Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
  • Browse and search by CBS classification: Select one of the 38 CBS classification categories where you want to search by a keyword
  • Keyword register: select an initial character and browse associated keywords
  • Search by CBS edition: Select a CBS edition and find all related publications

Registered users can create a tailor made PDF of selected articles throughout CCBS search – simply use the cart icon on the right hand of each abstract to create your individual selection of abstracts. You can export your saved items to PDF by clicking the download icon.

      71 043
      On-line coupling of HPLC, solid phase extraction, and TLC (HPLC-OSP-TLC)
      E. MÜLLER, H. JORK*, (*Univ. des Saarlandes, Fachber. Pharmazie u. Biol. Chem., Gebäude 12, D-6600 Saarbrücken, Germany)

      J. Planar Chromatogr. 6, 21-28 (1993). Description of on-line coupling of HPLC, solid phase extraction (OSP), and TLC. The technique opens up new possibilities in the field of multidimensional chromatography of complex samples. Using the OSP-2 apparatus the HPLC eluent is exchanged by the inclusion of an on-line solid phase extraction step between the two chromatographic processes. This on-line coupling has been used for the quantitative determination of 4(5)-methylimidazole in caramel.

      Classification: 4d
      73 111
      A new spray reagent for selective detection of dichlorvos by thin-layer chromatography
      V.B. PATIL*, M.S. SHINGARE, (*Dept. Chem., Marathwada Univ., Aurangabad - 431004, India)

      Talanta 41, 367-369 (1994). Dichlorvos in the presence of moisture breaks down to dichloroacetaldehyde which in turn reacts with phenylhydrazine hydrochloride to give a yellowish red color. In acidic media the color is intensified and the detection sensitivity increases. The reagent is selective for dichlorvos. Investigation of the interference with other insecticides, etc.

      Classification: 29b
      94 050
      A simple and sensitive HPTLC method for estimation of gatifloxacin in tablet dosage forms
      S. A. SHAH, I. S. RATHOD, B. N. SUHAGIA, Meeta BALDANIYA (Department of Quality Assurance, L. M. College of Pharmacy, Navarangpura, Ahmedabad 380009, India)

      Indian J. Pharm. Sci. 66 (3), 306-308 (2004). HPTLC on silica gel with n-butanol - methanol - 6 M ammonia 5:1:2. Gatifloxacin showed Rf values of 0.47 ± 0.03. Quantitative determination by absorbance measurement at 292 nm. The method was validated in terms of linearity (400-1200 ng/spot), precision (intra-day variation 1.3 to 3.2 %, inter-day variation 3.9 to 5.0 %), accuracy (93.3 to 99.4 %), and specificity. The limit of detection and limit of quantification for gatifloxacin were found to be 10 ng/spot and 50 ng/spot respectively. The method is simple, sensitive, precise, and can be used for the routine quality control testing of marketed tablet formulations (400 mg).

      Classification: 32a
      95 060
      Development and validation of a new sensitive method for the simultaneous estimation of amlodipine - atenolol in tablets by HPTLC
      M. G. PAI*, Dattesh VEREKAR, K. VENKATESHWAR RAO (*Goa College of Pharmacy, Panaji, Goa, India)

      IPC 56th 2004, Abstract No. GP-5. Simultaneous HPTLC determination of amlodipine and atenolol on silica gel with ethyl acetate - methanol - ammonia 60:40:3. Quantitative determination by scanning at 254 nm. The method was found linear in the range of 0.5 – 5.0 mg/mL amlodipine and 5.0 mg – 50 mg/mL atenolol. Recovery was 98.11 – 101.5 % for both of the compounds. The method was validated for accuracy, precision, linearity, specificity, LOD, and LOQ.

