respectively. The method is repeatable, selective and accurate and can be used for stability control.

      Classification: 32c
      95 097
      (Study of the quality standard for Buxie Danggui extract) (Chinese)
      M. XIN (Xin Meiyu) (Guangdong Wannianqing Pharm. Co., Ltd., Shantou, Guangdong 515031, China)

      Chinese J. Trad. Pat. Med. (Zhongchengyao) 27 (2), 225-227 (2004). TLC on silica gel with 1) petroleum ether (30 - 60 ºC) - ethyl acetate 9:1; 2) benzene - glacial acetic acid 4:1. Detection 1) by spraying with 1 % vanillin solution and heating at 105 ºC for 10 min; 2) under UV 365 nm. Identification by fingerprint technique. Quantification of ferulic acid by densitometry at 325 nm. Validation of the method by investigation of linearity (0.16 µg - 1.6 µg, r = 0.9992); precision (RSD = 1.8 %, n= 5 within plate and RSD = 2.3 % plate to plate); reproducibility of five time assay towards the same sample (RSD = 0.5 %); and standard addition recovery (97.17 %, RSD = 0.9 %, n = 5). The results for three real life samples are given.

      Classification: 32c
      103 006
      Chemometric analysis of retention data from salting-out thin-layer chromatography in relation to structural parameters and biological activity of chosen sulphonamides
      Jolanta FLIEGER*, R. SWIEBODA, M. TATARCZAK (*Department of Inorganic and Analytical Chemistry, Medical University of Lublin, 20-081 Lublin, Staszica 6, Poland)

      J. Chromatogr. B 846 (1-2), 334-340 (2007). Salting-out TLC of sulphonamides on silica gel with aqueous solutions of salts (sulphates, chlorides, nitrates, phosphates, acetates, and thiocyanates) showed that the applied salts have different effects on the retention of sulphonamides according to Hofmeister's classification (e.g. kosmotropes, chaotropes and neutral). Parameters of the linear regression analysis were compared with QSAR data of dependences between the RM values and salt concentration. Chromatographic data obtained by salting-out TLC showed not only the physico-chemical properties of the examined compounds but also information about their activity. The method was suitable for prediction and classification of sulphonamide drugs by localization of other structurally similar compounds with antagonistic activity towards sulphonamides.

      Classification: 2c