Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
  • Browse and search by CBS classification: Select one of the 38 CBS classification categories where you want to search by a keyword
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Registered users can create a tailor made PDF of selected articles throughout CCBS search – simply use the cart icon on the right hand of each abstract to create your individual selection of abstracts. You can export your saved items to PDF by clicking the download icon.

      74 033
      Determination of edetic acid (EDTA) in water by on-line coupling of HPTLC and FTIR
      S.C. WOLFF, K.-A. KOVAR*, (Pharm. Inst. der Univ. Tübingen, Auf der Morgenstelle 8, D-72076 Tübingen, Germany)

      J. Planar Chromatogr. 7, 286-287 (1994). HPTLC of EDTA of an authentic sample of surface water on silica prewashed with acetone - dichloromethane 1:9 by AMD, using a 30 step gradient based on ammoniacal methanol - dichloromethane. Scanning by FTIR. The method has been validated for 0.5 - 3.75 µg EDTA; validated limits of detection and determination were calculated to be 250 and 450 ng, respectively. Samples containing from 10 to 100 µg/L EDTA can be analyzed without derivatization.

      Classification: 4e, 11
      78 001
      Duennschichtchromatographie (Thin-layer Chromatography)
      K.A. KOVAR, Gertrud E. MORLOCK*, (CAMAG, Sonnenmattstr. 11, 4132 Muttenz, Switzerland)

      in H. Naumer, W. Heller (Ed.): Untersuchungsmethoden in der Chemie - Einführung in die moderne Analytik, Georg Thieme Verlag Stuttgart, New York, 57-70, ISBN 3-13-681403-7 (1997). Descriptions of advantages and basics in TLC/HPTLC like stationary phase, mobile phase and PRISMA model, factors of influence, measurement of absorbance and fluorescence. Different techniques for development of an TLC/HPTLC plate are illustrated and special automated devices for application, chromatography, detection, quantification and documentation. The principle of in-situ detection and identification methods, like microchemical, microbiological or enzymatic reactions, are given. Additionally special in-situ detection, identification methods (FTIR, Raman and MS), and on-line coupling of methods are described.

      Classification: 1b
      93 083
      Planar chromatography in veterinary toxicology
      P. BERNY*, J. SYNARDET, D. VEY, (*Toxicology Laboratory of the Ecole Nationale Veterinaire de Lyon ENVL, 1, Avenue Bourgelat, BP 83 F- 69280 Marcy L'Etoile, France)

      Analysis of choline esterase inhibitors. CBS 83, 4-5 (1999) HPTLC-AMD of choline esterase inhibitors on silica gel with a 15-step gradient from methanol via dichloromethane to hexane. Detection by spraying with butyryl choline esterase solution followed by incubation at 37 °C for 30 min, and spraying with fast blue salt mixed with alpha-naphthyl acetate followed by incubation at 37 °C for 5 min. Quantitative determination by absorbance measurement at 254 nm.

      Classification: 29, 32d
      97 128
      Analysis of ginsenosides from Panax quinquefolium L
      W. MARKOWSKI*, A. LUDWICZUK, T. WOLSKI (*Department of Physical Chemistry, Medical University, Lublin, Poland)

      by automated multiple development. J. Planar Chromatogr. 19, 115-117 (2006). HPTLC of eight ginsenosides on silica gel after cleaning with isopropanol for 1 h with methanol - chloroform. Two gradient programs and two different values of increment in the development distance were compared. Visualization by spraying with A) Godin’s reagent (5% solution of sulfuric acid in ethanol), and B) 1% solution of vanillin in ethanol, followed by heating at 105°C for 10 min. Evaluation by scanning at 540 nm.

      Classification: 32e
      103 104
      HPTLC analysis of tamoxifen citrate in drug-release media during development of an in-situ-cross-linking delivery system
      A. JAMSHIDI*, A, SHARIFI (*Iran Polymer and Petrochemical Institute, Novel Drug Delivery Systems Department, P. O. Box 14185/458 Tehran, Iran; a.jamshidi@ippi.ac.ir)

      J. Planar Chromatogr. 22, 187-189 (2009). HPTLC of tamoxifen citrate ((Z)-2-[4-(1,2-diphenylbut-1-enyl)phenoxy]ethyldimethylamine citrate) on silica gel (prewashed with methanol - chloroform 1:1) by automated multiple development (AMD 2) using single-step isocratic development with toluene - methanol - glacial acetic acid 57:38:5. Detection under UV 254 nm. Quantitative determination by absorbance measurement at 256 nm. The limit of detection and quantitation was 25 and 52 ng/band, respectively.

      Classification: 32a
      120 056
      Quantification of bitter acids in hops
      M. SCHULZ*, M. BURHOLT, J. ENGELMANN, H. GRIESINGER, M. OBERLE, V. PILAKOWSKI (*Merck KGaA, Frankfurter Str. 250, 64293 Darmstadt, Germany, michael.schulz@merckgroup.com)

      CBS 119 (2017 12-13. HPTLC of hop extracts on silica gel (MS-grade) by automated multiple development using a 9-step AMD 2 gradient based on ethyl acetate – methanol – n-heptane. Quantitative determination by fluorescence measurement at 360/>400 nm with the deuterium lamp. The hRF of α-acids was 36 and of β-acids 65 and the matrix was well separated. With this study the differences in the bitter acid content of regional and varietal hops was determined. In most cases, the bitter hops contained more bitter acids than aromatic hops.

      Classification: 11a
      69 100
      Effective systems for the separation of pharmaceutically important estrogens by thin layer chromatography
      S.K. POOLE*, M.T. BELAY, C.F. POOLE, (*Dept. of Chem., Wayne State Univ., Detroit, MI 48202, USA)

      J. Planar Chromatogr. 5, 16-27 (1992). TLC of estrogens (estrone, equilin, equilenin, 17 a & ß-dihydroequilin, 17 a & ß-dihydroequilenin, estriol) on silica, C-2, C-8, C-18, NH2- and diol-modified, with different eluents in one- and two-dimensional separations. The optimized mobile phase based on cyclohexane and ethyl acetate provided best separation of estrogens containing C-17 hydroxy group epimers, those with a C-17 keto group were only separated in mobile phases containing triethylamine (or on NH2-layers in the absence of triethylamine). 2,4-dinitrophenylhydrazones of C-17-keto group estrogens enable their selective detection at 366/>400 nm.

      Classification: 13b
      74 034
      Direct HPTLC-FTIR measurement in combination with AMD
      S.C. WOLFF, K.-A. KOVAR*, (*Pharm. Inst. der Univ. Tübingen, auf der Morgenstelle 8, D-72076 Tübingen)

      J. Planar Chromatogr. 7, 344-348 (1994), Use of AMD for the improvement of the identification and determination limit by FTIR of hexobarbital to between one half and one third of their original values; AMD can be recommended for such application. When thinner silica gel layers on a reflecting carrier are used, these values can be reduced once again (by half). In order to achieve optimum results, certain procedures must be followed: dot spotting and mobile reference measurement taken at the level of the substance to be analyzed. Detection limits for hexobarbital = 55 ng, phenobarbital = 55 ng, caffeine = 30 ng, salicylic acid = 220 ng and ascorbic acid = 240 ng. The reasons for and significance of these different limits of identification are discussed.

      Classification: 4e