Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
  • Browse and search by CBS classification: Select one of the 38 CBS classification categories where you want to search by a keyword
  • Keyword register: select an initial character and browse associated keywords
  • Search by CBS edition: Select a CBS edition and find all related publications

Registered users can create a tailor made PDF of selected articles throughout CCBS search – simply use the cart icon on the right hand of each abstract to create your individual selection of abstracts. The saved items can be printed to PDF using the print function of your web browser.

      103 070
      Characterization of metabolites of fungicidal cymoxanil in a sensitive strain of Botrytis cinerea
      F. TELLIER*, R. FRITZ, L. KERHOAS, P. DUCROT, J. EINHORN, A. SINCLAIR, P. LEROUX (*Department of Chemistry, Versailles Saint-Quentin-en-Yvelines University, 78001 Versailles, France, ftellier@versailles.inra.fr)

      J. Agric. Food Chem. 56, 8050-8057 (2008). HPTLC of [2-14C]-cymoxanil in the cultures (medium and mycelium) and in the cell-free extracts of Botrytis cinerea on silica gel with hexane - ethyl acetate - acetic acid 70:30:1. The most polar products were separated on RP-18 (impregnated with a methanolic solution of tetrabutylammonium bromide 70 mM and dried at 80 °C for 5 min) with phosphate buffer (0.01 M, pH 6) – methanol 11:9. Detection by autoradiography. The hRf value of cymoxanil was 35 on silica gel. Different metabolites were detected using both stationary phases.

      Classification: 23e
      120 001
      Thin layer chromatography in drug discovery process
      K. CIURA*, S. DZIOMBA, J. NOWAKOWSKA, M.J. MARKUSZEWSKI (*Dep. of Phys. Chem., Fac. of Pharm., Med. Univ. of Gdansk, 107 Hallera Street, 80-416 Gdansk, Poland, krzemek@gumed.edu.pl)

      J. Chromatogr. A 1520, 9-22 (2017). A review focused on application of TLC as simple, rapid, popular and inexpensive method for lipophilicity assessment. Discussion of the principles and methodology of quantitative structure retention relationship (QSRR) employed for lipophilicity prediction from retention data. Comparison of traditional and unconventional TLC systems applied for lipophilicity assessment. Overview of the applications of TLC retention constants and use of bioautography as a TLC method complementary in quantitative structure activity relationship (QSAR) studies. Discussion of the advantages and limitations of the method, and application of less common planar chromatography modes for drug discovery process.

      Keywords: autoradiography
      Classification: 1, 2c
      67 169
      Photolysis of imazapyr (Ac 243997) herbicide in aqueous media
      N.M. MALLIPUDI, S.J. STOUT, A.R. DA CONHA, A.U. LEE, (Agric. Res. Div., American Canamid Comp., P.O. Box 400, New Jersey 08543-0400, USA)

      J. Agric. Food Chem. 39, 412-417 (1991). Analytical and preparative TLC on silica with 7 solvent systems (e.g. dichloromethane - ether 1:1), visualization by autoradiography or by UV; quantification after scraping by liquid scintillation. Also two-dimensional TLC.

      Classification: 29d
      95 001
      (Application of TLC-bioautography in drug screening)
      J. QU (Qu Jianbo)*, H. LOU (Lou Hongxiang), P. FAN (Fan Peihong) (*School Pharm., Shandong Univ., Jinan 250012, China)

      (Chinese) J. Chinese Trad. and Herb. drugs 36 (1), 132-137 (2005). A review with 22 references on TLC-bioautography, including the screening of natural compounds with antibacterial and/or antifungal activity, cholinesterase inhibitors, free radical eliminators, and antioxidants. Discussion of the advantages of the technique compared to other related techniques.

      Classification: 1, 32
      104 050
      HPTLC determination of cefuroxime axetil and ornidazole in combined tablet dosage form
      P.N. RANJANE*, S.V. GANDHI, S.S. KADUKAR, K.G. BOTHARA, (*Department of Pharmaceutical Analysis, A.I.S.S.M.S. College of Pharmacy, Kennedy Road, Near R.T.O., Pune 411 001, India)

      J. Chromatogr. Sci. 48 (1), 26-28 (2010). HPTLC of cefuroxime axetil and ornidazole in combined tablet dosage form on silica gel with toluene - n-butanol - triethylamine 17:4:1. The hRf value of ornidazole was 51 and of cefuroxime axetil 67. Quantification by densitometry at 285 nm. Linearity was between 100 and 500 ng/band for both cefuroxime axetil and ornidazole. The method was used for the assay of the compounds in pharmaceutical formulations. The content of cefuroxime axetil was 102.4 % and of ornidazole 101.0 %.

      Classification: 28a
      57 147
      Metabolism of isouron (3-(5-ter-butyl-3-isoxarelyl)-1,1-dimethylurea)
      M. ISHIZUKA, Y. KONDO, T. NAGARE, Y. TAKEUCHI

      Rapid conversion of the herbicide to ten thytoxic metabolites in a resistant plant, sugarcane. J. Agric. Food Chem. 33, 1070-1075 (1985). TLC and HPTLC separation of isouran and metabolites on silica or RP-8 plates with ether - acetone - chloroform - methanol 9:1, chloroform - methanol - pyridine - acetic acid 15:3:1:1 and methanol - water 7:3. Detection by autoradiography. Comparison with standards.

      Classification: 29
      67 211
      Biotransformation of nimodipine in rat, dog, and monkey
      D. SCHERLING, K. BÜHNER, H.P. KRAUSE, W. KARL, C. WÜNSCHE, (Inst. of Pharmacokinetics, Centr. Res. and Anal. Dept. of Bayer AG; Wuppertal, FRG)

      Arzneim.-Forsch./Drug Res. 41, 392-398 (1991). TLC of nimodipine ((±)3-isopropyl 5-(2-methoxyethyl)1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-pyridine-3,5-dicarboxylate) and metabolites on silica with chloroform - methanol - water - acetic acid 65:28:4:4; 2D TLC using toluene - acetone - acetic acid 70:25:5 and toluene - acetone 1:1. Detection by autoradiography and scintillation.

      Classification: 32b
      95 003
      Planar displacement chromatography
      H. KALÁSZ (Semmelweis University, Department of Pharmacology and Pharmacotherapy, H-1089 Budapest, Nagyvárad tér 4, Hungary)

      J. Planar Chromatogr. 17, 464-467 (2004). Displacement chromatography (DC) has been widely used to separate metabolites with similar chemical characteristics. DC works with highly overloaded sample sizes, which are normal for samples not subjected to clean-up. DC successfully handels samples which contain high concentrations of salts and/or proteins, and results in consecutive steps of displaced compounds rather than Gaussian curves. Planar displacement chromatography (DTLC) is suitable for seeking new metabolites in excreted body fluids. Transfer of the radiolabeled methyl group can easily be proven using spacer-displacement planar chromatography. Displacement TLC of L-deprenyl and 14C-L-deprenyl on silica gel with chloroform - triethanolamine 19:1. Detection by X-ray film with an exposure time of 120 h.

      Classification: 2, 32a