Cumulative CAMAG Bibliography Service CCBS

Our CCBS database includes more than 11,000 abstracts of publications. Perform your own detailed search of TLC/HPTLC literature and find relevant information.

The Cumulative CAMAG Bibliography Service CCBS contains all abstracts of CBS issues beginning with CBS 51. The database is updated after the publication of every other CBS edition. Currently the Cumulative CAMAG Bibliography Service includes more than 11'000 abstracts of publications between 1983 and today. With the online version you can perform your own detailed TLC/HPTLC literature search:

  • Full text search: Enter a keyword, e.g. an author's name, a substance, a technique, a reagent or a term and see all related publications
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      95 090
      HPTLC method for the simultaneous estimation of valdecoxib and tizanidine hydrochloride in tablets
      A. SUGANTHI VIPIN PRAKASH*, Sapna SHRIKUMAR, K. A. Mirkasim, T. K. RAVI (*College of Pharmacy, Sri Ramakrishna Institute of Paramedical Sciences, Coimbatore 641 044, India)

      IPC 56th 2004, Abstract No. GP-3. Simultaneous HPTLC determination of valdecoxib and tizanidine in tablets on silica gel with n-butyl acetate - formic acid - chloroform 7:3:2. Quantitative determination by densitometric scanning at 283 nm. The Rf values of valdecoxib and tizanidine were 0.78 and 0.39 respectively. Linearity range was 200 - 1000 ng/spot and 60 - 300 ng/spot respectively. Mean recovery for both of the compounds was 99.57 – 101.28 %. The method was validated for accuracy, precision, linearity, LOD, and LOQ.

      Classification: 32a
      97 065
      HPTLC method for estimation of carvedilol from tablet formulation
      V.B. BADGUJAR, P.S. JAIN, G.S. TALELE, S.J. SURANA (*R.C.Patel Coll of Pharmacy, Karvand Naka, Shirpur, Dhule-425405, India)

      Indian Drugs 42 (8), 511-515 (2005). HPTLC carvedilol in tablets on silica gel with toluene - methanol - ethyl acetate - ammonia 40:10:5:1. Quantitative determination by absorbance measurement at 254 nm. The method was linear in the range of 50-250 µg/µL with recovery of 98.5-100.2 %. Stability was studied during and after development. Accuracy, precision, and specificity of the method were established.

      Classification: 32a
      98 014
      Chromatographic analysis of organic compounds on impregnated chemically bonded stationary phases
      G. GRYGIERCZYK (Inst. of Chem., Silesian Univ., 9 Szkolna Street, 40-006 Katowice, Poland)

      Part I. Acta Chrom. 17, 302-313 (2006). Non-polar (RP-2, RP-8, and RP-18) and polar (amino, cyano, and diol) chemically bonded stationary phases have been impregnated with solutions of organic substances at different concentrations and the effect of impregnation on the mechanism of retention of alcohols, higher fatty acids, amino acids, and medicines has been investigated.

      Classification: 3b
      99 054
      Alkaloid Composition of Chelidonium majus L
      Á. SÁRKOEZI*, G. JANICSÁK, L. KURSINSZKI, Á. KÉRY (*Department of Pharmacognosy, Semmelweis University, Ülloi Str. 26, 1085 Budapest, Hungary)

      Studied by Different Chromatographic Techniques. Chromatographia 63 (Supplement 13), S81 - S86 (2006). TLC of isoquinoline alkaloids (chelidonine, chelerythrine, sanguinarine, coptisine and berberine) in Chelidonium plant organs on silica gel with chloroform - methanol 2:1, and methylene chloride - methanol 97:3. Quantification by densitometry at UV 254 nm. Detection is very sensitive because of fluorescence of alkaloids without purification. Comparison with HPLC, showing that the TLC methodis the most simple, accurate, reproducible and convenient analytical technique for fast investigations and routine determination of Chelidonium alkaloids.