      Classification: 32a
      96 036
      Separation of eight selected flavan-3-ols on cellulose thin-layer chromatographic plates
      Irena VOVK*, Breda SIMONOVSKA, H. VUORELA (*Laboratory for Food Chemistry, National Institute of Chemistry, Hajdrihova 19, 1001 Ljubljana, Slovenia)

      J. Chromatogr. A 1077 (2), 188-194 (2005). HPTLC of (+)-catechin (C), (-)-epicatechin (EC), (-)-gallocatechin (GC), (-)-epigallocatechin (EGC), (-)-epicatechin gallate (ECg), (-)-epigallocatechin gallate (EGCg), procyanidin B1, and procyanidin B2 on cellulose prewashed with water (not necessary, when water was used as developing solvent) and dried with a hair dryer, with 1) water; 2) 1-propanol - water 1:4; 3) 1-propanol - water - acetic acid 4:2:1; 4) 1-propanol - water - acetic acid 2:8:1 in horizontal developing chamber (sandwich configuration). Detection with vanillin - H3PO4 reagent. Water enabled the separation of epimers C from EC and GC from EGC, as well as the dimers procyanidin B1 and B2. Additionally C, EGC, B1 and B2 were separated from all the other compounds. The best separation of the five main catechins (EC, GC, EGC, ECg, EGCg) present in green tea extract was achieved using 1-propanol - water - acetic acid 2:8:1. The chromatograms of oak bark extract developed in solvents with higher water content (1-propanol - water 1:4 and 1-propanol - water - acetic acid 2:8:1) showed less bands than chromatograms developed in solvents with higher organic modifier content (e.g. 1-propanol - water - acetic acid 4:2:1). It was proved that such behavior was due to the presence of procyanidins beside the main component catechin.

      Classification: 8b
      99 101
      Validated High Performance Thin Layer Chromatography Method for Simultaneous Estimation of Ofloxacin and Ornidazole in Tablet Dosage Form
      M. GANDHIMATI*, T. K. RAVI, Nilima SHUKLA (*Department of Pharmaceutical Analysis,Sri Ramkrishna College of Pharmacy, 395, Sarojini Naidu Road, Coimbatore 641044, India)

      Ind. J. Pharm. Sci. 68 (6), 838-840 (2006). HPTLC of ofloxacin and ornidazole in tablet dosage form on silica gel with n-butanol - ethanol - ammonia 5:5:4. Quantitative determination by absorbance measurement at 295 nm. The method was found to be linear in the concentrate range of 1-5 ng/spot with recovery of 99.5-102.5 % for both compounds. The method was validated for linearity, accuracy, precision, repeatability, and specificity.

      Classification: 32a
      100 012
      Coralyne cation, a fluorescent probe for general detection in planar chromatography
      Elena MATEOS, V.L. CEBOLLA*, L. MEMBRADO, J. VELA, Eva GALVEZ, Muriel MATT, F.P. COSSIO (*Instituto de Carboquímica, CSIC, P.O. Box 549, 50080 Zaragoza, Spain; vcebolla@carbon.icb.csic.es)

      J. Chromatogr. A 1046 (2), 251-257 (2007). Fluorescence scanning densitometry of various analytes on HPTLC silica gel plates impregnated with a solution of coralyne cation, based on the increase or decrease, that the corresponding analyte induces on native coralyne emission at a given excitation wavelength. Compared to a procedure previously described for berberine cation, and Reichardt's dye probes, the sensitivity of coralyne in HPTLC detection of non-fluorescent, structurally different analytes (e.g. long-chain alkanes, alcohols, alkylbromides, neutral lipids) is superior.

      Classification: 3e
      102 030
      Analytical and densitometric evaluation of visualizing reagents of selected aliphatic compounds on thin layer
      Alina PYKA*, W. KLIMCZOK (*Faculty of Pharmacy, Department of Analytical Chemistry, Medical University of Silesia, 4, Jagiellonska Str., 41-200 Sosnowiec, Poland; apyka@slam.katowice.pl)

      J. Liq. Chromatogr. Relat. Technol. 31, 1492-1510 (2008). TLC of stearic acid, stearyl alcohol, and methyl stearate on silica gel (prewashed with methanol) with methanol - chloroform 1:1 followed by drying for 24 h at room temperature. Six new derivatization reagents were evaluated: gentian violet, methylene violet, methylene blue, methyl green, malachite green, and Janus blue. Detection by dipping for 5 s, followed by drying for 24 h at room temperature. Quantitative determination by absorbance measurement. The results obtained indicate that all of the new derivatization reagents give better results than the universally applied Rhodamine B. The best reagents for quantitative determination of stearic acid are methylene blue and Janus blue, for stearyl alcohol malachite green and Janus blue, and for methyl stearate methylene blue, Janus blue, and malachite green.

      Classification: 11a