      Classification: 22
      100 013
      New coupling of planar chromatography with direct analysis in real time mass spectrometry
      Gertrud MORLOCK*, Y. UEDA (*Institute of Food Chemistry, University of Hohenheim, Garbenstrasse 28, D-70599 Stuttgart, Germany)

      J. Chromatogr. A 1043 (1-2), 243-251 (2007). Presentation of the coupling of planar chromatography with direct analysis in real time time-of-flight mass spectrometry (DART-TOF-MS) for the first time. By cutting the plate within a track led to substance zones positioned on the plate edge, the interested zones were directly introduced into the DART gas stream to obtain the mass signals instantaneously within seconds, giving the detectability in the very low ng/zone-range on the example of isopropylthioxanthone. The coupling was perfectly suited for identification and qualitative purposes, but for quantification of results the analytical response and the repeatability were strongly dependent from proper manual positioning of the HPTLC plate into the excited-state gas stream of the ion source. By using stable isotope-labeled standards the drawback can be overcome demonstrated with the example of caffeine, and the analytical response (r2 of 0.9892) and repeatability (RSD < ±5.4%, n = 6) were improved to a high extent. The spatial resolution by an in-house-built plate holder system was shown to be better than 3 mm; the decay of the signal was observed. Comparison of the efficacy of this new coupling to a plunger-based extraction device for HPTLC/electrospray ionization–MS. The detectability of latter showed to be down to the pg/zone-range, e.g. the limit of quantification for isopropylthioxanthone to be 100 pg/zone. The repeatability was comparable (RSD ± 6.7%), however, without the need of internal standard correction, and the analytical response slightly better (r2 of 0.9983). The spatial resolution was 2 mm or 4 mm depending on the plunger head used.

      Classification: 3f
      101 007
      Controlling best the drying step
      M. LOPPACHER (CAMAG, Sonnenmattstr. 11, CH-4132 Muttenz, Switzerland, matthias.loppacher@camag.com)

      CBS 100, 9 (2008). The drying step contributes significantly to the overall experimental variability of the TLC system. Comparison of different drying procedures demonstrated that homogenous, rapid and heatless drying by the automatic developing chamber ADC 2 reduced the overall standard deviation by up to a factor of 3 compared to manual use of a hair dryer.

      Classification: 3d
      102 042
      Total chemical analysis of the seed of Tieghemella heckelii by diverse chromatography techniques
      B.G. KIPRE, A.A. COFFI, A.A. ADIMA, T. GOKOU, Y. ITO*, B. K. GOSSE (*Center for Biochemistry and Biophysics, National Heart, Lung, and Blood Institute, National Institute of Health, Bethesda, Maryland, USA; itoy@nhlbi.nch.gov)

      J. Liq. Chromatogr. Relat. Technol. 31, 250-262 (2008). Analytical and preparative TLC of saponins (arganine A, C, D, and tieghemelin in the seed of Tieghemella heckelii) on silica gel with chloroform - methanol - 0.5 % TFA 12:8:1. Detection by spraying with a solution of 2 % cerium sulfate in 5.6 % sulfuric acid.

      Classification: 14
      104 041
      Effective and sensitive methods for quantitative analysis of alkaloids in sida species by using HPLC and HPTLC
      K. DHALWAL*, V. SHINDE, K. MAHADIK (* Dept. of Pharmacognosy and Phytochemistry, Poona College of Pharmacy, Bharathi Vidyapeeth University, Erandwane, Pune 411038, India)

      Abstract No. 9402, IHCB (2009). HPLC and HPTLC methods were developed for the simultaneous estimation of vasicine and vasicinone in Sida cordifolia and Sida acuta roots. HPTLC of vasicine and vasicinone on silica gel with ethyl acetate - methanol - ammonia 40:10:1. Quantitative determination by absorbance measurement at 300 nm. Linearity was 320-960 ng/spot (vasicine) and 80-400 ng/spot (vasicinone). Linearity by HPLC was 4-20 µg/mL. The HPTLC method was more suitable because of high throughput and low analysis time.

      Classification: 22